ChemicalBook > CAS DataBase List > 2,4-Dichloro-6-methoxy-1,3,5-triazine

2,4-Dichloro-6-methoxy-1,3,5-triazine

Product Name
2,4-Dichloro-6-methoxy-1,3,5-triazine
CAS No.
3638-04-8
Chemical Name
2,4-Dichloro-6-methoxy-1,3,5-triazine
Synonyms
DCMT;Dichloromethoxytriazine;METHOXYDICHLOROTRIAZINE;oro-6-methoxy-1,3,5-triazine;2,4-dichloro-6-methoxy-s-triazine;4,6-Dichloro-2-methoxy-s-triazine;2-Methoxy-4,6-dichloro-1,3,5-triazine;2,4-DICHLORO-6-METHOXY-1,3,5-TRIAZINE;1,3,5-Triazine, 2,4-dichloro-6-methoxy-;2,4-DICHLORO-6-METHOXY-1,3,5-TRIAZINE, 9 5+%
CBNumber
CB6335179
Molecular Formula
C4H3Cl2N3O
Formula Weight
179.99
MOL File
3638-04-8.mol
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2,4-Dichloro-6-methoxy-1,3,5-triazine Property

Melting point:
86-88 °C (lit.)
Boiling point:
132-134 °C/49 mmHg (lit.)
Density 
1.538±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.40±0.10(Predicted)
Appearance
White to off-white Solid
CAS DataBase Reference
3638-04-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
RIDADR 
UN 3335
WGK Germany 
3
HS Code 
2933698090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
213535
Product name
2,4-Dichloro-6-methoxy-1,3,5-triazine
Packaging
1g
Price
$35.4
Updated
2025/07/31
Sigma-Aldrich
Product number
213535
Product name
2,4-Dichloro-6-methoxy-1,3,5-triazine
Packaging
5g
Price
$168
Updated
2025/07/31
TCI Chemical
Product number
D3747
Product name
2,4-Dichloro-6-methoxy-1,3,5-triazine
Packaging
1G
Price
$60
Updated
2025/07/31
TCI Chemical
Product number
D3747
Product name
2,4-Dichloro-6-methoxy-1,3,5-triazine
Packaging
5G
Price
$181
Updated
2025/07/31
TRC
Product number
D435290
Product name
2,4-Dichloro-6-methoxy-1,3,5-triazine
Packaging
1g
Price
$65
Updated
2021/12/16
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2,4-Dichloro-6-methoxy-1,3,5-triazine Chemical Properties,Usage,Production

Uses

2,4-Dichloro-6-methoxy-1,3,5-triazine was used as reagent in radioimmunoassay for D-Ala2-Dermorphin, a natural peptide extracted from amphibian skin. It was also used in the preparation of:

  • α-cyclodextrin [2]-rotaxanes
  • substituted s-triazines
  • series of chiral derivatizing reagents

Synthesis

67-56-1

108-77-0

3638-04-8

(3) Synthesis of intermediate (2,4-dichloro-6-methoxy-1,3,5-triazine): 136 mL of deionized water was added to 1.1 L of methanol, followed by the addition of 182 g (2.17 mol) of sodium bicarbonate, and stirred at room temperature until completely dissolved. At the same temperature, 200 g (1.08 mol) of cyanuric chloride was added in batches. After the addition was completed, the temperature was slowly raised to 30°C and stirred continuously at this temperature for 30 minutes. Upon completion of the reaction, the reaction was quenched by the addition of 500 mL of deionized water and the precipitated solid product was collected by filtration. The solid was washed with 500 mL of deionized water and subsequently recrystallized with 300 mL of methanol and dried to give 168 g of intermediate (2,4-dichloro-6-methoxy-1,3,5-triazine) (white powder, 86.2% yield). The nuclear magnetic resonance hydrogen spectrum (1H-NMR, 300 MHz, CDCl3) data of the obtained product were as follows: δ 4.14 (s, 3H).

References

[1] Heterocycles, 2009, vol. 79, # C, p. 609 - 616
[2] Journal of Organic Chemistry, 2011, vol. 76, # 6, p. 1804 - 1813
[3] Molecules, 2016, vol. 21, # 6,
[4] Patent: WO2010/104210, 2010, A1. Location in patent: Page/Page column 36; 38
[5] Patent: EP2230278, 2010, A2. Location in patent: Page/Page column 33

2,4-Dichloro-6-methoxy-1,3,5-triazine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,4-Dichloro-6-methoxy-1,3,5-triazine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2,4-Dichloro-6-methoxy-1,3,5-triazine 3638-04-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-17
Shaanxi Dideu Medichem Co. Ltd
Product
2,4-Dichloro-6-methoxy-1,3,5-triazine 3638-04-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20t
Release date
2024-07-15
Career Henan Chemical Co
Product
2,4-Dichloro-6-methoxy-1,3,5-triazine 3638-04-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-11

3638-04-8, 2,4-Dichloro-6-methoxy-1,3,5-triazineRelated Search:


  • 2,4-DICHLORO-6-METHOXY-1,3,5-TRIAZINE
  • DCMT
  • 2-Methoxy-4,6-dichloro-1,3,5-triazine
  • 4,6-Dichloro-2-methoxy-s-triazine
  • 2,4-dichloro-6-methoxy-s-triazine
  • METHOXYDICHLOROTRIAZINE
  • 2,4-DICHLORO-6-METHOXY-1,3,5-TRIAZINE, 9 5+%
  • 2, 4-DICHLORO-6-METHOXY-1, 3, 5-TRIAZINE (DCMT)
  • Dichloromethoxytriazine
  • oro-6-methoxy-1,3,5-triazine
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