ChemicalBook > CAS DataBase List > ML355

ML355

Product Name: ML355
CAS No.: 1532593-30-8
Chemical Name: ML355
Synonyms: ML355;VLX1005;VLX-1005;VLX 1005;ML355 (ML 355;ML 355;ML-355;ML355;ML355, 10 mM in DMSO;12-LOX enzyme inhibitor;ML355,LOX,ML-355,Lipoxygenase,Inhibitor,inhibit,ML 355;N-(benzo[d]thiazol-2-yl)-4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide
CBNumber: CB62715654
Molecular Formula: C21H19N3O4S2
Formula Weight: 441.52
MOL File: 1532593-30-8.mol

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ML355 Property

Melting point:: >182°C (dec.)
Boiling point:: 654.5±65.0 °C(Predicted)
Density: 1.481±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Pyridine (Very Slightly)
form: Solid
pka: 7.58±0.30(Predicted)
color: Pale Beige to Beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18537
Product name: ML355
Purity: ≥95%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 18537
Product name: ML355
Purity: ≥95%
Packaging: 5mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 18537
Product name: ML355
Purity: ≥95%
Packaging: 10mg
Price: $333
Updated: 2024/03/01

Cayman Chemical

Product number: 18537
Product name: ML355
Purity: ≥95%
Packaging: 25mg
Price: $711
Updated: 2024/03/01

Usbiological

Product number: 456381
Product name: ML355
Packaging: 1mg
Price: $312
Updated: 2021/12/16

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ML355 Chemical Properties,Usage,Production

Uses

ML355 is used in the synthesis, structural activity relationship of benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase.

in vivo

ML355 (1.88-30 mg/kg; i.g.; 2 times per day for two days) strongly inhibits the thrombus formation in mice at higher dose compared to WT controls^[3].

Animal Model:	C57BL/6 mice^[3]
Dosage:	1.88, 3.75, 7.5, 15, 30 mg/kg
Administration:	Oral gavage; 2 times per day for two days
Result:	The thrombus formation in mice was strongly inhibited by higher doses of ML355.

IC 50

12-LOX: 0.34 μM (IC₅₀)

ML355 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML355 Suppliers

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1532593-30-8, ML355Related Search:

ML188 ML418 [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone ML213 N-(3,4-difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine PTP1B-IN-2 ML264 ML216 ML385 ML365 ML 141 M348 ml390 (2,4,6-Trichloro-phenoxy)-acetic acid (1H-pyrrol-2-ylmethylene)-hydrazide 5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one ML277 ML364 VU0456810

N-2-Benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]benzenesulfonamide

ML 355;ML-355;ML355

N-(benzo[d]thiazol-2-yl)-4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide

ML355

Benzenesulfonamide, N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-

ML355,LOX,ML-355,Lipoxygenase,Inhibitor,inhibit,ML 355

12-LOX enzyme inhibitor

VLX 1005

VLX1005

VLX-1005

ML355, 10 mM in DMSO

ML355 (ML 355

1532593-30-8

API