2,4-Dichloro-6-methoxy-1,3,5-triazine
- Product Name
- 2,4-Dichloro-6-methoxy-1,3,5-triazine
- CAS No.
- 3638-04-8
- Chemical Name
- 2,4-Dichloro-6-methoxy-1,3,5-triazine
- Synonyms
- DCMT;Dichloromethoxytriazine;METHOXYDICHLOROTRIAZINE;oro-6-methoxy-1,3,5-triazine;2,4-dichloro-6-methoxy-s-triazine;4,6-Dichloro-2-methoxy-s-triazine;2-Methoxy-4,6-dichloro-1,3,5-triazine;2,4-DICHLORO-6-METHOXY-1,3,5-TRIAZINE;1,3,5-Triazine, 2,4-dichloro-6-methoxy-;2,4-DICHLORO-6-METHOXY-1,3,5-TRIAZINE, 9 5+%
- CBNumber
- CB6335179
- Molecular Formula
- C4H3Cl2N3O
- Formula Weight
- 179.99
- MOL File
- 3638-04-8.mol
2,4-Dichloro-6-methoxy-1,3,5-triazine Property
- Melting point:
- 86-88 °C (lit.)
- Boiling point:
- 132-134 °C/49 mmHg (lit.)
- Density
- 1.538±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -1.40±0.10(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 3638-04-8(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 213535
- Product name
- 2,4-Dichloro-6-methoxy-1,3,5-triazine
- Packaging
- 1g
- Price
- $35.4
- Updated
- 2025/07/31
- Product number
- 213535
- Product name
- 2,4-Dichloro-6-methoxy-1,3,5-triazine
- Packaging
- 5g
- Price
- $168
- Updated
- 2025/07/31
- Product number
- D3747
- Product name
- 2,4-Dichloro-6-methoxy-1,3,5-triazine
- Packaging
- 1G
- Price
- $60
- Updated
- 2025/07/31
- Product number
- D3747
- Product name
- 2,4-Dichloro-6-methoxy-1,3,5-triazine
- Packaging
- 5G
- Price
- $181
- Updated
- 2025/07/31
- Product number
- D435290
- Product name
- 2,4-Dichloro-6-methoxy-1,3,5-triazine
- Packaging
- 1g
- Price
- $65
- Updated
- 2021/12/16
2,4-Dichloro-6-methoxy-1,3,5-triazine Chemical Properties,Usage,Production
Uses
2,4-Dichloro-6-methoxy-1,3,5-triazine was used as reagent in radioimmunoassay for D-Ala2-Dermorphin, a natural peptide extracted from amphibian skin. It was also used in the preparation of:
- α-cyclodextrin [2]-rotaxanes
- substituted s-triazines
- series of chiral derivatizing reagents
Synthesis
67-56-1
108-77-0
3638-04-8
(3) Synthesis of intermediate (2,4-dichloro-6-methoxy-1,3,5-triazine): 136 mL of deionized water was added to 1.1 L of methanol, followed by the addition of 182 g (2.17 mol) of sodium bicarbonate, and stirred at room temperature until completely dissolved. At the same temperature, 200 g (1.08 mol) of cyanuric chloride was added in batches. After the addition was completed, the temperature was slowly raised to 30°C and stirred continuously at this temperature for 30 minutes. Upon completion of the reaction, the reaction was quenched by the addition of 500 mL of deionized water and the precipitated solid product was collected by filtration. The solid was washed with 500 mL of deionized water and subsequently recrystallized with 300 mL of methanol and dried to give 168 g of intermediate (2,4-dichloro-6-methoxy-1,3,5-triazine) (white powder, 86.2% yield). The nuclear magnetic resonance hydrogen spectrum (1H-NMR, 300 MHz, CDCl3) data of the obtained product were as follows: δ 4.14 (s, 3H).
References
[1] Heterocycles, 2009, vol. 79, # C, p. 609 - 616
[2] Journal of Organic Chemistry, 2011, vol. 76, # 6, p. 1804 - 1813
[3] Molecules, 2016, vol. 21, # 6,
[4] Patent: WO2010/104210, 2010, A1. Location in patent: Page/Page column 36; 38
[5] Patent: EP2230278, 2010, A2. Location in patent: Page/Page column 33
2,4-Dichloro-6-methoxy-1,3,5-triazine Preparation Products And Raw materials
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View Lastest Price from 2,4-Dichloro-6-methoxy-1,3,5-triazine manufacturers
- Product
- 2,4-Dichloro-6-methoxy-1,3,5-triazine 3638-04-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-17
- Product
- 2,4-Dichloro-6-methoxy-1,3,5-triazine 3638-04-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20t
- Release date
- 2024-07-15
- Product
- 2,4-Dichloro-6-methoxy-1,3,5-triazine 3638-04-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 25kg
- Release date
- 2019-07-11