L-745,870 TRIHYDROCHLORIDE

Product Name: L-745,870 TRIHYDROCHLORIDE
CAS No.: 158985-00-3
Chemical Name: L-745,870 TRIHYDROCHLORIDE
Synonyms: 3HCl;L 745870;L 745870,L745870;L-745,870 trihydroch;L-745,870 TRIHYDROCHLORIDE;3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-;3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE
CBNumber: CB6481216
Molecular Formula: C18H19ClN4
Formula Weight: 326.82
MOL File: 158985-00-3.mol

More

Less

L-745,870 TRIHYDROCHLORIDE Property

Boiling point:: 571.4±50.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Desiccate at +4°C
solubility: DMSO:16.5(Max Conc. mg/mL);50.49(Max Conc. mM)
pka: 8.20±0.20(Predicted)
form: Solid
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 1002
Product name: L-745,870trihydrochloride
Purity: ≥99%(HPLC)
Packaging: 50
Price: $634
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 10MG
Price: $665.81
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 50MG
Price: $1073.29
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0003103
Product name: 3-((4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)METHYL)-1H-PYRROLO[2,3-B]PYRIDINE
Purity: 95.00%
Packaging: 1G
Price: $1529.85
Updated: 2021/12/16

ChemScene

Product number: CS-0003281
Product name: L-745870
Purity: 99.88%
Packaging: 5mg
Price: $82
Updated: 2021/12/16

More

Less

L-745,870 TRIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

L-745,870 is a drug which acts as a dopamine receptor antagonist selective for the D4 subtype, and has antipsychotic effects in animal models, though it was not effective in human trials.

Definition

ChEBI: 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine is a member of piperazines.

Biological Activity

A highly potent and selective D 4 dopamine receptor antagonist; L-745,870 has K i values of 0.51, 2300 and 960 nM for D 4 , D 3 and D 2 subtypes respectively and > 1000-fold selectivity over 5-HT 2 , D 1 and D 5 receptors.

L-745,870 TRIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

L-745,870 TRIHYDROCHLORIDE Suppliers

China 27 Germany 1 Japan 2 United Kingdom 3 United States 7 Global 40

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

International Laboratory Limited

Tel: --
Fax: --
Email: admin@intlab.org
Country: United States
ProdList: 5356
Advantage: 50

158985-00-3, L-745,870 TRIHYDROCHLORIDERelated Search:

hypochlorous acid 1-(2,9-diazabicyclo[4.3.0]nona-2,4,7,10-tetraen-7-yl)-N,N-dimethyl-methanamine 1-(4-Chlorophenyl)piperazine dihydrochloride 1H-Pyrrolo[2,3-b]pyridine, 3-(1-piperazinylmethyl)- 3-METHYL-7-AZAINDOLE 3-([4-(4-CHLOROPHENYL)PIPERAZIN-1-YL]METHYL)-1H-PYRROLO(2,3-B)PYRIDINE HYDROCHLORIDE 7-Azaindole L-745,870 TRIHYDROCHLORIDE

L-745,870 TRIHYDROCHLORIDE

3HCl

3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE

L 745870

3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine

1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-

L-745,870 trihydroch

L 745870,L745870

158985-00-3

C18H22Cl4N4

C18H19N4Cl3HCl