CLOTHIAPINE Property

Melting point:

121-123℃

Boiling point:

163.4°C (rough estimate)

Density 

1.2405 (rough estimate)

refractive index 

1.6000 (estimate)

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Off-white solid (m.p. 118-120°C).

pka

7.22±0.42(Predicted)

color 

White to light yellow

Stability:

Hygroscopic

Safety

Toxicity

LD50 oral in rat: 280mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

CLOTHIAPINE Chemical Properties,Usage,Production

Uses

Antipsychotic.

Definition

ChEBI: Clotiapine is a dibenzothiazepine.

Safety Profile

Poison by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and SOx.