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Carboxyatractyloside

Product Name
Carboxyatractyloside
CAS No.
77228-71-8
Chemical Name
Carboxyatractyloside
Synonyms
Carboxyatractyloside, 10 mM in DMSO;Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Carboxyatractyloside potassium salt - Bio-X ?;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
CBNumber
CB62677293
Molecular Formula
C31H46O18S2
Formula Weight
770.81
MOL File
77228-71-8.mol
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Carboxyatractyloside Property

Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: ≥10mg/mL
pka
-3?+-.0.18(Predicted)
form 
solid
color 
white
biological source
Xanthium sibiricum
optical activity
[α]/D -34 to -48°, c =0.5 in water
Water Solubility 
H2O: ≥10mg/mL
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
36/37-45
RIDADR 
UN 2811 6.1 / PGI
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C4992
Product name
Carboxyatractyloside potassium salt
Purity
≥98% (HPLC), from
Packaging
2mg
Price
$199
Updated
2023/01/07
ChemScene
Product number
CS-0017047
Product name
Carboxyatractyloside
Packaging
5mg
Price
$250
Updated
2021/12/16
AvaChem
Product number
3202A
Product name
Carboxyatractyloside
Packaging
10mg
Price
$290
Updated
2021/12/16
Arctom
Product number
AS713545
Product name
Carboxyatractyloside
Purity
≥98%
Packaging
100mg
Price
$342
Updated
2021/12/16
Crysdot
Product number
CD11059260
Product name
Carboxyatractylosidetripotassiumsalt
Purity
97%
Packaging
10mg
Price
$380
Updated
2021/12/16
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Carboxyatractyloside Chemical Properties,Usage,Production

Chemical Properties

White powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Atractylodes lancea.

Uses

Carboxyatractyloside potassium salt has been used as an activator of Ca2+-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.

Biochem/physiol Actions

Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.

target

Calcium Channel | P450 (e.g. CYP17)

Carboxyatractyloside Preparation Products And Raw materials

Raw materials

Preparation Products

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Carboxyatractyloside Suppliers

China 143 India 1 United Kingdom 1 United States 10 Global 155
ALB Technology Limited
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702-983-3769
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702-983-3769
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sales@albtechnology.com
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United States
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EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
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info@emmx.com
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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BOC Sciences
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+1-631-485-4226
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1-631-614-7828
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inquiry@bocsci.com
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United States
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
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support@targetmol.com
Country
United States
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Riedel-de Haen AG
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Quality Phytochemicals LLC
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MedChemExpress
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INDOFINE Chemical Company, Inc.
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FortopChem Technology Limited
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sales@fortopchem.com
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View Lastest Price from Carboxyatractyloside manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Carboxyatractyloside Potassium Salt 77228-71-8
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-03
Career Henan Chemical Co
Product
Carboxyatractyloside tripotassium salt 77228-71-8
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

77228-71-8, CarboxyatractylosideRelated Search:

3-Dimethylamino-1-propanol Acetoin Cupric acetate monohydrate Madecassoside ATRACTYLOSIDE POTASSIUM SALT ALLEOSIDE A Terrestrosin D xanthatin Xanthiside roburic acid Poricoic acid A(F) Pachymic acid 1,3,5-Tricaffeoylquinic acid Terrestrosin K Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate

  • (2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
  • Carboxyatractyloside tripotassium salt
  • Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-
  • Carboxyatractylosidetripotassiumsal
  • Carboxyatractyloside, 10 mM in DMSO
  • Carboxyatractyloside potassium salt - Bio-X ?
  • 77228-71-8
  • C31H46O18S2
  • C31H43O18S2K3
  • C31H43K3O18S2
  • reagent
  • standard substance
  • chemical reagent
  • herbal extract
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).