ChemicalBook > CAS DataBase List > H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2

H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2

Product Name
H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
CAS No.
202801-92-1
Chemical Name
H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
Synonyms
Rat orexin B;OREXIN B (MOUSE);HYPOCRETIN-B, MOUSE;OREXIN B (RAT, MOUSE);OREXIN B (MOUSE, RAT);OREXIN-B (RAT, HUMAN);Hypocretin-2 (Mouse, rat);Orexin B, mouse/rat - 1 mg;OREXINS OREXIN B RAT, MOUSE;RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2
CBNumber
CB6303550
Molecular Formula
C126H215N45O34S
Formula Weight
2936.4
MOL File
202801-92-1.mol
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H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2 Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in 1% acetic acid at 1mg/ml
form 
Solid
color 
White to off-white
Water Solubility 
Soluble in water (1 mg/ml)
Sequence
Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1457
Product name
OrexinB(mouse)
Packaging
500U
Price
$314
Updated
2021/12/16
Usbiological
Product number
O7501-02A
Product name
Orexin B, Mouse
Packaging
1mg
Price
$531
Updated
2021/12/16
ApexBio Technology
Product number
B5119
Product name
OrexinB(mouse)
Packaging
1mg
Price
$536
Updated
2021/12/16
ChemScene
Product number
CS-0029470
Product name
OrexinB,rat,mouse
Packaging
5mg
Price
$1150
Updated
2021/12/16
ApexBio Technology
Product number
B5119
Product name
OrexinB(mouse)
Packaging
5mg
Price
$2048
Updated
2021/12/16
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H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2 Chemical Properties,Usage,Production

Uses

Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.

Biological Activity

Orexin B (mouse) is an endogenous agonist of the Orexin receptor with Ki values of 420 and 36 nM for OX1 and OX2, respectively.

in vivo

Orexin-B modulates the activity of rod bipolar cells (RBCs) located in the outer retina of rat. Intravitreal injection of orexin-B increased the amplitude of the scotopic electroretinographic b-wave, a reflection of RBC activity, recorded in vivo[4].

target

Ki: 420 nM (OX1), 36 nM (OX2)

IC 50

OX2 Receptor

storage

-20°C

References

[1] Smart D, et al. Orexins: a new family of neuropeptides. Br J Anaesth. 1999 Nov;83(5):695-7. DOI:10.1093/bja/83.5.695
[2] Sakurai T, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998 Feb 20;92(4):573-85. DOI:10.1016/s0092-8674(00)80949-6
[3] Ziolkowska A, et al. Orexin B inhibits proliferation and stimulates specialized function of cultured rat calvarial osteoblast-like cells. Int J Mol Med. 2008;22(6):749-755. PMID:19020772
[4] Zhang G, et al. Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina. Neuropharmacology. 2018;133:38-50. DOI:10.1016/j.neuropharm.2018.01.007

H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2 Suppliers

China 88 France 1 Germany 4 Japan 1 Switzerland 2 United Kingdom 1 United States 11 USA 1 Global 109
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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15838
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GL Biochem (Shanghai) Ltd
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21-61263452 13641803416
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86-21-61263399
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ymbetter@glbiochem.com
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China
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9981
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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42934
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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32321
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50
Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
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ivy@hnhbsj.com
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China
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7247
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62
Cellmano Biotech Limited
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0551-65326643 18156095617
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0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1010
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
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60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
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80
Creative Peptides
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Email
info@creative-peptides.com
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United States
ProdList
6083
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56
Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
Country
China
ProdList
71826
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60
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View Lastest Price from H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2 manufacturers

Career Henan Chemical Co
Product
H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2 202801-92-1
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

202801-92-1, H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2Related Search:

PHENYLSELENOL N-BUTYLISOCYANIDE TERT-BUTYL ISOCYANIDE 2,4-PENTANEDIONE, SILVER DERIVATIVE SALCOMINE COBALT(II) ACETYLACETONATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tosylmethyl isocyanide METHYL ISOCYANOACETATE Benzyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Ferric acetylacetonate Cupric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Ethyl isocyanoacetate Aluminum acetylacetonate

  • ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • HYPOCRETIN-B, MOUSE
  • H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • OREXIN B (MOUSE)
  • OREXIN B (MOUSE, RAT)
  • OREXIN B (RAT, MOUSE)
  • OREXINS OREXIN B RAT, MOUSE
  • RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2
  • OREXIN-B (RAT, HUMAN)
  • Orexin B (Mouse, rat) Hypocretin-2 (Mouse, rat)
  • Hypocretin-2 (Mouse, rat)
  • ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG- LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • REF DUPL: H-Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
  • Orexin B (rat, mouse), ≥97% (HPLC)
  • Rat orexin B
  • L-Methioninamide, L-arginyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-asparaginylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl- (9CI)
  • H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2 USP/EP/BP
  • Orexin B, mouse/rat - 1 mg
  • 202801-92-1
  • C126H215N45O34S
  • C126H215N45O34S1
  • Orexin receptor
  • Peptide