ChemicalBook > CAS DataBase List > Tetrahydrofurfuryl alcohol

Tetrahydrofurfuryl alcohol

Product Name
Tetrahydrofurfuryl alcohol
CAS No.
97-99-4
Chemical Name
Tetrahydrofurfuryl alcohol
Synonyms
THFA;Tetrahydrofurfuryl;TETRAHYDRO-2-FURANMETHANOL;Oxolane-2-methanol;2-Hydroxymethyl oxolane;Tetrahydrofuran methanol;Tetrahydro-2-furylmethanol;Tetrahydrofurfruyl Alcohol;(tetrahydro-furan-2-yl)-methanol;qothfa
CBNumber
CB6414751
Molecular Formula
C5H10O2
Formula Weight
102.13
MOL File
97-99-4.mol
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Tetrahydrofurfuryl alcohol Property

Melting point:
-80 °C (lit.)
Boiling point:
178 °C (lit.)
Density 
1.054 g/mL at 25 °C (lit.)
vapor density 
3.52 (vs air)
vapor pressure 
2.3 mm Hg ( 39 °C)
refractive index 
n20/D 1.452(lit.)
FEMA 
3056 | TETRAHYDROFURFURYL ALCOHOL
Flash point:
183 °F
storage temp. 
Store below +30°C.
solubility 
acetone: miscible(lit.)
form 
Liquid
pka
14.44±0.10(Predicted)
color 
Clear
Odor
at 100.00 %. vegetable cauliflower faint warm oily caramel
Odor Type
vegetable
explosive limit
1.5-9.7%(V)
Water Solubility 
soluble
Sensitive 
Hygroscopic
Merck 
14,9213
JECFA Number
1443
BRN 
102723
Dielectric constant
13.48
InChIKey
BSYVTEYKTMYBMK-UHFFFAOYSA-N
LogP
-0.14 at 24.7℃
CAS DataBase Reference
97-99-4(CAS DataBase Reference)
NIST Chemistry Reference
2-Furanmethanol, tetrahydro-(97-99-4)
EPA Substance Registry System
Tetrahydrofurfuryl alcohol (97-99-4)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36-62-61
Safety Statements 
39-36/37/39
RIDADR 
NA 1993 / PGIII
WGK Germany 
2
RTECS 
LU2450000
Autoignition Temperature
282 °C
TSCA 
Yes
HS Code 
29321300
Hazardous Substances Data
97-99-4(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1600 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W305618
Product name
Tetrahydrofurfuryl alcohol
Purity
≥98%
Packaging
1kg
Price
$67.8
Updated
2024/03/01
Sigma-Aldrich
Product number
W305618
Product name
Tetrahydrofurfuryl alcohol
Purity
≥98%
Packaging
10Kg
Price
$298
Updated
2024/03/01
Sigma-Aldrich
Product number
W305618
Product name
Tetrahydrofurfuryl alcohol
Purity
≥98%
Packaging
25kg
Price
$642
Updated
2024/03/01
Sigma-Aldrich
Product number
8.22307
Product name
Tetrahydrofurfuryl alcohol
Purity
for synthesis
Packaging
1L
Price
$45
Updated
2024/03/01
Sigma-Aldrich
Product number
185396
Product name
Tetrahydrofurfuryl alcohol
Purity
99%
Packaging
5g
Price
$17.22
Updated
2024/03/01
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Tetrahydrofurfuryl alcohol Chemical Properties,Usage,Production

Chemical Properties

Tetrahydrofurfuryl alcohol is a colorless to light yellow hygroscopic liquid that has a faint, warm, oily, caramellic odor with a coffee and nut-like flavor at very low levels (0.03 to 1 ppm). Miscible with water, ethanol, ether, acetone, chloroform and benzene, insoluble in paraffin hydrocarbons. It has an extensive history of use as a highly versatile, high purity solvent.

Occurrence

Reported found in shoyu (fermented soya hydrolysate), coffee and fresh mango.

Uses

Tetrahydrofurfuryl alcohol is used extensively in various industries as a high-purity, water miscible solvent, and as a chemical intermediate. It was used as Solvent for vinyl resins; dyes for leather; chlorinated rubber; cellulose esters; solvent softener for nylon; vegetable oils; coupling agent; organic synthesis.

Definition

ChEBI: Tetrahydrofurfuryl alcohol is a primary alcohol that is methanol in which one of the hydrogens of the methyl group has been replaced by a tetrahydrofuran-2-yl group. It has a role as a protic solvent. It is a primary alcohol and a member of oxolanes.

Application

Tetrahydrofurfuryl alcohol (THFA) is generally regarded as a "green" solvent in industrial applications. THFA is a low cost, biodegradable solvent mainly used as a reactive diluent for epoxy resins and is a good solvent for many of the curative and catalysts used in epoxy formulations. It is also used in the following applications:
Tetrahydrofurfuryl alcohol undergoes chemoselective hydrogenolysis catalyzed by Rh/SiO2 modified with ReOx species to yield 1,5-pentanediol. It undergoes lanthanum-mediated Michael-type addition reaction with maleate to form alkoxybutanedioic acid.
Tetrahydrofurfuryl alcohol was used as refractive-index matching solvent to ensure hard sphere suspension of silica particles for rheological measurements.
Tetrahydrofurfuryl alcohol may be used as an analytical reference standard for the quantification of the analyte in rats and smoke flavoring from rice husk using chromatography techniques.

Preparation

Tetrahydrofurfuryl alcohol is produced by catalytic reduction of furfural with Raney-Ni; also by destructive hydrogenation of lignin.

General Description

Tetrahydrofurfuryl alcohol appears as a clear colorless liquid with a mild odor. Vapors are heavier than air.

Air & Water Reactions

Denser than water and soluble in water.

Reactivity Profile

Acetyl bromide reacts violently with alcohols or water [Merck 11th ed. 1989]. Mixtures of alcohols with concentrated sulfuric acid and strong hydrogen peroxide can cause explosions. Example: An explosion will occur if dimethylbenzylcarbinol is added to 90% hydrogen peroxide then acidified with concentrated sulfuric acid. Mixtures of ethyl alcohol with concentrated hydrogen peroxide form powerful explosives. Mixtures of hydrogen peroxide and 1-phenyl-2-methyl propyl alcohol tend to explode if acidified with 70% sulfuric acid [Chem. Eng. News 45(43):73. 1967; J, Org. Chem. 28:1893. 1963]. Alkyl hypochlorites are violently explosive. They are readily obtained by reacting hypochlorous acid and alcohols either in aqueous solution or mixed aqueous- carbon tetrachloride solutions. Chlorine plus alcohols would similarly yield alkyl hypochlorites. They decompose in the cold and explode on exposure to sunlight or heat. Tertiary hypochlorites are less unstable than secondary or primary hypochlorites [NFPA 491 M 1991]. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence [Wischmeyer 1969].

Health Hazard

Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Flammability and Explosibility

Not classified

Carcinogenicity

Tetrahydro-2-furanmethanol was not mutagenic to S. typhimurium strains TA100, TA1535, TA1537, or TA98 in an in vitro gene mutation assay or to E. coliWP2uvrA/pKM101 with or withoutmetabolic activation. No chromosomal aberrations or polypoidy were observed when tetrahydro-2-furanmethanol was added to cultured Chinese hamster lung cells with or without metabolic activation .

Tetrahydrofurfuryl alcohol Preparation Products And Raw materials

Raw materials

Hydrogen Furfuryl alcohol Furfural

Preparation Products

1-TETRAHYDROFURFURYL-PIPERAZINE Tetrahydrofurfuryl bromide (R)-(+)-Tetrahydro-2-furoic acid 2-(Aminomethyl)-1-ethylpyrrolidine 3,4-Dihydro-2H-pyran Tetrahydrofurfuryl chloride 1,5-Pentanediol TETRAHYDROFURFURYL ACETATE Deflazacort
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View Lastest Price from Tetrahydrofurfuryl alcohol manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
Tetrahydrofurfuryl alcoho 97-99-4
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-07
Hebei Longbang Technology Co., Ltd
Product
Tetrahydrofurfuryl alcohol 97-99-4
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-29
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Tetrahydrofurfuryl alcohol 97-99-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-13

97-99-4, Tetrahydrofurfuryl alcoholRelated Search:

Ethyl acetate Tetrahydrothiophene cis-1,2,3,6-Tetrahydrophthalic anhydride Tetrahydrofuran FURFURYL ALCOHOL RESIN Furfuryl alcohol Tetrahydrofurfuryl methacrylate Tetrahydrofurfuryl chloride 5,6,7,8-TETRAHYDRO-1-NAPHTHOL Tetrahydrofurfuryl bromide Tetrahydrofurfuryl acrylate TETRAHYDROTHIOPYRAN-4-CARBONITRILE Tetrahydrothiopyran-4-carbaldehyde 2H-Thiopyran-4-carboxylicacid,tetrahydro-(9CI) 1,1-Dioxo-tetrahydro-thiopyran-4-one Tetrahydrothiopyran-4-one Tetrahydrothiophen-3-one 3,4-Dithia-7H-cyclopenta[a]pentalene Tetrahydrofurfuryl alcohol

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