2-Methylthio-4-pyrimidinol
- Product Name
- 2-Methylthio-4-pyrimidinol
- CAS No.
- 5751-20-2
- Chemical Name
- 2-Methylthio-4-pyrimidinol
- Synonyms
- 2-(METHYLTHIO)PYRIMIDIN-4(3H)-ONE;2-(Methylthio)pyriMidin-4(1H)-one;NSC 125339;NSC 165518;AURORA 15138;2-Methyl Uracil;2-Methylthiouracil;2-Methylthio-4-pyrim;S-Methyl-2-thiouracil;2-Methylo-4-pyriMidinol
- CBNumber
- CB6690290
- Molecular Formula
- C5H6N2OS
- Formula Weight
- 142.18
- MOL File
- 5751-20-2.mol
2-Methylthio-4-pyrimidinol Property
- Melting point:
- 200.0 to 204.0 °C
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 7.80±0.40(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C5H6N2OS/c1-9-5-6-3-2-4(8)7-5/h2-3H,1H3,(H,6,7,8)
- InChIKey
- UYHSQVMHSFXUOA-UHFFFAOYSA-N
- SMILES
- C1(SC)=NC=CC(=O)N1
- CAS DataBase Reference
- 5751-20-2(CAS DataBase Reference)
- NIST Chemistry Reference
- 4(1H)-Pyrimidinone, 2-(methylthio)-(5751-20-2)
Safety
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S440043
- Product name
- 2-METHYLTHIO-4-PYRIMIDINOL
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $113
- Updated
- 2025/07/31
- Product number
- S440043
- Product name
- 2-METHYLTHIO-4-PYRIMIDINOL
- Purity
- Aldrich
- Packaging
- 250mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- S217336
- Product name
- 2-METHYLSULFANYL-PYRIMIDIN-4-OL
- Purity
- AldrichCPR
- Packaging
- 25MG
- Price
- $28.6
- Updated
- 2023/06/20
- Product number
- M2355
- Product name
- 2-Methylthio-4-pyrimidinol
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $18
- Updated
- 2025/07/31
- Product number
- M2355
- Product name
- 2-Methylthio-4-pyrimidinol
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $49
- Updated
- 2025/07/31
2-Methylthio-4-pyrimidinol Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A competitive inhibitor of Nitric Oxide Synthase (NOS).
Definition
ChEBI: 2-methylthiouracil is an aryl sulfide.
Synthesis
Sequentially, 800g of 2-thiouracil and 6L of water were added to a 10L reaction flask and stirred. Ice bath cooling, add sodium hydroxide 560g to the reaction bottle in batches, maintain the temperature below 40??. After the addition, the ice bath was cooled down to below 20 ??, and 944g of dimethyl sulfate was slowly added dropwise, and the temperature was controlled between 15-25 ?? during the dropwise process, and after the dropwise process, the reaction was kept warm for 4 h. The raw materials were basically reacted by HPLC. The reaction solution was adjusted to pH 1-2 with 6 mol/L dilute hydrochloric acid, and a white solid was precipitated. Decrease to about 20 ??, stirring 0.5h, filtration, filter cake with a large number of water to remove salt, pump dry, 50 ?? air drying. Obtained 805g of white solid powder, more than 98% of the liquid phase, yield 90.7%.
2-Methylthio-4-pyrimidinol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Methylthio-4-pyrimidinol manufacturers
- Product
- 2-Methylthio-4-pyrimidinol 5751-20-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-04-24
- Product
- 2-Methylthio-4-pyrimidinol 5751-20-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2025-04-09
- Product
- 2-Methylthio-4-pyrimidinol 5751-20-2
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2025-04-10