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Esomeprazole potassium

Product Name
Esomeprazole potassium
CAS No.
161796-84-5
Chemical Name
Esomeprazole potassium
Synonyms
Esomeprazole potassium;(S)-Omeprazole potassium;Esomeprazole potassium USP/EP/BP;Esomeprazole Impurity 46 Potassium Salt;(S)-5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d];potassium,5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide;(R)-5-METHOXY-2-((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYLSULFINYL)BENZO[D]IMIDAZOL-1-IDE POTASSIUM SALT;6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole potassium salt (1:1);1H-Benzimidazole,6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-,potassium salt (1:1)
CBNumber
CB71229920
Molecular Formula
C17H20KN3O3S
Formula Weight
385.52
MOL File
161796-84-5.mol
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Esomeprazole potassium Property

vapor pressure 
0Pa at 25℃
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0002606
Product name
ESOMEPRAZOLE POTASSIUM
Purity
95.00%
Packaging
25MG
Price
$626.15
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002606
Product name
ESOMEPRAZOLE POTASSIUM
Purity
95.00%
Packaging
100MG
Price
$771.79
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002606
Product name
ESOMEPRAZOLE POTASSIUM
Purity
95.00%
Packaging
500MG
Price
$1466.09
Updated
2021/12/16
DC Chemicals
Product number
DC24176
Product name
Esomeprazolepotassiumsalt
Purity
>98%
Packaging
1g
Price
$800
Updated
2021/12/16
Crysdot
Product number
CD31003158
Product name
Esomeprazolepotassium
Purity
98+%
Packaging
50mg
Price
$126
Updated
2021/12/16
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Esomeprazole potassium Chemical Properties,Usage,Production

Uses

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole potassium salt has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].

in vivo

Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis[2].

Animal Model:C57BL/6J mice (8-weeks old, 25-30 g) treated with cotton smoke-induced lung injury[2]
Dosage:30 mg/kg, 300 mg/kg
Administration:Oral gavage; daily; for 19 or 11 days
Result:Significantly inhibited the progression of fibrosis throughout the lungs of the animals.

References

[1] Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46. DOI:10.18433/j34608
[2] Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16. DOI:10.3389/fphar.2017.00016
[3] Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9. DOI:10.1093/ajhp/59.14.1333

Esomeprazole potassium Preparation Products And Raw materials

Raw materials

Preparation Products

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Esomeprazole potassium Suppliers

Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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China
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MedChemexpress LLC
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021-58955995
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609-228-5909
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United States
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ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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China
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Hubei widely chemical technology Co., Ltd.
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027-83991130 18627774460
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027-83991130
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1718093273@QQ.COM
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China
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Amadis Chemical Company Limited
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571-89925085
Fax
0086-571-89925065
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sales@amadischem.com
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China
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Hubei widely chemical technology Co., Ltd.
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027-59402396 13419635609
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13419635609@163.com
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China
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Wellman Pharmaceutical Group Limited
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Musechem
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
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+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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Fan De(Beijing) Biotechnology Co., Ltd.
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15911056312
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liming@bio-fount.com
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China
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View Lastest Price from Esomeprazole potassium manufacturers

Career Henan Chemica Co
Product
Esomeprazole potassium 161796-84-5
Price
US $1.00/g
Min. Order
1g
Purity
85.0-99.8%
Supply Ability
20ton
Release date
2020-10-29
Dideu Industries Group Limited
Product
Esomeprazole potassium 161796-84-5
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-17

161796-84-5, Esomeprazole potassiumRelated Search:


  • (S)-Omeprazole potassium
  • 6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole potassium salt (1:1)
  • (R)-5-METHOXY-2-((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYLSULFINYL)BENZO[D]IMIDAZOL-1-IDE POTASSIUM SALT
  • Esomeprazole potassium
  • (S)-5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]
  • potassium,5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
  • 1H-Benzimidazole,6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-,potassium salt (1:1)
  • Esomeprazole potassium USP/EP/BP
  • Esomeprazole Impurity 46 Potassium Salt
  • 161796-84-5