ChemicalBook > CAS DataBase List > 2-Amino-4,6-dihydroxypyrimidine

2-Amino-4,6-dihydroxypyrimidine

Product Name
2-Amino-4,6-dihydroxypyrimidine
CAS No.
56-09-7
Chemical Name
2-Amino-4,6-dihydroxypyrimidine
Synonyms
2-AMINOPYRIMIDINE-4,6-DIOL;2-amino-6-hydroxy-1h-pyrimidin-4-one;4(3H)-Pyrimidinone, 2-amino-6-hydroxy-;2-ADHP;NSC 18692;NSC 15920;AKOS 92830;AKOS BBS-00007961;TIMTEC-BB SBB004247;6-dihydroxypyriMidine
CBNumber
CB6342676
Molecular Formula
C4H5N3O2
Formula Weight
127.1
MOL File
56-09-7.mol
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2-Amino-4,6-dihydroxypyrimidine Property

Melting point:
>300 °C (lit.)
Boiling point:
235.85°C (rough estimate)
Density 
1.4748 (rough estimate)
refractive index 
1.5000 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Soluble in Aqueous Alkali.
pka
7.45±0.10(Predicted)
form 
Powder
color 
Off-white to light pink or light yellow
BRN 
510297
InChI
InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)
InChIKey
AUFJTVGCSJNQIF-UHFFFAOYSA-N
SMILES
C1(N)=NC(O)=CC(=O)N1
CAS DataBase Reference
56-09-7(CAS DataBase Reference)
EPA Substance Registry System
2-Amino-6-hydroxy-4(1H)-pyrimidinone (56-09-7)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
1
RTECS 
UW7361000
TSCA 
Yes
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A50401
Product name
2-Amino-4,6-dihydroxypyrimidine
Purity
98%
Packaging
25g
Price
$250
Updated
2025/07/31
Sigma-Aldrich
Product number
A50401
Product name
2-Amino-4,6-dihydroxypyrimidine
Purity
98%
Packaging
100g
Price
$666.4
Updated
2025/07/31
TCI Chemical
Product number
A1099
Product name
2-Amino-4,6-dihydroxypyrimidine
Purity
>98.0%(HPLC)
Packaging
25g
Price
$37
Updated
2025/07/31
TRC
Product number
A604930
Product name
2-Amino-4,6-dihydroxypyrimidine
Packaging
25g
Price
$55
Updated
2021/12/16
TRC
Product number
A604930
Product name
2-Amino-4,6-dihydroxypyrimidine
Packaging
100g
Price
$125
Updated
2021/12/16
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2-Amino-4,6-dihydroxypyrimidine Chemical Properties,Usage,Production

Description

2-Amino-4,6-dihydroxypyrimidine is a hydroxypyrimidine.

Chemical Properties

White Solid

Uses

2-Amino-4,6-dihydroxypyrimidine acts as an intermediate in the production of antimicrobial guanylsulfonamides. It also acts as an intermediate in pharmaceuticals and agrochemicals.

Definition

ChEBI: 2-Amino-4,6-dihydroxypyrimidine is a hydroxypyrimidine.

Synthesis

The synthesis of 2-Amino-4,6-dihydroxypyrimidine is as follows:
A freshly-prepared sodiummethoxide solution in methanol (25 ml) was added to a round-bottomed flask containing guanidine hydrochloride(15 mmol), stirred for a few minutes, before dimethyl malonate (15 mmol)was slowly added. The mixture was heated under reflux for about 2-3hours. After evaporation of the solvent under reduced pressure, the resultingwhite solid was dissolved in a minimum amount of water and the pH adjusted to 6with 10% HCl. The precipitate obtained was filtered and washed with distilledwater and ethanol, respectively, to obtain pure 2-amino-4,6-pyrimidinediol.(Note: sodium methoxide solution was prepared by addition of small pieces ofsodium metal in methanol).Yield: 85%;solid, m.p. 195-197 °C.

References

[1] Patent: CN106167469, 2016, A. Location in patent: Paragraph 0012; 0013; 0014

2-Amino-4,6-dihydroxypyrimidine Preparation Products And Raw materials

Raw materials

Sodium ethoxide Guanidine nitrate

Preparation Products

2,5-Diamino-4,6-dichloropyrimidine Bensulfuron methyl 2,5-Diamino-4,6-dihydroxy-pyrimidine 2-Amino-4,6-dimethoxypyrimidine
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View Lastest Price from 2-Amino-4,6-dihydroxypyrimidine manufacturers

Dideu Industries Group Limited
Product
2-Amino-4,6-dihydroxypyrimidine 56-09-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-09
Hebei Miaobian Biotechnology Co., Ltd
Product
2-Amino-4,6-dihydmidine 56-09-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99.99
Supply Ability
10Ton
Release date
2020-12-18
Career Henan Chemical Co
Product
2-Amino-4,6-dihydroxypyrimidine 56-09-7
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10tons
Release date
2018-12-23

56-09-7, 2-Amino-4,6-dihydroxypyrimidineRelated Search:

1-Hydroxyethylidene-1,1-diphosphonic acid Iminodiacetonitrile Isocytosine CHLOROPHOSPHONAZO III 3-Aminophenol ALTRENOGEST 2-Amino-4,6-dichloropyrimidine 1,3-Dihydroxyacetone 6-Aminocaproic acid 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL Triclosan 4,4'-Methylenedianiline 4,6-Diaminopyrimidine 2-Amino-5-hydroxypyrimidine Glycine 2-Aminopyrimidine Tris(hydroxymethyl)aminomethane 4,6-Dihydroxypyrimidine

  • 2-amino-6-hydroxy-4(1h)-pyrimidinon
  • 2-amino-6-hydroxy-4(1H)-Pyrimidinone
  • 2-AMino-4,6-dioxypyriMidine
  • 2-AMino-6-hydroxy-4(3H)-pyriMidinone
  • NSC 15920
  • NSC 18692
  • 2-aMino-6-hydroxypyriMidin-4(3H)-one
  • 2-AMino-4,6-dihydroxypyriMidine, 97+%
  • 2-Amino-6-hydroxypyrimidin-4(3H)
  • TIMTEC-BB SBB004247
  • 2-AMINOPYRIMIDINE-4,6-DIOL
  • 2-AMINO-4,6-PYRIMIDINEDIOL
  • 2-AMINO-4,6-DIHYDROXYPYRIMIDINE
  • 2-amino-6-hydroxy-1h-pyrimidin-4-one
  • 2-ADHP
  • 2 - aMino - 4, 6-2 hydroxy pyriMidine
  • 4(1H)-PYRIMIDINONE, 2-AMINO-6-HYDROXY-
  • AKOS BBS-00007961
  • AKOS 92830
  • LABOTEST-BB LT00080685
  • 4(1H)-Pyrimidinone, 2-amino-6-hydroxy- (8CI,9CI)
  • 2-Amino-6-hydroxy-1H-pyrimidin-4-on
  • 2-Amino-6-hydroxy-3H-pyrimidin-4-one
  • 2-Amino-4,6-dihydroxypyrimidine,98%
  • 2-Amino-3,4-dihydro-6-hydroxypyrimidine-4-one
  • 2-Amino-6-hydroxypyrimidin-4(1H)-one
  • 4,6-Dihydroxy-2-aminopyrimidine
  • 6-dihydroxypyriMidine
  • 2-AMino-4,6-dihydroxypyriMidine, 98% 100GR
  • 2-AMino-4,6-dihydroxypyriMidine, 98% 25GR
  • 2-Amino-4,6-dihydroxypyrimidine &gt
  • 2-Amino-4,6-dihydmidine
  • 4(3H)-Pyrimidinone, 2-amino-6-hydroxy-
  • 2-Amino-4,6-dihydroxypyrimidine ISO 9001：2015 REACH
  • 2-amino-4-hydroxy-1H-pyrimidin-6-one
  • 56-09-7
  • 1965-09-7
  • 1956-0'9-7
  • 1956-09-07
  • 1956-09-7
  • 20-70-5
  • 1508-62-5
  • C4H5N3O2
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrimidines
  • Amines
  • Aromatics
  • Heterocycles
  • 5-FOA
  • Bases & Related Reagents
  • Nucleotides
  • Nucleotides and Nucleosides
  • Pyrimidines
  • PYRIMIDINE
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Heterocycle-Pyrimidine series