Felodipine

Product Name: Felodipine
CAS No.: 86189-69-7
Chemical Name: Felodipine
Synonyms: FLODIL;FELODAY;Agon sr;Perfuda;Perfudal;Felodipina;Felodipine;Brn 4331472;Felodipine Imp;Felodipine iMpurity
CBNumber: CB6411200
Molecular Formula: C18H19Cl2NO4
Formula Weight: 384.25
MOL File: 86189-69-7.mol

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Felodipine Property

solubility: DMSO: 28 mg/mL
form: solid
color: light yellow
BCS Class: 2
CAS DataBase Reference: 86189-69-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: US7968700

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Hazard and Precautionary Statements (GHS)

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Felodipine Chemical Properties,Usage,Production

Uses

Vasodilator.

brand name

Plendil (AstraZeneca).

Clinical Use

Calcium-channel blocker:
Hypertension
Angina

Drug interactions

Potentially hazardous interactions with other drugs
Aminophylline and theophylline: possibly increased aminophylline and theophylline concentration.
Anaesthetics: enhanced hypotensive effect.
Antibacterials metabolism possibly inhibited by clarithromycin, erythromycin and telithromycin.
Antidepressants: enhanced hypotensive effect with MAOIs.
Antiepileptics: effect reduced by carbamazepine, barbiturates, phenytoin and primidone.
Antifungals: metabolism inhibited by itraconazole and ketoconazole; negative inotropic effect possibly increased with itraconazole.
Antihypertensives: enhanced hypotensive effect, increased risk of first dose hypotensive effect of postsynaptic alpha-blockers.
Antivirals: concentration possibly increased by ritonavir; use with caution with telaprevir.
Grapefruit juice: concentration increased - avoid concomitant use.
Tacrolimus: possibly increased tacrolimus concentration

Metabolism

Felodipine is metabolised in the liver and all identified metabolites are devoid of vasodilating properties. Approximately 70% of a given dose is excreted as metabolites in the urine and about 10% with the faeces. Less than 0.5% of the dose is excreted unchanged in the urin

Felodipine Preparation Products And Raw materials

Raw materials

Preparation Products

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Felodipine Suppliers

Canada 3 China 145 China Hong Kong 1 France 2 Germany 1 India 19 Mexico 1 Spain 3 Sweden 1 Switzerland 1 The Netherlands 1 United Kingdom 3 United States 20 Global 201

Zhejiang Supor Pharmaceuticals Co., Ltd

Tel: 0575-89185560
Fax: 0086-571-87810356
Email: chencx@suporpharm.com
Country: China
ProdList: 68
Advantage: 66

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4496
Advantage: 50

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1493
Advantage: 55

China Nobel Chem Co., Limited

Tel: +86(0)21 60484900
Fax: +86(0)21 60484900
Country: China
ProdList: 764
Advantage: 50

Shenzhen DaerSen Science and Technology Co., Ltd.

Tel: 0755-84551027
Fax: 0755-61605162
Country: China
ProdList: 220
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

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View Lastest Price from Felodipine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: FELODIPINE 86189-69-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Hebei shuoxi biotechnology co. LTD

Product: 5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 86189-69-7
Price: US $60.00/KG
Min. Order: 10g
Purity: 99.8%
Supply Ability: 10tons
Release date: 2019-11-01

Career Henan Chemical Co

Product: Felodipine 86189-69-7
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-17

86189-69-7, FelodipineRelated Search:

Poly(dimethylsiloxane) Dimethyl fumarate Dimethyl sulfoxide Dimethyl sulfate Dichlorodimethylsilane Dimethyl ether Dimethyl carbonate N,N-Dimethylacetamide ETHANE Chlorodimethylphenylsilane Dichlorodiphenylsilane N,N-Dimethylformamide Methyl FELODIPINE IMP.C ( EP) :DIETHYL-4-(2,3-DICHLOROPHENYL)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE Methyl bromide FELODIPINE IMP.A ( EP) :ETHYL METHYL-4-(2,3-DICHLOROPHENYL)-2,6-DIMETHYLPYRIDINE-3,5-DICARBOXYLATE Bicalutamide (RS)-Felodipine,dl-Felodipine,Felodipine

4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINECARBOXYLIC ACID METHYL ESTER

4-(2,3-DICHLOROPHENYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID METHYL ESTER

FLODIL

FELODAY

ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Agon sr

Brn 4331472

Felodipina

3-ethyl 5-Methyl (4R)-4-(2,3-dichlorophenyl)-2,6-diMethyl-1,4-dihydropyridine-3,5-dicarboxylate

Felodipine iMpurity

Felodipine Imp

Felodipine

5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Perfuda

Perfudal

5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1

Felodipine Powder USP Standard

86189-69-7

Cell Biology

Cell Signaling and Neuroscience

Calcium Channel Modulators

BioChemical

Inhibitors and Activators

Ion Channels

Voltage-gated Ion Channels