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BAY-885

Use In vitro
Product Name
BAY-885
CAS No.
2307249-33-6
Chemical Name
BAY-885
Synonyms
BAY-885;BAY-885 USP/EP/BP;BAY 885,ERK,inhibit,Extracellular signal regulated kinases,Inhibitor,BAY885,BAY-885;[2-amino-4-(trifluoromethoxy)phenyl]-{4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl}methanone;Methanone, [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-
CBNumber
CB64667614
Molecular Formula
C25H28F3N7O2
Formula Weight
515.53
MOL File
2307249-33-6.mol
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BAY-885 Property

Boiling point:
685.0±55.0 °C(Predicted)
Density 
1.362±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO:23.33(Max Conc. mg/mL);45.25(Max Conc. mM)
Ethanol:8.0(Max Conc. mg/mL);15.52(Max Conc. mM)
form 
A solid
pka
7.06±0.42(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb611265
Product name
BAY-885
Purity
>98%
Packaging
10mg
Price
$1208.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611265
Product name
BAY-885
Purity
>98%
Packaging
25mg
Price
$1802
Updated
2021/12/16
ChemScene
Product number
CS-0043294
Product name
BAY885
Purity
99.15%
Packaging
50mg
Price
$2600
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611265
Product name
BAY-885
Purity
>98%
Packaging
50mg
Price
$2691.1
Updated
2021/12/16
ChemScene
Product number
CS-0043294
Product name
BAY885
Purity
99.15%
Packaging
100mg
Price
$3600
Updated
2021/12/16
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BAY-885 Chemical Properties,Usage,Production

Use

BAY-885 is a highly potent and selective ERK5 inhibitor.

In vitro

BAY-885 shows potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and has no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM), thereby ruling out potential effects as a general inhibitor of transcription or translation.

BAY-885 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY-885 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6393
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52927
Advantage
58

2307249-33-6, BAY-885Related Search:


  • BAY-885
  • [2-amino-4-(trifluoromethoxy)phenyl]-{4-[7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl]piperidin-1-yl}methanone
  • Methanone, [2-amino-4-(trifluoromethoxy)phenyl][4-[7-(4-methyl-1-piperazinyl)pyrido[3,2-d]pyrimidin-4-yl]-1-piperidinyl]-
  • BAY-885 USP/EP/BP
  • BAY 885,ERK,inhibit,Extracellular signal regulated kinases,Inhibitor,BAY885,BAY-885
  • 2307249-33-6
  • C25H28F3N7O2