Description
ChemicalBook > CAS DataBase List > EC 3.1.31.1

EC 3.1.31.1

Description
Product Name
EC 3.1.31.1
CAS No.
9013-53-0
Chemical Name
EC 3.1.31.1
Synonyms
MNase;NUCLEASE;EC 3.1.31.1;NUCLEASE S7;IUB: 3.1.31.1;Micrococcal Nuteus;MICROCOCCAL NUCLEASE;Micrococcus nuclease;NUCLEASE, MICROCOCCAL;NUCLEASE, MICROCOCCUS
CBNumber
CB7107335
Formula Weight
0
MOL File
Mol file
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EC 3.1.31.1 Property

storage temp. 
-20°C
solubility 
aqueous buffer: 1mg/mL
form 
Lyophilized off-white solid
color 
White to off-white
biological source
Staphylococcus aureus
Specific Activity
100-300units/mg protein
Major Application
diagnostic assay manufacturing
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10-21
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N5386
Product name
Nuclease micrococcal from Staphylococcus aureus
Purity
100-300?units/mg protein
Packaging
50units
Price
$205
Updated
2026/03/19
Sigma-Aldrich
Product number
N5386
Product name
Nuclease micrococcal from Staphylococcus aureus
Purity
100-300?units/mg protein
Packaging
200units
Price
$515
Updated
2026/03/19
Sigma-Aldrich
Product number
N5386
Product name
Nuclease micrococcal from Staphylococcus aureus
Purity
100-300?units/mg protein
Packaging
500units
Price
$1020
Updated
2026/03/19
Sigma-Aldrich
Product number
N3755
Product name
Nuclease micrococcal from Staphylococcus aureus
Purity
100-300?units/mg protein
Packaging
50units
Price
$177
Updated
2026/03/19
Sigma-Aldrich
Product number
N3755
Product name
Nuclease micrococcal from Staphylococcus aureus
Purity
100-300?units/mg protein
Packaging
200units
Price
$485
Updated
2026/03/19
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EC 3.1.31.1 Chemical Properties,Usage,Production

Uses

Nuclease S7 has been used in ribonuclease selection process for ribosome profiling.

Uses

Nuclease from Staphylococcus aureus has been used in a study to assess coagulase and heat-resistant strains found in animals. It has also been used in a study to investigate the expression characteristic of two genes in S. aureus that encode two thermostable nucleases.

Uses

Micrococcal Nuclease can be used for the digestion of chromatin to identify the location of nucleosomes.

Biochem/physiol Actions

Cleavage of DNA by Nuclease micrococcal is greater at the 5′ sides of A or T nucleotides than at G or C.

Description

Micrococcal nuclease is a relatively non-specific endo-exonuclease derived from Staphylococcus aureus. Active in the pH range of 7.0-10.0, this product digests double-stranded, single-stranded, circular, and linear nucleic acids.In the SimpleChIP® Enzymatic Chromatin IP kit assay, following cell lysis, the chromatin is fragmented by partial digestion with micrococcal nuclease to obtain chromatin fragments of 1 to 5 nucleosomes in size. Enzymatic digestion of chromatin is much milder than sonication and eliminates problems due to variability in sonication power and emulsification of chromatin during sonication, which can result in incomplete fragmentation of chromatin or loss of antibody epitopes due to protein denaturation and degradation.This product is offered to conveniently provide additional micrococcal nuclease when fragmenting chromatin with our SimpleChIP® and SimpleChIP® Plus Enzymatic Chromatin IP Kits. These kits provide all the reagents required for performing 6 chromatin preparations (or optimizations) and 30 chromatin immunoprecipitation (ChIP) assays, however there are instances where extra micrococcal nuclease is desired.

EC 3.1.31.1 Preparation Products And Raw materials

Raw materials

Preparation Products

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EC 3.1.31.1 Suppliers

Shanghai Baoman Biotechnology Co., Ltd.
Tel
021-62130998
Fax
021-54438215
Email
baomanbio@163.com
Country
China
ProdList
174
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
26695
Advantage
65
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-84699383-8003;025-846993838003-8003 18013301593;18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3293
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15781
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Shanghai Zhen Li Biological Technology Co., Ltd
Tel
021-16621358918; 18516310516
Fax
13045646768
Email
zhenlipharma888@163.com
Country
China
ProdList
19065
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-62971590 18548936886
Fax
010-62340519
Email
3462612863@qq.com
Country
China
ProdList
10063
Advantage
58
Guangzhou Tomums Life Science Co., Ltd.
Tel
020-31155029 18902330969
Fax
020-31155029
Email
sales@tomums.cn
Country
China
ProdList
4696
Advantage
58
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View Lastest Price from EC 3.1.31.1 manufacturers

Career Henan Chemical Co
Product
EC 3.1.31.1 9013-53-0
Price
US $1.00/g
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-09

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