Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Property

Boiling point:

100.1℃ at 101.325kPa

Density 

d20 1.19

vapor pressure 

0.003-17Pa at 20-45℃

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Soluble), DMSO (Slightly), Methanol (Slightly), Water

form 

Liquid

PH

3.43 at 20℃ and 10g/L

LogP

-0.34-0.81 at 10-30℃ and pH5-9

Surface tension

72.6-73mN/m at 1-1.106g/L and 19.5-20℃

Dissociation constant

2.81-4.2 at 20-25℃

EPA Substance Registry System

5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone (55965-84-9)

Safety

Toxicity

LD50 (mg/kg) orally in rabbits: 30; i.p. in male, female rats: 4.6, 4.3; LC50 (6 day) in trout, sunfish (mg/l): 0.14, 0.54; LC50 (8 day dietary) in Bobwhite quail, Peking duck (mg/kg/day): >60, >100 (J. Am. Coll. Toxicol.)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H310Fatal in contact with skin

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H330Fatal if inhaled

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Chemical Properties,Usage,Production

Description

Kathon 886 metalwork fluid is a mixture of the two isothiazoliones contained in Kathon CG, at a 13.9% concentration. It is mainly contained in metalwork fluids. As an active component of Aigezid Ⅱ and contained in a water bath used for phtotographic development, it caused contact dermatitis in a photograph developer.

Description

Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides. It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively. MCIT/MIT can elicit contact sensitization. Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products.

Uses

Antimicrobial preservative in cosmetics, hygeine products, paints, emulsions, cutting oils, paper coatings, and water storage and cooling units.

Hazard

A poison by ingestion.

Contact allergens

Kathon? CG (CG = cosmetic grade) is a 3:1 mixture of CMI and MI, at a 1.5% concentration. It is used for cosmetics and toiletries, metalworking fluids or paints, in which it can be added only periodically or in color film developers. Kathon? 886 MW (MW = metalworking fluids) is a mixture CMI/MI mixture at a 13.9% concentration, mainly contained in metalworking fluids. Kathon? FP 1.5 contains MCI/MI at 1.5% concentration in propylene glycol. Kathon? LX (LX = LateX) contains MCI/MI at a tenfold concentration of Kathon? CG. Kathon? WT (WT = water treatment) is a MCI/MI mixture used in the paper industry. Parmetol? K40, Parmethol? DF 12 and Parmetol? DF 35, Parmetol? A 23, Parmetol? K50, and Parmetol? DF 18 are other brand names of MCI/MI.