ChemicalBook > CAS DataBase List > (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

Product Name
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
CAS No.
23735-43-5
Chemical Name
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
Synonyms
(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate;(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE;Travoprost Impurity 51;(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE;L-α,β-Isopropylideneglycerol-γ-tosylate;(S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE;(S)-3-Toxyloxy-1,2-propanediol acetonide;2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE;(S)-1-O-tosyl-2,3-O-isopropylideneglycerol;(2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
CBNumber
CB6164890
Molecular Formula
C13H18O5S
Formula Weight
286.34
MOL File
23735-43-5.mol
More
Less

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Property

Melting point:
29-31 °C
alpha 
4.2 º (c=10, abs.alcohol)
Boiling point:
398.71°C (rough estimate)
Density 
1.208 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.506(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
form 
powder to lump to clear liquid
color 
White or Colorless to Light yellow
optical activity
[α]26/D +7.5°, c = 2% in DMF
BRN 
89799
CAS DataBase Reference
23735-43-5(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
10-21
HS Code 
29329990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
337420
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
Purity
97%
Packaging
1g
Price
$171
Updated
2023/01/07
Sigma-Aldrich
Product number
337420
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate
Purity
97%
Packaging
5g
Price
$304
Updated
2023/01/07
TCI Chemical
Product number
D2550
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Purity
>98.0%(GC)
Packaging
1g
Price
$198
Updated
2024/03/01
TCI Chemical
Product number
D2550
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Purity
>98.0%(GC)
Packaging
5g
Price
$645
Updated
2024/03/01
TRC
Product number
D469555
Product name
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate
Packaging
1g
Price
$115
Updated
2021/12/16
More
Less

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Suppliers

Discovery Fine Chemicals Ltd.
Tel
--
Fax
--
Email
info@discofinechem.com
Country
United Kingdom
ProdList
530
Advantage
58
Melrob Ltd (part of Nordmann)
Tel
--
Fax
--
Email
nquiries@melrob.com
Country
United Kingdom
ProdList
3065
Advantage
58
NiCHe Materials Ltd.
Tel
--
Fax
--
Email
Mike.Norman@NiCHeMaterials.com
Country
United Kingdom
ProdList
891
Advantage
58
Manchester Organics
Tel
--
Fax
--
Email
info@manchesterorganics.com
Country
United Kingdom
ProdList
6834
Advantage
67
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Tokyo Chemical Industry UK Ltd.
Tel
--
Fax
--
Email
sales@tci-uk.co.uk
Country
United Kingdom
ProdList
1637
Advantage
50
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82

23735-43-5, (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonateRelated Search:


  • (S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE
  • (S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE
  • (S)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE
  • (S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENSULFONATE
  • (S)-(+)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE
  • (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL-4-METHYLBENZENESULFONATE
  • (S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate
  • 2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE
  • 2,2-DIMETHYL-4(S)-4-(P-TOLYLSULFONYL)METHYL-1,3-DIOXALANE
  • 1,3-DIOXOLANE-4-METHANOL, 2,2-DIMETHYL-, 4-METHYLBENZENESULFONATE, (4S)-
  • L-α,β-Isopropylideneglycerol-γ-tosylate
  • (S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate
  • (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOLUENE-4-SULFONATE
  • (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE
  • (S)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-YLMETHYL P-TOLUENESULFONATE
  • (S)-1,2-O-ISOPROPYLIDENEGLYCEROL-3-TOLUENESULFONATE
  • (S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE
  • (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
  • (S)-3-Toxyloxy-1,2-propanediol acetonide
  • (s)-2,2-dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate
  • (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol 4-toluenesulfo
  • 2,3-Isopropylidene-sn-glycerol 1-tosylate, (S)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate, L-α,β-Isopropylideneglycerol-γ-tosylate
  • 2,3-Isopropylidene-sn-glycerol 1-tosylate, L-α,β-Isopropylideneglycerol-γ-tosylate
  • (2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
  • 4-Methylbenzenesulfonic acid (S)-2,2-dimethyl-1,3-dioxolane-4α-ylmethyl ester
  • p-Toluenesulfonic acid [(S)-2,2-dimethyl-1,3-dioxolane-4α-yl]methyl ester
  • p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolan-4-ylmethyl ester
  • p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolane-4-ylmethyl ester
  • (S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate,97%
  • L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL-GAMMA-TOSYLATE
  • L-(+)-1,2-ISOPROPYLIDENEGLYCEROL 3-(P-TOLUENESULFONATE)
  • (4S)-2,2-dimethyl-4-(4-toluenesulphonyloxymethyl)-1,3-dioxolane
  • (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethylp-Toluenesulfonate&gt
  • 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-(4-methylbenzenesulfonate), (4S)-
  • Travoprost Impurity 51
  • (S)-(2,2-dimethyl-1,3-dioxalan-4-yl)methyl-4-methylbenzenesulfonate
  • (S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-tolue...
  • (S)-1-O-tosyl-2,3-O-isopropylideneglycerol
  • 23735-43-5
  • Asymmetric Synthesis
  • Organic Building Blocks
  • Protected Alcohols
  • Dioxolanes
  • Chiral Building Blocks
  • Dioxanes & Dioxolanes
  • Glycidyl Compounds, etc. (Chiral)
  • chiral
  • Chiral Building Blocks
  • Dioxanes & Dioxolanes
  • Dioxolanes
  • Glycidyl Compounds, etc. (Chiral)
  • Synthetic Organic Chemistry
  • ADVANCED INT.