ChemicalBook > CAS DataBase List > 3-Hydroxypyridine

3-Hydroxypyridine

Product Name
3-Hydroxypyridine
CAS No.
109-00-2
Chemical Name
3-Hydroxypyridine
Synonyms
3-PYRIDINOL;PYRIDIN-3-OL;3-PYRIDONE;2(1H)-PYRIDONE;3-HP;NSC 18470;2-PYRIDON;3-PYRIDOL;B-PYRIDONE;β-Pyridinone
CBNumber
CB6852775
Molecular Formula
C5H5NO
Formula Weight
95.1
MOL File
109-00-2.mol
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3-Hydroxypyridine Property

Melting point:
125-128 °C (lit.)
Boiling point:
280-281 °C(lit.)
Density 
1.1418 (rough estimate)
refractive index 
1.5939 (estimate)
Flash point:
173°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
33g/l
form 
Crystalline Powder
pka
4.79, 8.75(at 20℃)
color 
Beige to brown
PH
6.0-6.5 (33g/l, H2O, 20℃)
Water Solubility 
32.26g/L(20 ºC)
BRN 
105699
LogP
0.480
CAS DataBase Reference
109-00-2(CAS DataBase Reference)
NIST Chemistry Reference
3-Pyridinol(109-00-2)
EPA Substance Registry System
3-Pyridinol (109-00-2)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-36-37/39-22
WGK Germany 
3
RTECS 
UV1144050
F 
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H57009
Product name
3-Hydroxypyridine
Purity
98%
Packaging
25g
Price
$38.5
Updated
2024/03/01
Sigma-Aldrich
Product number
H57009
Product name
3-Hydroxypyridine
Purity
98%
Packaging
100g
Price
$46.3
Updated
2024/03/01
TCI Chemical
Product number
H0331
Product name
3-Hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$46
Updated
2024/03/01
TCI Chemical
Product number
H0331
Product name
3-Hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$115
Updated
2024/03/01
Alfa Aesar
Product number
A13910
Product name
3-Hydroxypyridine, 98%
Packaging
50g
Price
$26.65
Updated
2024/03/01
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3-Hydroxypyridine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal. Soluble in alcohol and water, slightly soluble in ether and benzene. It becomes a red solution when it encounters ferric chloride, and it is easy to decompose in the air.

Uses

3-Hydroxypyridine (cas# 109-00-2) is a compound useful in organic synthesis.

Preparation

3-hydroxypyridine was prepared by reacting furfurylamine with H2O2 in the presence of HCl, followed by hydrolysis. The optimal conditions were found as fellows: molar ratio of furfurylamine: HCl : H2O2 = 1 : 5 : 1.1, and H2O2 added dropwisely at 0-5 °C, and then refluxed at 100-105 °C for 0.5 h.

Definition

ChEBI: 3-Hydroxypyridine is a monohydroxypyridine that is pyridine in which the hydrogen at position 3 has been replaced by a hydroxy group. It has been detected as a thermal degradation product from the smoke of the burning leaves of Salvia divinorum, a Mexican psychoactive plant.

brand name

Ventavis (Schering).

Purification Methods

Crystallise 3-hydroxypyridine from *C6H6, water or EtOH. [Beilstein 21 III/IV 402, 21/2 V 68.]

3-Hydroxypyridine Preparation Products And Raw materials

Raw materials

FUMING SULFURIC ACID 3-Pyridinesulfonic acid MERCURY(II) SULFATE

Preparation Products

3-Pyridyl dimethylcarbamate 3-METHOXY-PYRIDINE-2-CARBALDEHYDE 5-methoxypyridin-3-amine
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View Lastest Price from 3-Hydroxypyridine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
3-Hydroxypyridine 109-00-2
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-19
Hebei Zhuanglai Chemical Trading Co Ltd
Product
3-Pyridinol 109-00-2
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
3-Hydroxypyridine 109-00-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-25

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