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(4-CHLORO-PYRIDIN-2-YL)-METHANOL

Product Name
(4-CHLORO-PYRIDIN-2-YL)-METHANOL
CAS No.
63071-10-3
Chemical Name
(4-CHLORO-PYRIDIN-2-YL)-METHANOL
Synonyms
4-Chloro-2-pyridylmethanol;CHEMPACIFIC 38138;CHEMBRDG-BB 4014670;4-CHLORO-2-PYRIDINEMETHANOL;4-Chloropyridine-2-methanol;2-Pyridinemethanol, 4-chloro-;(4-chloro-2-pyridinyl) methano;(4-chloro-2-pyridinyl)methanol;4-Chloro-2-pyridinemethanol>(4-Chloropyridine-2-yl)methanol
CBNumber
CB6153133
Molecular Formula
C6H6ClNO
Formula Weight
143.57
MOL File
63071-10-3.mol
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(4-CHLORO-PYRIDIN-2-YL)-METHANOL Property

Melting point:
0°C
Boiling point:
0°C
Density 
1.324±0.06 g/cm3(Predicted)
Flash point:
0°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
13.12±0.10(Predicted)
color 
White to Light yellow to Light orange
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Harmful/Irritant/Keep Cold
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE000344
Product name
(4-Chloro-pyridin-2-yl)-methanol
Purity
Aldrich
Packaging
1g
Price
$497
Updated
2025/07/31
TCI Chemical
Product number
C2950
Product name
4-Chloro-2-pyridinemethanol
Purity
>98.0%(GC)
Packaging
1g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
C2950
Product name
4-Chloro-2-pyridinemethanol
Purity
>98.0%(GC)
Packaging
5g
Price
$132
Updated
2025/07/31
TRC
Product number
C380635
Product name
4-Chloro-2-pyridinemethanol
Packaging
250mg
Price
$130
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
C10194
Product name
4-Chloro-2-(hydroxymethyl)pyridine
Purity
98%
Packaging
1g
Price
$5
Updated
2021/12/16
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(4-CHLORO-PYRIDIN-2-YL)-METHANOL Chemical Properties,Usage,Production

Uses

4-Chloro-2-pyridinemethanol is used in the inactivation of dimethylarginine dimethylaminohydrolase (DDAH).

Synthesis Reference(s)

Synthetic Communications, 19, p. 317, 1989 DOI: 10.1080/00397918908050984

Synthesis

24484-93-3

63071-10-3

General procedure for the synthesis of 4-chloro-2-pyridinemethanol from methyl 4-chloropyridinecarboxylate: Methyl 4-chloropyridinecarboxylate (4.0 g, 23.3 mmol) and CaCl2 (10.3 g, 93.2 mmol) were dissolved in a solvent mixture of anhydrous MeOH-THF (2:1, 30 mL) and cooled to 0 °C. NaBH4 (1.8 g, 46.6 mmol) was added in batches under stirring. The reaction mixture was kept at 0 °C for the reaction. After completion of the reaction, water was added to quench the reaction. The solvent was removed by rotary evaporator and the residue was dissolved in water and extracted with CHCl3. The organic phases were combined, dried over MgSO4, filtered and concentrated by evaporation to give 4-chloro-2-pyridine methanol (3.3 g, 98% yield) as a white solid.

References

[1] Chemical Communications, 2009, # 20, p. 2848 - 2850
[2] Bulletin of the Chemical Society of Japan, 2015, vol. 88, # 6, p. 784 - 791
[3] Synthetic Communications, 2005, vol. 35, # 24, p. 3187 - 3190
[4] Inorganic Chemistry, 2013, vol. 52, # 11, p. 6481 - 6501
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 23, p. 6483 - 6487

(4-CHLORO-PYRIDIN-2-YL)-METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-CHLORO-PYRIDIN-2-YL)-METHANOL Suppliers

Americas 1 China 146 Europe 1 Germany 3 India 3 Japan 1 United Kingdom 4 United States 22 Global 181
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from (4-CHLORO-PYRIDIN-2-YL)-METHANOL manufacturers

Dideu Industries Group Limited
Product
(4-CHLORO-PYRIDIN-2-YL)-METHANOL 63071-10-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-26
Career Henan Chemical Co
Product
(4-CHLORO-PYRIDIN-2-YL)-METHANOL 63071-10-3
Price
US $2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
customise
Release date
2018-08-09

63071-10-3, (4-CHLORO-PYRIDIN-2-YL)-METHANOLRelated Search:

4-Chloropyridine-2-carboxylic acid 3,4,5-Trichloropyridine-2-carboxylic acid (2-CHLORO-PYRIDIN-4-YL)-METHANOL Methyl 4-chloropicolinate Tetrachloropyridine-2-carboxylic acid Methyl 4-chloro-2-pyridinecarboxylate hydrochloride 4-CHLORO-PYRIDINE-2,6-DICARBOXYLIC ACID dimethyl 4-chloropyridine-2,6-dicarboxylate 4-Chloro-6-methylpyridine-2-carboxylic acid (4-Chloro-pyridin-3-yl)-methanol (2-CHLORO-PYRIDIN-3-YL)-METHANOL (5-Chloro-pyridin-3-yl)-methanol (6-CHLORO-PYRIDIN-2-YL)-METHANOL 2-(Hydroxymethyl)pyridine DIETHYL 4-CHLORO-2,6-PYRIDINEDICARBOXYLATE METHYL 3,4,5,6-TETRACHLOROPYRIDINE-2-CARBOXYLATE 3,4-DICHLOROPICOLINIC ACID ETHYL 3,4,5,6-TETRACHLOROPYRIDINE-2-CARBOXYLATE

  • 4-CHLORO-2-PYRIDINEMETHANOL
  • 4-CHLORO-2-HYDROXYMETHYLPYRIDINE
  • (4-CHLORO-PYRIDIN-2-YL)-METHANOL
  • CHEMPACIFIC 38138
  • CHEMBRDG-BB 4014670
  • 4-Chloro-2-hydroxymethylpyridine 97%
  • (4-chloro-2-pyridinyl)methanol
  • (4-chloro-2-pyridinyl) methano
  • (4-Chloropyridine-2-yl)methanol
  • 4-Chloro-2-pyridylmethanol
  • (4-chloro-2-pyridinyl)methanol (en)
  • (4-chloropyridin-2-yl)methanol(SALTDATA: 0.85HCl)
  • 4-Chloro-2-pyridinemethanol&gt
  • 2-Pyridinemethanol, 4-chloro-
  • (4-CHLORO-PYRIDIN-2-YL)-METHANOL ISO 9001：2015 REACH
  • 4-Chloropyridine-2-methanol
  • 63071-10-3
  • Building Blocks
  • Heterocycle-Pyridine series
  • API intermediates
  • Pyridine
  • Alcohols and Derivatives
  • Heterocycles
  • blocks
  • Pyridines