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MONOETHYLGLYCINEXYLIDIDE

Product Name
MONOETHYLGLYCINEXYLIDIDE
CAS No.
7728-40-7
Chemical Name
MONOETHYLGLYCINEXYLIDIDE
Synonyms
MEGX;N-(2,6-DIMETHYLPHENYL)-2-(ETHYLAMINO)ACETAMIDE;L-86;MGEX;Norlidocaine;Lidocaine-006;Ethylglycylxylidide;Lidocaine Impurity 9;N-Ethylglycinexylidide;Monoethylglycylxylidide
CBNumber
CB7134762
Molecular Formula
C12H18N2O
Formula Weight
206.28
MOL File
7728-40-7.mol
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MONOETHYLGLYCINEXYLIDIDE Property

Melting point:
242-245°C
Boiling point:
335.6±30.0℃ (760 Torr)
Density 
1.047±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
127.8±24.7℃
storage temp. 
2-8°C
solubility 
H2O: soluble10mg/mL, clear
pka
pKa 8.04(H2O,t =25±0.2,I=0.01(NaCl)) (Uncertain)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
AN7740000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0087
Product name
MEGX
Purity
≥95% (HPLC)
Packaging
5mg
Price
$131
Updated
2024/03/01
Sigma-Aldrich
Product number
16866
Product name
Monoethylglycinexylidine
Purity
analytical standard
Packaging
25mg
Price
$207
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0087
Product name
MEGX
Purity
≥95% (HPLC)
Packaging
25mg
Price
$527
Updated
2024/03/01
TRC
Product number
KIT8700
Product name
NorLidocaine(1.0mg/mLinMethanol)
Packaging
1x1ml
Price
$160
Updated
2021/12/16
Usbiological
Product number
018542
Product name
Nor Lidocaine
Packaging
2.5mg
Price
$425
Updated
2021/12/16
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MONOETHYLGLYCINEXYLIDIDE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine.

Uses

A metabolite of Lidocaine (L397800).

Definition

ChEBI: Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.

Biochem/physiol Actions

Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine.

MONOETHYLGLYCINEXYLIDIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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7728-40-7, MONOETHYLGLYCINEXYLIDIDERelated Search:


  • MONOETHYLGLYCINEXYLIDIDE
  • N-(2,6-DIMETHYLPHENYL)-2-(ETHYLAMINO)ACETAMIDE
  • Monoethyl Glycinexylidide-d6 HCl
  • L-86
  • MEGX
  • N-Ethylglycinexylidide
  • Norlidocaine
  • N1-(2,6-DiMethylphenyl)-2-(ethylaMino)acetaMide
  • 2-(EthylaMino)-2',6'-acetoxylidide
  • Monoethylglycylxylidide
  • N-(N-Ethylglycyl)-2,6-xylidine
  • ω-EthylaMino-2',6'-diMethyl- acetanilide
  • Monoethylglycinexylidide HCl
  • Monoethylglycinexylidide HCl (IMpurity D)
  • Lidocaine impurity 5/Lidocaine EP Impurity D/Nor Lidocaine/N-Desethyl Lidocaine/N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide
  • Lidocaine Impurity 9
  • Lidocaine-006
  • Monoethylglycinexylidine HCl (IMpurity D)
  • MGEX
  • Monoethylglycinexylidine
  • Ethylglycylxylidide
  • Acetamide, N-(2,6-dimethylphenyl)-2-(ethylamino)-
  • Nor Lidocaine (1.0 mg/mL in Methanol)
  • 7728-40-7
  • C12H12N2OD6HCl
  • Amines, Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals