Description References
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Urease

Description References
Product Name
Urease
CAS No.
9002-13-5
Chemical Name
Urease
Synonyms
URH;UREASE;3.5.1.5;EC 3.5.1.5;EC 6.3.4.6;ensiformis;Urease,jack;Urease Bean;Urease(URH);IUB: 3.5.1.5
CBNumber
CB6263726
Molecular Formula
N/A
Formula Weight
0
MOL File
Mol file
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Urease Property

storage temp. 
2-8°C
form 
powder
color 
yellow
Water Solubility 
It is slightly soluble in water.
Merck 
14,9870
EPA Substance Registry System
Urease (9002-13-5)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-42
Safety Statements 
22-24-26-36/37-45-36-23
WGK Germany 
1
RTECS 
YU1700000
10-21
TSCA 
Yes
HS Code 
35079090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U4002
Product name
Urease from Canavalia ensiformis (Jack bean)
Purity
Type IX, powder, 50,000-100,000?units/g solid
Packaging
20000units
Price
$92.4
Updated
2024/03/01
Sigma-Aldrich
Product number
U4002
Product name
Urease from Canavalia ensiformis (Jack bean)
Purity
Type IX, powder, 50,000-100,000?units/g solid
Packaging
100000units
Price
$280
Updated
2024/03/01
Sigma-Aldrich
Product number
U7752
Product name
Urease from Canavalia ensiformis (Jack bean)
Packaging
1vial
Price
$105
Updated
2024/03/01
Sigma-Aldrich
Product number
U4002
Product name
Urease from Canavalia ensiformis (Jack bean)
Purity
Type IX, powder, 50,000-100,000?units/g solid
Packaging
500000units
Price
$1010
Updated
2024/03/01
Sigma-Aldrich
Product number
U4002
Product name
Urease from Canavalia ensiformis (Jack bean)
Purity
Type IX, powder, 50,000-100,000?units/g solid
Packaging
1000000units
Price
$1750
Updated
2024/03/01
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Urease Chemical Properties,Usage,Production

Description

Urease is found in the natural environment (water and soil) and in human body, where its occurrence is connected with protein degradation. It is an enzyme and is capable of urea hydrolysis: one molecule of ammonia and one molecule of carbamate appear in the first step, carbamate spontaneously converts into the second ammonia molecule and carbonic acid in a water solution, and ammonia is protonated. This urea hydrolysis results in pH increase. Urease and ammonia, generated during urea hydrolysis, may be toxic for human tissue and probably have role in long-lasting diseases, like atherosclerosis, urinary tract infections, or rheumatoid arthritis.
Urease can be used to analyze urea concentration in blood, urine, alcoholic beverages, natural water and environmental wastewaters; to analyze heavy metal content in natural waters, wastewaters and soil; to determine creatinine, arginine and IgG;  to remove urea from artificial kidney dialyzates, alcohol beverages and fertilizer wastewaters; to control or shift pH for multi-enzyme reaction system; to hydrolyze urea as sources of ammonia or carbon dioxide in special cases, and for the wastewater reclamation for life support systems in space.

References

[1] Iwona Konieczna, Paulina ?arnowiec, Marek Kwinkowski, Beata Kolesińska, Justyna Fr?czyk, Zbigniew Kamiński, Wies?aw Kaca (2012) Bacterial Urease and its Role in Long-Lasting Human Diseases, Curr Protein Petp Sci., 13, 789-806
[2] Yingjie Qin, Joaquim M. S. Cabral (2002) Review: Properties and Applications of Urease, Biocatalysis and Biotransformation, 20, 1-14

Chemical Properties

powder

Uses

Urease from Canavalia ensiformis may be used for urea determination of various samples, such as legumes. It may be useful for the detection of pathogens as well as heavy-metal ions.

Uses

Urease from Canavalia ensiformis may be used for urea determination of various samples, such as legumes . It may be useful for the detection of pathogens as well as heavy-metal ions.

Uses

Clinical reagent in determination of urea in body fluid.

General Description

Subunit molecular weight: ~90,770
Composed of six subunits with total molecular weight: ~544,620

Agricultural Uses

Urease, an enzyme, converts urea into ammonium carbonate [(NH4)2CO3] that releases ammonia. Thus, the enzyme activates the hydrolysis of urea. When the release occurs on or near the soil surface, ammonia is lost to the air; if it occurs near the seeds, they fail to germinate, or it proves to be toxic to the roots of young saplings. Crops can get affected by a high concentration of ammonia. Soybean, jack beans and a number of fungi are sources of urease. Its isoelectric point is pH 5.5.
Urease enzyme catalyzes the hydrolysis of urea which occurs readily in the soils. Large numbers of bacteria, fungi and actinomycetes in soils possess urease. A small group of bacteria, known as urea bacteria, have an exceptional ability to decompose urea. Activity increases in proportion with the size of the soil microbial population and the organic matter content. The presence of relatively fresh plant residues often results in abundant supplies of urease. The greatest activity of urease is reported to occur in the rhizosphere, where microbial activity is high and where it can be excreted from the plant roots.
Although warm temperature (up to 37°C) favors urease activity, the hydrolysis of urea occurs at significant rates at temperatures down to 2°C. The effects of soil moisture levels on urease activity are generally small in comparison to the influence of the pH and temperature. Free ammonia inhibits the enzymatic action of urease.

Biochem/physiol Actions

Urease catalyzes the hydrolysis of urea into carbon dioxide and ammonia. Urease is involved in nitrogen metabolism and urea degradation. Urease from Canavalia ensiformis binds 2 nickel ions per subunit .

Urease Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Urease manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Urease 9002-13-5
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-08-27
Shaanxi Dideu Medichem Co. Ltd
Product
Urease 9002-13-5
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000Tons
Release date
2024-08-21
Henan Fengda Chemical Co., Ltd
Product
Urease 9002-13-5
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09

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