HO-PEG10-tBu

Product Name: HO-PEG10-tBu
CAS No.: 778596-26-2
Chemical Name: HO-PEG10-tBu
Synonyms: PEG11-t-butly ester;HO-PEG10-CH2CH2COOtBu;HO-PEG10-tBu;OH-PEG10-TBA;HO-PEG-PA-OtBu;HO-PEG10-COOtBu;Hydroxy-PEG10-Boc;OH-PEG10-CH2CH2COOtBu;Hydroxy-PEG10-t-butyl ester;Hydroxy-PEG10-t-butly ester
CBNumber: CB62546894
Molecular Formula: C27H54O13
Formula Weight: 586.71
MOL File: 778596-26-2.mol

More

Less

HO-PEG10-tBu Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DMF, DCM
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C27H54O13/c1-27(2,3)40-26(29)4-6-30-8-10-32-12-14-34-16-18-36-20-22-38-24-25-39-23-21-37-19-17-35-15-13-33-11-9-31-7-5-28/h28H,4-25H2,1-3H3
InChIKey: AEEGJXDZOJNBIY-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Apolloscientific

Product number: BIPG1455
Product name: Hydroxy-PEG10-t-butylester
Packaging: 100mg
Price: $138
Updated: 2021/12/16

BroadPharm

Product number: BP-22607
Product name: Hydroxy-PEG10-t-butylester
Purity: 98%
Packaging: 500mg
Price: $200
Updated: 2021/12/16

chempep

Product number: 280504
Product name: HO-PEG10-tBu
Purity: >=95%
Packaging: 1g
Price: $305
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1455
Product name: Hydroxy-PEG10-t-butylester
Packaging: 500mg
Price: $435
Updated: 2021/12/16

BroadPharm

Product number: BP-22607
Product name: Hydroxy-PEG10-t-butylester
Purity: 98%
Packaging: 2g
Price: $450
Updated: 2021/12/16

More

Less

HO-PEG10-tBu Chemical Properties,Usage,Production

Description

Hydroxy-PEG10-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Hydroxy-PEG10-Boc is extacted from patent CN108707228 (example 0024)[1]. Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel (HY-B0015) or docetaxel (HY-B0011)[2].

References

[1] Huli, et al. A kind of preparation method of hydroxyl polyethylene glycol propionic ester. Patent CN108707228A.
[2] Miller ML, et al. Synthesis of taxoids with improved cytotoxicity and solubility for use in tumor-specific delivery.J Med Chem. 2004 Sep 23;47(20):4802-5. DOI:10.1021/jm049705s

HO-PEG10-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

HO-PEG10-tBu Suppliers

China 73 India 1 United Kingdom 1 United States 8 Global 83

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

More

Less

View Lastest Price from HO-PEG10-tBu manufacturers

LAURENT

Product: HO-PEG10-CH2CH2COOtBu 778596-26-2
Price: US $180.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 200kg
Release date: 2025-11-17

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: tert-butyl 1-hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate 778596-26-2
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: Hydroxy-PEG10-t-butyl ester 778596-26-2
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

778596-26-2, HO-PEG10-tBuRelated Search:

Hydroxy-PEG3-ethyl ester FMOC-GAMMA-ABU-OH HO-PEG8-CH2CH2COOH Fmoc-9-Amino-4,7-Dioxanonanoic acid TETRAETHYLENEGLYCOL MONOMETHYL ETHER 2,5,8,11,14,17-Hexaoxanonadecan-19-amine OCTAETHYLENE GLYCOL Z-8-aMino-3,6-dioxaoctanoic acid O-METHYL-UNDECAETHYLENE GLYCOL Boc-1-amino-3,6-dioxa-8-octanediamine alpha-aMine-oMega-propionic acid hexaethylene glycol alpha-aMine-oMega-propionic acid octaethylene glycol 1-Azidohexaethylene Glycol HS-PEG4-CH2CH2COOH alpha-MaleiMidopropionyl-oMega-succiniMidyl-10(ethylene glycol) H2N-PEG8-tBu H2N-PEG24-tBu PENTAETHYLENE GLYCOL MONOMETHYL ETHER

HO-PEG10-CH2CH2COOtBu

PEG11-t-butly ester

HO-PEG10-tBu

33-Hydroxy-4,7,10,13,16,19,22,25,28,31-decaoxatritriacontanoic acid 1,1-dimethylethyl ester

HO-PEG10-CH2CH2COOtBu

Hydroxy-PEG10-t-butly ester

Hydroxy-PEG10-t-butyl ester

OH-PEG10-CH2CH2COOtBu

OH-PEG10-TBA

tert-Butyl 1-Hydroxy-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oate

HO-PEG10-COOtBu

Hydroxy-PEG10-Boc

Hydroxy-PEG10-t-butyl ester,HO-PEG10-tBu

4,7,10,13,16,19,22,25,28,31-Decaoxatritriacontanoic acid, 33-hydroxy-, 1,1-dimethylethyl ester

[HO-PEG-PA-OtBu] α-Hydroxyl-ω-tert butyl propionate poly(ethylene glycol)

HO-PEG10-CH2CH2COOtBu/4,7,10,13,16,19,22,25,28,31-Decaoxatritriacontanoic acid, 33-hydroxy-, 1,1-dimethylethyl ester

tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

HO-PEG-PA-OtBu

778596-26-2

C27H54O13

peg