dihydrolycorine

ChemicalBook > CAS DataBase List > dihydrolycorine

Uses

Product Name: dihydrolycorine
CAS No.: 6271-21-2
Chemical Name: dihydrolycorine
Synonyms: Dihydrolycorine,inhibit,Inhibitor;(1S,2S,3aR,12bS,12cR)-2,3,3a,4,5,7,12b,12c-Octahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol;1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,3,3a,4,5,7,12b,12c-octahydro-, (1S,2S,3aR,12bS,12cR)-
CBNumber: CB71381082
Molecular Formula: C16H19NO4
Formula Weight: 289.33
MOL File: 6271-21-2.mol

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dihydrolycorine Property

Melting point:: 247 °C
Boiling point:: 460.5±45.0 °C(Predicted)
Density: 1.48
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Cryst.
pka: 14.13±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27809
Product name: Dihydrolycorine
Packaging: 1mg
Price: $67
Updated: 2024/03/01

Cayman Chemical

Product number: 27809
Product name: Dihydrolycorine
Packaging: 25mg
Price: $1065
Updated: 2024/03/01

Cayman Chemical

Product number: 27809
Product name: Dihydrolycorine
Packaging: 5mg
Price: $297
Updated: 2024/03/01

Cayman Chemical

Product number: 27809
Product name: Dihydrolycorine
Packaging: 10mg
Price: $493
Updated: 2024/03/01

TRC

Product number: D451808
Product name: Dihydrolycorine
Packaging: 1mg
Price: $60
Updated: 2021/12/16

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dihydrolycorine Chemical Properties,Usage,Production

Uses

Dihydrolycorine is a derivative of Lycorine, the main phenanthridine Amaryllidaceae alkaloid which exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli.

Description

Dihydrolycorine is a derivative of the alkaloid lycorine that has antihypertensive and neuroprotective activities. It inhibits methoxamine-induced contraction of isolated rabbit aortic rings and rat anococcygeus muscle with pA₂ values of 5.93 and 6.35, respectively. Dihydrolycorine reduces mean arterial pressure (MAP) in anesthetized and conscious normotensive rats when administered at a dose of 80 mg/kg. It also reduces electrically or phenylephrine-induced hypertension in pithed rats. Dihydrolycorine reduces infarct size, cerebral edema, and myeloperoxidase activity in a rat model of focal cerebral ischemia-reperfusion injury when administered following reperfusion.

Uses

Dihydrolycorine is a derivative of Lycorine (L487550), the main phenanthridine Amaryllidaceae alkaloid which exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli.

target

Adrenergic Receptor

dihydrolycorine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from dihydrolycorine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: dihydrolycorine 6271-21-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: dihydrolycorine 6271-21-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: Dihydrolycorine 6271-21-2
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

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(1S,2S,3aR,12bS,12cR)-2,3,3a,4,5,7,12b,12c-Octahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol

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Dihydrolycorine,inhibit,Inhibitor

6271-21-2