3-CHLOROISONICOTINALDEHYDE
- Product Name
- 3-CHLOROISONICOTINALDEHYDE
- CAS No.
- 72990-37-5
- Chemical Name
- 3-CHLOROISONICOTINALDEHYDE
- Synonyms
- 3-CHLORO-4-FORMYLPYRIDINE;3-CHLOROISONICOTINALDEHYDE;3-Chloronocotincarboxaldehyde;3-Chloro-4-pyridinecarbaldehyde;3-CHLORO-4-PYRIDINECARBOXALDEHYDE;3-CHLOROPYRIDINE-4-CARBOXALDEHYDE;4-Pyridinecarboxaldehyde, 3-chloro-;3-Chloro-4-pyridinecarboxaldehyde >3-Chloro-4-pyridinecarboxaldehyde 97%;3-chloro-2-forMylpyridine-4-carboxylic acid
- CBNumber
- CB7156742
- Molecular Formula
- C6H4ClNO
- Formula Weight
- 141.56
- MOL File
- 72990-37-5.mol
3-CHLOROISONICOTINALDEHYDE Property
- Melting point:
- 58-62 °C(lit.)
- Boiling point:
- 93°C/6mmHg(lit.)
- Density
- 1.332±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Methanol
- pka
- 0.97±0.18(Predicted)
- form
- Crystalline Powder
- color
- White to yellow
- Sensitive
- Air Sensitive
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/38-43-36/37/38
- Safety Statements
- 37/39-36-26
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
N-Bromosuccinimide Price
- Product number
- C2542
- Product name
- 3-Chloro-4-pyridinecarboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $32
- Updated
- 2025/07/31
- Product number
- C2542
- Product name
- 3-Chloro-4-pyridinecarboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $125
- Updated
- 2025/07/31
- Product number
- C367388
- Product name
- 3-Chloroisonicotinaldehyde
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FC32271
- Product name
- 3-Chloro-4-pyridinecarbaldehyde
- Packaging
- 2g
- Price
- $63
- Updated
- 2021/12/16
- Product number
- B373
- Product name
- 3-Chloro-4-pyridinecarboxaldehyde
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
3-CHLOROISONICOTINALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
off-white to light yellow solid
Synthesis
626-60-8
68-12-2
72990-37-5
The general procedure for the synthesis of 3-chloropyridine-4-carbaldehyde from 3-chloropyridine and N,N-dimethylformamide is as follows: 1. add toluene to a 250 mL round-bottomed flask and cool to -78°C. 2. LDA (11 mL, 22.02 mmol) was slowly added dropwise to a solution of 3-chloropyridine (8.80 mmol) in THF (20 mL) at -78°C and stirred at the same temperature for 1 to 2 hours. 3. DMF (822 μL, 10.56 mmol) was added, then the reaction mixture was brought to room temperature and stirred for 1 hour. 4. Ethyl acetate (EA) and water were added to the reaction mixture and the organic and aqueous layers were separated. 5. The organic solvent was further extracted with the aqueous phase and the organic extracts were combined. 6. The combined organic extracts were dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated in vacuum. 7. The crude product was purified by silica gel column chromatography to afford 3-chloropyridine-4-carbaldehyde (0.33 g, 30-65% yield). 8. The structure of the product was determined by NMR. 8. The structure of the product was confirmed by NMR (400 MHz, CDCl3): δ 7.73 (d, J = 8.0 Hz, 1H), 8.71 (d, J = 4.0 Hz, 1H), 8.81 (s, 1H), 10.52 (s, 1H).
References
[1] Heterocycles, 2006, vol. 67, # 2, p. 543 - 547
[2] Patent: WO2015/88271, 2015, A1. Location in patent: Page/Page column 208
3-CHLOROISONICOTINALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
3-CHLOROISONICOTINALDEHYDE Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 3-CHLOROISONICOTINALDEHYDE manufacturers
- Product
- 3-CHLOROISONICOTINALDEHYDE 72990-37-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-14
- Product
- 3-CHLOROISONICOTINALDEHYDE 72990-37-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-02
- Product
- 3-CHLOROISONICOTINALDEHYDE 72990-37-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2018-12-14