ChemicalBook > CAS DataBase List > HO-PEG10-tBu

HO-PEG10-tBu

Product Name: HO-PEG10-tBu
CAS No.: 778596-26-2
Chemical Name: HO-PEG10-tBu
Synonyms: PEG11-t-butly ester;HO-PEG10-CH2CH2COOtBu;HO-PEG10-tBu;OH-PEG10-TBA;HO-PEG-PA-OtBu;HO-PEG10-COOtBu;Hydroxy-PEG10-Boc;OH-PEG10-CH2CH2COOtBu;Hydroxy-PEG10-t-butyl ester;Hydroxy-PEG10-t-butly ester
CBNumber: CB62546894
Molecular Formula: C27H54O13
Formula Weight: 586.71
MOL File: 778596-26-2.mol

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HO-PEG10-tBu Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DMF, DCM
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C27H54O13/c1-27(2,3)40-26(29)4-6-30-8-10-32-12-14-34-16-18-36-20-22-38-24-25-39-23-21-37-19-17-35-15-13-33-11-9-31-7-5-28/h28H,4-25H2,1-3H3
InChIKey: AEEGJXDZOJNBIY-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific

Product number: BIPG1455
Product name: Hydroxy-PEG10-t-butylester
Packaging: 100mg
Price: $138
Updated: 2021/12/16

BroadPharm

Product number: BP-22607
Product name: Hydroxy-PEG10-t-butylester
Purity: 98%
Packaging: 500mg
Price: $200
Updated: 2021/12/16

chempep

Product number: 280504
Product name: HO-PEG10-tBu
Purity: >=95%
Packaging: 1g
Price: $305
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1455
Product name: Hydroxy-PEG10-t-butylester
Packaging: 500mg
Price: $435
Updated: 2021/12/16

BroadPharm

Product number: BP-22607
Product name: Hydroxy-PEG10-t-butylester
Purity: 98%
Packaging: 2g
Price: $450
Updated: 2021/12/16

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HO-PEG10-tBu Chemical Properties,Usage,Production

Description

Hydroxy-PEG10-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)[2].

References

[1] Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent CN108707228A.
[2] Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5. DOI:10.1021/jm049705s

HO-PEG10-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from HO-PEG10-tBu manufacturers

LAURENT

Product: HO-PEG10-CH2CH2COOtBu 778596-26-2
Price: US $180.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 200kg
Release date: 2025-11-17

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: tert-butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate 778596-26-2
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: Hydroxy-PEG10-t-butyl ester 778596-26-2
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

778596-26-2, HO-PEG10-tBuRelated Search:

Hydroxy-PEG3-ethyl ester FMOC-GAMMA-ABU-OH HO-PEG8-CH2CH2COOH Fmoc-9-Amino-4,7-Dioxanonanoic acid TETRAETHYLENEGLYCOL MONOMETHYL ETHER 2,5,8,11,14,17-Hexaoxanonadecan-19-amine OCTAETHYLENE GLYCOL Z-8-aMino-3,6-dioxaoctanoic acid O-METHYL-UNDECAETHYLENE GLYCOL Boc-1-amino-3,6-dioxa-8-octanediamine alpha-aMine-oMega-propionic acid hexaethylene glycol alpha-aMine-oMega-propionic acid octaethylene glycol 1-Azidohexaethylene Glycol HS-PEG4-CH2CH2COOH alpha-MaleiMidopropionyl-oMega-succiniMidyl-10(ethylene glycol) H2N-PEG8-tBu H2N-PEG24-tBu PENTAETHYLENE GLYCOL MONOMETHYL ETHER

HO-PEG10-CH2CH2COOtBu

PEG11-t-butly ester

HO-PEG10-tBu

33-Hydroxy-4,7,10,13,16,19,22,25,28,31-decaoxatritriacontanoic acid 1,1-dimethylethyl ester

HO-PEG10-CH2CH2COOtBu

Hydroxy-PEG10-t-butly ester

Hydroxy-PEG10-t-butyl ester

OH-PEG10-CH2CH2COOtBu

OH-PEG10-TBA

tert-Butyl 1-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate

HO-PEG10-COOtBu

Hydroxy-PEG10-Boc

Hydroxy-PEG10-t-butyl ester,HO-PEG10-tBu

4,7,10,13,16,19,22,25,28,31-Decaoxatritriacontanoic acid, 33-hydroxy-, 1,1-dimethylethyl ester

[HO-PEG-PA-OtBu] α-Hydroxyl-ω-tert butyl propionate poly(ethylene glycol)

HO-PEG10-CH2CH2COOtBu/4,7,10,13,16,19,22,25,28,31-Decaoxatritriacontanoic acid, 33-hydroxy-, 1,1-dimethylethyl ester

tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

HO-PEG-PA-OtBu

778596-26-2

C27H54O13

peg