4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene

Product Name: 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
CAS No.: 461432-23-5
Chemical Name: 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Synonyms: 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene;Dapagliflozin Bromo impurity;Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]-;Dapagliflozin-13;Dapaglifozin DAP Bromo;5-broMo-2-chloro-4’Dapagliflozin Impurity 15;4-(Dibenzofuranyl)boronic;Dapagliflozin Impurity 82;Dapagliflozin Intermediate 1
CBNumber: CB71456759
Molecular Formula: C15H14BrClO
Formula Weight: 325.63
MOL File: 461432-23-5.mol

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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Property

Boiling point:: 393.0±32.0 °C(Predicted)
Density: 1.371±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Low-Melting Solid
color: White to Off-White
Stability:: Stable under recommended storage conditions., Stable Under Recommended Storage C
InChI: InChI=1S/C15H14BrClO/c1-2-18-14-6-3-11(4-7-14)9-12-10-13(16)5-8-15(12)17/h3-8,10H,2,9H2,1H3
InChIKey: ZUNCHZBITMUSRD-UHFFFAOYSA-N
SMILES: C1(Cl)=CC=C(Br)C=C1CC1=CC=C(OCC)C=C1

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Safety

HS Code: 2909309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B682175
Product name: 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Packaging: 1g
Price: $460
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB76075
Product name: 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Packaging: 50g
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-B0023
Product name: 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Purity: 98.57%
Packaging: 100g
Price: $158
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB76075
Product name: 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene
Packaging: 10g
Price: $180
Updated: 2021/12/16

Matrix Scientific

Product number: 083813
Product name: 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether
Purity: 97%
Packaging: 5g
Price: $242
Updated: 2021/12/16

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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Chemical Properties,Usage,Production

Uses

5-Bromo-2-chloro-4'-ethoxydiphenylmethane is a hydrocarbon derivative and can be used as an intermediate for dapagliflozin.

Synthesis

Oxalyl chloride (0.8 mL) was added to a solution of 5-bromo-2-chlorobenzoic acid (2 g) in dichloromethane (20 mL) and dimethylformamide (0.2 mL) under a nitrogen atmosphere. The reaction mixture was stirred for one hour at 25° C to 30° C. After completion of the reaction, the reaction mixture was concentrated under a vacuum at 40° C to 45° C. to obtain an oily residue. The oily residue was dissolved in dichloromethane (20 mL) and cooled to 0° C. To this solution, phenol (1.1 mL) and aluminium chloride (2.3 g) were added at 0° C. to 5° C. The reaction mixture was stirred at 0° C to 5° C for 2 hours. The reaction mixture was allowed to warm to about 20° C, and triethylsilane (3.4 mL) was slowly added to it at the same temperature. The reaction mixture was stirred for about 36 hours from 20° C to 25° C. After completion of the reaction, 4-bromo-1-chloro-2-(4-ethoxybenzyl)benzene was obtained by further purification.

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Suppliers

China 484 India 53 United Kingdom 5 United States 15 Global 557

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View Lastest Price from 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene manufacturers

Nanjing Fred Technology Co., Ltd

Product: 5-bromo-2-chloro-4'-ethoxydiphenylmethane 461432-23-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2024-01-03

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 5-bromo-2-chloro-4’-ethoxydiphenylmethane 461432-23-5
Price: US $999.00-666.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-20

hebei hongtan Biotechnology Co., Ltd

Product: 5-bromo-2-chloro-4’-ethoxydiphenylmethane 461432-23-5
Price: US $80.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 500
Release date: 2024-03-20

461432-23-5, 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzeneRelated Search:

2-(5-BroMo-2-Methylbenzyl)-5-(4-fluorophenyl)thiophene (R)-3-(4-(5-broMo-2-chlorobenzyl)phenoxy)tetrahydrofuran 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone 4-(5-broMo-2-chlorobenzyl)phenol 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Empagliflozin Canagliflozin heMihydrate PF-04971729 Ipragliflozin Canagliflozin 2,3,4,6-TETRA-O-PIVALOYL-ALPHA-D-GLUCOPYRANOSYL BROMIDE Donepezil 1-Chloro-2-(4-ethoxybenzyl)-4-iodobenzene 5-Bromo-2-chlorobenzoic acid (5-broMo-2-chlorophenyl)(2-ethoxyphenyl)Methanone (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone 4-BROMO-1-CHLORO-2-ETHYLBENZENE 5-bromo-2-chloro-4’-ethoxydiphenylmethane

5-bromo-2-chloro-4’-ethoxydiphenylmethane

Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]-

4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether

Dapagliflozin Intermediate 1

4-broMo-1-chloro-2-[(4-ethoxyphenyl)Methyl]-

2-(4-Methoxybenzyl)-4-broMo-1-chlorobenzene

1-(5-broMo-2-chlorobenzyl)-4-ethoxybenzene

Dapagliflozin-13

Dapagliflozin Bromo impurity

4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene

5-broMo-2-chloro-4&rsquo

Dapagliflozin Intermediate II

Dapagliflozin Intermediate 2

5-bromo-2-chloro-4'-ethoxydiphenylmethane###461432-23-5

(5-bromo-2-chlorobenzyl)-4-ethoxybenzene

4-(5-Brom-2-chlorbenzyl)phenyl-ethylether

Dapagliflozin Impurity 15

4-(Dibenzofuranyl)boronic

4-(5-Bromo-2-chlorobenzy)phenylethyl ester

Dapagliflozin Impurity 82

4-Bromo-1-chloro-2-(4-ethoxybenzyl)

Dapagliflozin Despyranose Bromo Impurity

4-Brom-1-chlor-2-(4-ethoxybenzyl)benzol

5-bromo-2-chloro-4’-ethoxydiphenylmethane ISO 9001：2015 REACH

4-(3-((1-ethoxyethoxy)methyl)-4-bromophenoxy)benzonitrile

Supply 5-bromo-2-chloro-4'-ethoxydiphenylmethane

Dapaglifozin DAP Bromo

5-bromo-2-chloro-4-ethoxydiphenylmethaneQ: What is 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the CAS Number of 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the storage condition of 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What are the applications of 5-bromo-2-chloro-4-ethoxydiphenylmethane

Dapagliflozin Intermediate/ 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane

4-(5- bromo -2- chlorobenzyl) phenethyl ether

5-Bromo-2-chIoro-4’-ethoxydiphenyImethane

4-Bromo-1-ChIoro 2-4-EthoxybenzyI-Benzene

4-bromo-l-chloro-2-(4-ethoxybenzyl)benzene

2-(4-ethoxybenzyl)-4-bromo-1-chloro benzene

5-bromo-2-chloro-4’-ethoxydiphenylmethane, Or 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether

(5-Bromo-2-chlorobenzyl)phenyl ethyl ether

5-bromo-2-chloro-4'-ethoxydiphenylmethane

6-bromo-2-chloro-4’-ethoxydiphenylmethane

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene

461432-23-5

61432-23-5

100134-06-9

9461432-23-5

C15H14BrClO

Halides

Phenyls & Phenyl-Het

461432-23-5

ADVANCED INT.