2,2,5,7,8-PENTAMETHYL-6-CHROMANOL

Product Name: 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL
CAS No.: 950-99-2
Chemical Name: 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL
Synonyms: APC-100;Chromanol C1;Chromane C-1;PROTOPANAXATRIOL(RG);2,2,5,7,8-PENTAMETHYL-6-CHROMANOL;2,2,5,7,8-pentamethylchroman-6-ol;2,2,5,7,8-Pentamethyl-6-chromanol 97%;2,2,5,7,8-pentamethyl-1-hydroxychroman;6-Hydroxy-2,2,5,7,8-pentamethylchroman;2,2,5,7,8-Pentamethyl-6-chromanolTMC-5
CBNumber: CB6350963
Molecular Formula: C14H20O2
Formula Weight: 220.31
MOL File: 950-99-2.mol

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2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Property

Melting point:: 89-91 °C (lit.)
Boiling point:: 344.3±42.0 °C(Predicted)
Density: 1.034±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 250 mg/mL (1134.76 mM)
form: solid
pka: 11.41±0.40(Predicted)
color: White

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 430676
Product name: 2,2,5,7,8-Pentamethyl-6-chromanol
Purity: 97%
Packaging: 5g
Price: $72.01
Updated: 2025/07/31

Sigma-Aldrich

Product number: 430676
Product name: 2,2,5,7,8-Pentamethyl-6-chromanol
Purity: 97%
Packaging: 25g
Price: $281
Updated: 2025/07/31

AK Scientific

Product number: 0723AQ
Product name: 2,2,5,7,8-Pentamethyl-6-chromanol
Packaging: 5g
Price: $127
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0007468
Product name: 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL
Purity: 95.00%
Packaging: 1G
Price: $628.68
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0007468
Product name: 2,2,5,7,8-PENTAMETHYL-6-CHROMANOL
Purity: 95.00%
Packaging: 5G
Price: $869.55
Updated: 2021/12/16

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2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Chemical Properties,Usage,Production

Uses

2,2,5,7,8-Pentamethyl-6-chromanol is the suitable reagent used for the quantitative analysis of α-tocopherol by plasma-based gas chromatography/tandem mass spectrometry (GC/MS/MS) using a tabletop quadrupole ion trap mass spectrometer. It may be employed as α-tocopherol model compound and on oxidation by t-butyl hydroperoxide in chloroform, in the presence of alcohol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanol. It may be used as internal standard for the determination of α- and γ-tocopherol in the rabbit serum and liver by HPLC.

General Description

2,2,5,7,8-Pentamethyl-6-chromanol has been reported as an vitamin E model compound. It undergoes oxidation in presence of various alcohols, ranging from methanol to cholesterol, affords 5-alkoxymethyl-2,2,7,8-tetramethyl-6-chromanols. Antioxidant moiety of vitamin E, 2,2,5,7,8-pentamethyl-6-chromanol (PMCol), is reported to have antiandrogen activity in prostate carcinoma cells.

2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2,5,7,8-PENTAMETHYL-6-CHROMANOL Suppliers

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950-99-2, 2,2,5,7,8-PENTAMETHYL-6-CHROMANOLRelated Search:

2,2,5,7,8-PENTAMETHYL-6-CHROMANOL DL-ALPHA-TOCOPHEROL HYDROGEN SUCCINATE Vitamin E 2,2,5,7,8-PENTAMETHYLCHROMAN Vitamin E nicotinate Trolox DL-α-Tocopherol D-alpha-Tocopheryl acetate DL-ALPHA-TOCOPHEROL ACETATE D-α-Tocopherol succinate Vitamin E (R)-(+)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID (R)-6-METHOXY-2,5,7,8-TETRAMETHYLCHROMANE-2-CARBOXYLIC ACID (S)-(-)-6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID (+/-)-ALPHA-TOCOPHEROL PHOSPHATE DISODIUM SALT (S)-6-METHOXY-2,5,7,8-TETRAMETHYLCHROMANE-2-CARBOXYLIC ACID Tocofenoxate TOCORRETINATE

2,2,5,7,8-pentamethyl-1-hydroxychroman

3,4-dihydro-2,2,5,7,8-pentamethyl-2H-1-Benzopyran-6-ol

2,2,5,7,8-PENTAMETHYL-6-CHROMANOL

2,2,5,7,8-PENTAMETHYL-6-HYDROXYCHROMAN

2,2,5,7,8-Pentamethyl-6-chromanolTMC-5

6-Hydroxy-2,2,5,7,8-pentamethylchroman

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2,2,5,7,8-pentamethyl-3,4-dihydrochromen-6-ol

2,2,5,7,8-pentamethylchroman-6-ol

PROTOPANAXATRIOL(RG)

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2,2,5,7,8-Pentamethyl-6-chromanol 97%

2H-1-Benzopyran-6-ol, 3,4-dihydro-2,2,5,7,8-pentamethyl-

inhibit,2,2,5,7,8 Pentamethyl 6 Chromanol,Androgen Receptor,Inhibitor,2,2,5,7,8Pentamethyl6Chromanol

PENTAMETHYL-6-HYDROXYCHROMAN, 2,2,5,7,8-

2,2,5,7,8-Pentamethyl-6-Chromanol, 10 mM in DMSO

950-99-2

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