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Carboxyatractyloside

Product Name
Carboxyatractyloside
CAS No.
77228-71-8
Chemical Name
Carboxyatractyloside
Synonyms
Carboxyatractyloside, 10 mM in DMSO;Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
CBNumber
CB62677293
Molecular Formula
C31H46O18S2
Formula Weight
770.81
MOL File
77228-71-8.mol
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Carboxyatractyloside Property

Density 
1.58±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: ≥10mg/mL
pka
-3?+-.0.18(Predicted)
form 
solid
color 
white
optical activity
[α]/D -34 to -48°, c =0.5 in water
biological source
Xanthium sibiricum
Water Solubility 
H2O: ≥10mg/mL
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
36/37-45
RIDADR 
UN 2811 6.1 / PGI
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C4992
Product name
Carboxyatractyloside potassium salt
Purity
≥98% (HPLC), from
Packaging
2mg
Price
$199
Updated
2023/01/07
ChemScene
Product number
CS-0017047
Product name
Carboxyatractyloside
Packaging
5mg
Price
$250
Updated
2021/12/16
AvaChem
Product number
3202A
Product name
Carboxyatractyloside
Packaging
10mg
Price
$290
Updated
2021/12/16
Arctom
Product number
AS713545
Product name
Carboxyatractyloside
Purity
≥98%
Packaging
100mg
Price
$342
Updated
2021/12/16
Crysdot
Product number
CD11059260
Product name
Carboxyatractylosidetripotassiumsalt
Purity
97%
Packaging
10mg
Price
$380
Updated
2021/12/16
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Carboxyatractyloside Chemical Properties,Usage,Production

Uses

Carboxyatractyloside potassium salt has been used as an activator of Ca2+-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.

Biochem/physiol Actions

Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.

target

Calcium Channel | P450 (e.g. CYP17)

Carboxyatractyloside Preparation Products And Raw materials

Raw materials

Preparation Products

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Carboxyatractyloside Suppliers

China 117 India 1 United Kingdom 1 United States 10 Global 129
ALB Technology Limited
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702-983-3769
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702-983-3769
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sales@albtechnology.com
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United States
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EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
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info@emmx.com
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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United States
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BOC Sciences
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+1-631-485-4226
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1-631-614-7828
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inquiry@bocsci.com
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United States
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TargetMol Chemicals Inc.
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support@targetmol.com
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United States
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Riedel-de Haen AG
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Quality Phytochemicals LLC
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MedChemExpress
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INDOFINE Chemical Company, Inc.
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FortopChem Technology Limited
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View Lastest Price from Carboxyatractyloside manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Carboxyatractyloside Potassium Salt 77228-71-8
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-04-03
Career Henan Chemical Co
Product
Carboxyatractyloside tripotassium salt 77228-71-8
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

77228-71-8, CarboxyatractylosideRelated Search:

3-Dimethylamino-1-propanol Acetoin Cupric acetate monohydrate Madecassoside ATRACTYLOSIDE POTASSIUM SALT ALLEOSIDE A Terrestrosin D xanthatin Xanthiside roburic acid Poricoic acid A(F) Pachymic acid 1,3,5-Tricaffeoylquinic acid Terrestrosin K Madecassic acid dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate

  • (2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
  • Carboxyatractyloside tripotassium salt
  • Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-
  • Carboxyatractylosidetripotassiumsal
  • Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-
  • Carboxyatractyloside, 10 mM in DMSO
  • 77228-71-8
  • C31H46O18S2
  • reagent
  • standard substance
  • chemical reagent
  • herbal extract
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).