Trimethyl phosphonoacetate

ChemicalBook > CAS DataBase List > Trimethyl phosphonoacetate

Trimethyl phosphonoacetate

Product Name: Trimethyl phosphonoacetate
CAS No.: 5927-18-4
Chemical Name: Trimethyl phosphonoacetate
Synonyms: TMPA;METHYL DIMETHYLPHOSPHONOACETATE;Methyl (dimethoxyphosphoryl)acetate;NSC 84262;TRIMETHYL PHOPHONOACETATE;trimethylacetyl phosphate;TriMethyl phosphonoacetat;Trimethylphosphoroacetate;TRIMETHYL PHOSPHONACETATE;RIMETHYL PHOSPHONOACETATE
CBNumber: CB6726270
Molecular Formula: C5H11O5P
Formula Weight: 182.11
MOL File: 5927-18-4.mol

Less

Trimethyl phosphonoacetate Property

Melting point:: 242 °C
Boiling point:: 118 °C0.85 mm Hg(lit.)
Density: 1.125 g/mL at 25 °C(lit.)
refractive index: n20/D 1.437(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Liquid
Specific Gravity: approximate 1.265ｇ/ml (20℃)
color: Clear colorless to light yellow
Water Solubility: Slightly miscible with water.
BRN: 1865177
LogP: -0.680 (est)
CAS DataBase Reference: 5927-18-4(CAS DataBase Reference)
NIST Chemistry Reference: Trimethyl phosphonoacetate(5927-18-4)
EPA Substance Registry System: Acetic acid, (dimethoxyphosphinyl)-, methyl ester (5927-18-4)

Less

Safety

Safety Statements: 23-24/25
WGK Germany: 3
F: 9
TSCA: Yes
HS Code: 29310095

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T79758
Product name: Trimethyl phosphonoacetate
Purity: 98%
Packaging: 25g
Price: $102
Updated: 2024/03/01

Sigma-Aldrich

Product number: T79758
Product name: Trimethyl phosphonoacetate
Purity: 98%
Packaging: 100g
Price: $125
Updated: 2024/03/01

TCI Chemical

Product number: P1265
Product name: Trimethyl Phosphonoacetate
Purity: >96.0%(GC)
Packaging: 25g
Price: $52
Updated: 2024/03/01

TCI Chemical

Product number: P1265
Product name: Trimethyl Phosphonoacetate
Purity: >96.0%(GC)
Packaging: 250g
Price: $243
Updated: 2024/03/01

Alfa Aesar

Product number: A13301
Product name: Trimethyl phosphonoacetate, 98%
Packaging: 25g
Price: $42.65
Updated: 2024/03/01

Less

Trimethyl phosphonoacetate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

Trimethyl phosphonoacetate is used in the preparation of sarin A by intramolecular Mannich-type reactions. It is involved in the Horner-Wadsworth-Emmons olefination with aldehydes and ketones to give acrylic esters. It is also involved in oxa-Michael reactions, prenylation of oxindoles and heterocyclization reactions.

Application

Trimethyl phosphonoacetate is an important Wittig-horner reagent, which can be used to manufacture important intermediates of natural compounds such as vitamins, drugs, insect pheromones, etc.
Reactant involved in:
Intramolecular Mannich-type reactions to produce the sarain A diazatricyclic core
Organocatalytic oxa-Michael reactions
Prenylation and geranylation of oxindoles
Intramolecular Horner-Wadsworth-Emmons reactions
Olefin cross-metathesis / heterocyclization

Definition

ChEBI: Trimethyl phosphonoacetate is a phosphonic ester.

Trimethyl phosphonoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

3-METHOXYCARBONYL-3-SULFOLENE

Less

Trimethyl phosphonoacetate Suppliers

Americas 1 Belgium 3 CHINA 287 Europe 2 France 3 Germany 9 India 14 Italy 1 Japan 7 Slovakia 1 Switzerland 2 United Kingdom 13 United States 40 Global 383

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.

Tel: 133-96369453 18678026865
Fax: 0536-2101172
Email: sdfantai@163.com
Country: China
ProdList: 862
Advantage: 58

Weifang QianJin Fine Chemical Co., Ltd.

Tel: 13031698386 18753684562
Fax: 0536-8897109
Email: 1577399715@qq.COM
Country: China
ProdList: 1706
Advantage: 55

Nanjing Dilu Pharmaceutical Co., Ltd

Tel: 18014482516
Email: 977144864@qq.com
Country: China
ProdList: 402
Advantage: 58

IGM RESINS

Tel: 021-52080993 13917193189
Fax: 021-5208 0930，010-62620366，020-32008365
Email: selene.wu@igmresins.com
Country: China
ProdList: 89
Advantage: 57

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Beijing Donghualituo Techonlogy Development Co.,Ltd.

Tel: 010-88425576
Fax: (+86)-10-88425546
Email: sales@dhltchem.com
Country: China
ProdList: 793
Advantage: 59

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11655
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
Advantage: 52

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3295
Advantage: 57

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4552
Advantage: 62

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3203
Advantage: 55

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Suzhou Sibian Chemical Technology Co.,Ltd.

Tel: 0512-65617459 18915409046
Fax: 0512-65617459
Email: sales@sibian-chem.com
Country: China
ProdList: 1922
Advantage: 55

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Shanghai Zhuorui Chemical Co.,Ltd.

Tel: 021-69180038
Fax: 0086-21-39177059
Email: zhuoruichem@163.com
Country: China
ProdList: 105
Advantage: 58

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Beijing Universal Century Technology Co., Ltd.

Tel: 400-8706899
Fax: 400-8706899
Email: hysj_bj.com
Country: China
ProdList: 3583
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9978
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Shanghai DiBai Chemicals Co., Ltd.

Tel: 021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3991
Advantage: 60

Less

View Lastest Price from Trimethyl phosphonoacetate manufacturers

hebei hongtan Biotechnology Co., Ltd

Product: Trimethyl phosphonoacetate 5927-18-4
Price: US $30.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-03-25

Hebei Yanxi Chemical Co., Ltd.

Product: Trimethyl phosphonoacetate 5927-18-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-29

Hebei Weibang Biotechnology Co., Ltd

Product: Trimethyl phosphonoacetate 5927-18-4
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

5927-18-4, Trimethyl phosphonoacetateRelated Search:

Methylparaben Vinyl acetate Methyl acetate Amyl acetate POLY(VINYL ACETATE) Trimethyl borate Sodium acetate Tocopheryl acetate Triacetin Ethyl 2-(Chlorosulfonyl)acetate Glatiramer acetate Ethyl acetate Ammonium acetate Bensulfuron methyl Cellulose acetate Linalyl acetate Methyl acrylate Kresoxim-methyl

TriMethyl phosphonoacetate, 98% 25GR

Dimethylphosphonoacetic Acid Methyl Ester Methyl Dimethylphosphonoacetate Phosphonoacetic Acid Trimethyl Ester

TriMethyl phosphonoacetat

Aceticacid, 2-(diMethoxyphosphinyl)-, Methyl ester

Dibenzyloxyphosphoiyl three Methyl acetate

(Carboxymethyl)phosphonic acid trimethyl ester

Dimethyl methoxycarbonylmethylphosphonate~Phosphonoacetic acid trimethyl ester

TMPA

trimethylacetyl phosphate

TRIMETHYL PHOPHONOACETATE

Dimethyl (methoxycarbonyl)methylphosphonate, 98 %

(Dimethoxyphosphinyl)acetic acid methyl

2-(Dimethoxyphosphinyl)acetic acid methyl

Dimethoxyphosphinylacetic acid methyl

Methoxycarbonylmethylphosphonic acid dimethyl ester

(Dimethoxy-phosphoryl)-aceticacidmethylester

Trimethylphosphonoacetate,98%

TriMethyl phosphonoacetate, 98% 100GR

Trimethylphosphonoyl acetate

NSC 84262

Dimethyl methoxycarbonylmethanephosphonate for synthesis

(dimethoxyphosphinyl)-aceticacimethylester

Trimethylphosphoroacetate

METHYL DIMETHYLPHOSPHONOACETATE

Methyl (dimethoxyphosphoryl)acetate

(DIMETHOXYPHOSPHINYL)ACETIC ACID METHYL ESTER

DIMETHYL METHOXYCARBONYLMETHANEPHOSPHONATE

DIMETHYL (METHOXYCARBONYL)METHYLPHOSPHONATE

DIMETHYLPHOSPHONOACETIC ACID METHYL ESTER

ACETIC ACID, (DIMETHOXYPHOSPHINYL)-, METHYL ESTER

PHOSPHONOACETIC ACID TRIMETHYL ESTER

TRIMETHYL PHOSPHONACETATE

TRIMETHYL PHOSPHONOACETATE

TrimethylPhosphonoacetate&gt

Trimethyl phosphonoacetate, 98%, for synthesis

Trimethyl phosphonylacetate

RIMETHYL PHOSPHONOACETATE

Phosphonyl acetate trimethyl ester

5927-18-4

CH3O2POCH2CO2CH3

C5H11O5P

Horner-Wadsworth-Emmons Reagents

Olefination

Synthetic Reagents

Wittig & Horner-Emmons Reaction

Horner-Emmons Reaction

C-C Bond Formation

Horner-Emmons Reaction

Synthetic Organic Chemistry

Wittig & Horner-Emmons Reaction

C-C Bond Formation

Horner-Wadsworth-Emmons Reagents

Olefination

5927-18-4