Phenanthridine

Product Name: Phenanthridine
CAS No.: 229-87-8
Chemical Name: Phenanthridine
Synonyms: PHENANTHRIDIN;9-Azaphenanthrene;5-azaphenanthrene;BENZO[C]QUINOLINE;3,4-BENZOQUINOLINE;3,4-Benzoisoquinoline;Phenathridine;PHENANTHRIDINE;6-Phenanthridine;Phenanthridine>
CBNumber: CB6239037
Molecular Formula: C13H9N
Formula Weight: 179.22
MOL File: 229-87-8.mol

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Phenanthridine Property

Melting point:: 104-107 °C (lit.)
Boiling point:: 349 °C/769 mmHg (lit.)
Density: 1.1255 (rough estimate)
refractive index: 1.7270 (estimate)
Flash point:: 100 °C
solubility: phosphate buffer: soluble
pka: 5.58(at 20℃)
form: Powder
color: White to beige
Water Solubility: 0.3g/L(20 ºC)
BRN: 120204
CAS DataBase Reference: 229-87-8(CAS DataBase Reference)
EPA Substance Registry System: Phenanthridine (229-87-8)

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: SF7928000
HS Code: 29333990
Toxicity: mic-bac-sat 50 mg/plate 50NNAZ7,73,83

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 157384
Product name: Phenanthridine
Purity: 98%
Packaging: 5g
Price: $170
Updated: 2024/03/01

Sigma-Aldrich

Product number: 262692
Product name: Phenanthridine
Purity: ≥99%, purified by sublimation
Packaging: 1g
Price: $105
Updated: 2023/01/07

TCI Chemical

Product number: P1047
Product name: Phenanthridine
Purity: >98.0%(GC)
Packaging: 10g
Price: $194
Updated: 2024/03/01

Sigma-Aldrich

Product number: 77490
Product name: Phenanthridine
Purity: BioReagent, suitable for fluorescence, ≥98.0% (GC)
Packaging: 1g
Price: $85.9
Updated: 2021/12/16

TRC

Product number: P312653
Product name: Phenanthridine
Packaging: 1g
Price: $110
Updated: 2021/12/16

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Phenanthridine Chemical Properties,Usage,Production

Chemical Properties

white to beige powder

History

Phenanthridine was first discovered by Ame Pictet and H. J. Ankersmit in 1891 by pyrolysis of the condensed product of benzaldehyde and aniline. Earlier, phenanathridine and related compounds were prepared using mainly Pictect-Hurbert and modified Morgan-Walls type of condensation reactions.

Uses

Phenanthridine is an isomeric compound of acridine. It is a nitrogen heterocycle that is the basis of DNA-binding fluorescent dyes through intercalation. Ethidium bromide and propidium iodide are the examples of such intercalating dyes. It is used as a dye in biological and chemical sensors. It is also used in the study of ecotoxicity and rotational spectroscopic investigations and radio astronomical searches.

Definition

ChEBI: Phenanthridine is an azaarene that is the 9-aza derivative of phenanthrene. The parent of the class of phenanthridines. It is a mancude organic heterotricyclic parent, a polycyclic heteroarene, a member of phenanthridines and an azaarene.

Preparation

Palladium catalyzed synthesis of phenanthridine has been accomplished by Pritchard and coworkers from imidoyl selenides. This was the first report of palladium insertion into the C-Se bond. The palladium insertion into the imidoyl selenides 3.20 followed by intramolecular cyclization and subsequent aromatization via the elimination of HSePh lead to the formation of substituted phenanthridines 3.21.

Pd-catalysed synthesis of phenanathridine

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 6295, 1952 DOI: 10.1021/ja01144a521
Journal of Heterocyclic Chemistry, 26, p. 865, 1989 DOI: 10.1002/jhet.5570260366
Tetrahedron Letters, 29, p. 5463, 1988 DOI: 10.1016/S0040-4039(00)80787-X

General Description

Phenanthridine appears as crystalline needles. Mutagenic.

Air & Water Reactions

Sparingly soluble in water.

Reactivity Profile

PHENANTHRIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

Flash point data are not available for PHENANTHRIDINE, but is probably combustible.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

Phenanthridine Preparation Products And Raw materials

Raw materials

Preparation Products

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Phenanthridine Suppliers

Americas 1 Belgium 1 Canada 1 China 51 Europe 1 Germany 5 India 3 Japan 2 Norway 1 South Korea 1 Switzerland 3 The Netherlands 1 United Kingdom 9 United States 14 Global 94

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
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Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

Syntechem Co.,Ltd

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Country: China
ProdList: 12984
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Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
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Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
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Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
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View Lastest Price from Phenanthridine manufacturers

R&D Scientific Inc.

Product: Phenanthridine 229-87-8
Price: US $2400.00/g
Min. Order: 1g
Purity: 97
Supply Ability: 500 Kg
Release date: 2024-03-19

Career Henan Chemical Co

Product: PHENANTHRIDINE 229-87-8
Price: US $1.80/KG
Min. Order: 1g
Purity: 90.0%-99.9%
Supply Ability: 800kg
Release date: 2020-03-20

229-87-8, PhenanthridineRelated Search:

FLAVANTHRONE Dimidium bromide Nitidine chloride 3,8-DIAMINO-6-PHENYLPHENANTHRIDINE Macleaya cordata extract SANGUINARINE NITRATE Phenanthridine SANGUINARINE CHLORIDE pyritidium bromide Propidium iodide CHELERYTHRINE CHLORIDE DIMIDIUM BROMIDE MONOHYDRATE Ethidium bromide 6(5H)-Phenanthridone Isometamidium chloride 12,13-Dihydro-1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridine,12,13-Dihydro-1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridine Chelerythrine 3,8-DINITRO-6-PHENYLPHENANTHRIDINE

3,4-Benzoisoquinoline

5-azaphenanthrene

6-Phenanthridine

9-Azaphenanthrene

PHENANTHRIDIN

PHENANTHRIDINE

3,4-BENZOQUINOLINE

BENZO[C]QUINOLINE

Phenanthridine, 98% 1GR

3,4-Benzoquinoline Benzo[c]quinoline

Phenathridine

PHENANTHRIDINE, SUBLIMED, 99+%

PHENANTHRIDINE, FOR FLUORESCENCE

Phenanthridine, 98+%

Phenanthridine&gt

Benzo[c]quinoline in toluene

229-87-8

Fluorescent Probes, Labels, Particles and Stains

Detection

Biochemicals and Reagents

BioChemical