ChemicalBook > CAS DataBase List > 3-CHLOROISONICOTINALDEHYDE

3-CHLOROISONICOTINALDEHYDE

Product Name
3-CHLOROISONICOTINALDEHYDE
CAS No.
72990-37-5
Chemical Name
3-CHLOROISONICOTINALDEHYDE
Synonyms
3-CHLORO-4-FORMYLPYRIDINE;3-CHLOROISONICOTINALDEHYDE;3-Chloronocotincarboxaldehyde;3-Chloro-4-pyridinecarbaldehyde;3-CHLORO-4-PYRIDINECARBOXALDEHYDE;3-CHLOROPYRIDINE-4-CARBOXALDEHYDE;4-Pyridinecarboxaldehyde, 3-chloro-;3-Chloro-4-pyridinecarboxaldehyde >3-Chloro-4-pyridinecarboxaldehyde 97%;3-chloro-2-forMylpyridine-4-carboxylic acid
CBNumber
CB7156742
Molecular Formula
C6H4ClNO
Formula Weight
141.56
MOL File
72990-37-5.mol
More
Less

3-CHLOROISONICOTINALDEHYDE Property

Melting point:
58-62 °C(lit.)
Boiling point:
93°C/6mmHg(lit.)
Density 
1.332±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
soluble in Methanol
pka
0.97±0.18(Predicted)
form 
Crystalline Powder
color 
White to yellow
Sensitive 
Air Sensitive
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/38-43-36/37/38
Safety Statements 
37/39-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C2542
Product name
3-Chloro-4-pyridinecarboxaldehyde
Purity
>98.0%(GC)
Packaging
1g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
C2542
Product name
3-Chloro-4-pyridinecarboxaldehyde
Purity
>98.0%(GC)
Packaging
5g
Price
$125
Updated
2025/07/31
TRC
Product number
C367388
Product name
3-Chloroisonicotinaldehyde
Packaging
50mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC32271
Product name
3-Chloro-4-pyridinecarbaldehyde
Packaging
2g
Price
$63
Updated
2021/12/16
AK Scientific
Product number
B373
Product name
3-Chloro-4-pyridinecarboxaldehyde
Packaging
1g
Price
$20
Updated
2021/12/16
More
Less

3-CHLOROISONICOTINALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

off-white to light yellow solid

Synthesis

626-60-8

68-12-2

72990-37-5

The general procedure for the synthesis of 3-chloropyridine-4-carbaldehyde from 3-chloropyridine and N,N-dimethylformamide is as follows: 1. add toluene to a 250 mL round-bottomed flask and cool to -78°C. 2. LDA (11 mL, 22.02 mmol) was slowly added dropwise to a solution of 3-chloropyridine (8.80 mmol) in THF (20 mL) at -78°C and stirred at the same temperature for 1 to 2 hours. 3. DMF (822 μL, 10.56 mmol) was added, then the reaction mixture was brought to room temperature and stirred for 1 hour. 4. Ethyl acetate (EA) and water were added to the reaction mixture and the organic and aqueous layers were separated. 5. The organic solvent was further extracted with the aqueous phase and the organic extracts were combined. 6. The combined organic extracts were dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated in vacuum. 7. The crude product was purified by silica gel column chromatography to afford 3-chloropyridine-4-carbaldehyde (0.33 g, 30-65% yield). 8. The structure of the product was determined by NMR. 8. The structure of the product was confirmed by NMR (400 MHz, CDCl3): δ 7.73 (d, J = 8.0 Hz, 1H), 8.71 (d, J = 4.0 Hz, 1H), 8.81 (s, 1H), 10.52 (s, 1H).

References

[1] Heterocycles, 2006, vol. 67, # 2, p. 543 - 547
[2] Patent: WO2015/88271, 2015, A1. Location in patent: Page/Page column 208

3-CHLOROISONICOTINALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-CHLOROISONICOTINALDEHYDE Suppliers

Americas 1 China 135 Europe 1 Germany 1 India 3 Japan 1 Switzerland 1 United Kingdom 2 United States 15 Global 160
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4999
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Nanjing Raise Pharmatech Co., Ltd.
Tel
025-58649566 15005191108
Fax
025-58649599
Email
sales@njboyuanchem.com
Country
China
ProdList
113
Advantage
60
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Hebei Summedchem Co.,Ltd
Tel
0319-5801333-8008 15630992918
Email
sales@summedchem.com
Country
China
ProdList
965
Advantage
58
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
Tel
+86-021-61727342 13611721451
Fax
021-61294107
Email
chainpharm@163.com
Country
China
ProdList
980
Advantage
58
Shanghai Hong-chuang Pharma Tech Co., Ltd.
Tel
18151128828
Fax
-
Email
hc-sales@foxmail.com
Country
China
ProdList
2647
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Shanghai Hekang Biotechnology Co., Ltd.
Tel
18939837085
Fax
2880152141(QQ)
Email
youchemicals@gmail.com
Country
China
ProdList
1839
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
NINGBO INNO PHARMCHEM CO.,LTD.
Tel
86-574-27787657
Fax
86-574-27912196
Email
info@dearchem.com
Country
China
ProdList
4613
Advantage
58
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9979
Advantage
58
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
CHMA Chemical Technology (Shanghai) Co., Ltd
Tel
021-61556450 15800904410
Fax
021-61556450
Country
China
ProdList
2832
Advantage
58
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Pingguo Pharmaceutical Co., Ltd.
Tel
021-20432229
Fax
QQ2412110556
Email
2412110556@qq.com
Country
China
ProdList
6017
Advantage
55
Nanjing Klender Bio-Technology Co., Ltd.
Tel
025-52343882 18112933882
Fax
025-52343882
Email
sales@kldbio.com
Country
China
ProdList
2019
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
More
Less

View Lastest Price from 3-CHLOROISONICOTINALDEHYDE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
3-CHLOROISONICOTINALDEHYDE 72990-37-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-14
Dideu Industries Group Limited
Product
3-CHLOROISONICOTINALDEHYDE 72990-37-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-02
Career Henan Chemical Co
Product
3-CHLOROISONICOTINALDEHYDE 72990-37-5
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-14

72990-37-5, 3-CHLOROISONICOTINALDEHYDERelated Search:

3-CHLOROISONICOTINALDEHYDE 2,5-Dichloroisonicotinic acid 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 3,5-DICHLORO-4-FORMYL PYRIDINE 3-Chloroisonicotinic acid 2-BROMO-3,5-DICHLOROISONICOTINIC ACID 3-Chloropyridine-2-carboxaldehyde 2-Pyridinecarboxaldehyde, 3,6-dichloro- 2,3-Dichloropyridine-4-carboxaldehyde 2-Chloro-3-pyridinecarboxaldehyde 5-CHLORO-2-FORMYLPYRIDINE 5-CHLORO-PYRIDINE-3-CARBALDEHYDE 2-CHLOROISONICOTINALDEHYDE 4-Chloropyridine-3-carboxaldehyde 2,6-Dichloropyridine-4-carboxaldehyde 2,5-DICHLORO-4-FORMYLPYRIDINE 2-Chloropyridine-5-carbaldehyde 2,4-Dichloropyridine-3-carboxaldehyde

  • 3-CHLOROPYRIDINE-4-CARBOXALDEHYDE
  • 3-CHLOROISONICOTINALDEHYDE
  • 3-CHLORO-4-FORMYLPYRIDINE
  • 3-CHLORO-4-PYRIDINECARBOXALDEHYDE
  • 3-Chloro-4-pyridinecarbaldehyde
  • 3-chloro-2-forMylpyridine-4-carboxylic acid
  • 3-Chloro-pyridine -4-carbaldehyde/3-chloroisonicotinaldehyde
  • 3-Chloro-4-pyridinecarboxaldehyde 97%
  • 3-Chloronocotincarboxaldehyde
  • 3-Chloro-4-pyridinecarboxaldehyde &gt
  • 4-Pyridinecarboxaldehyde, 3-chloro-
  • 3-CHLOROISONICOTINALDEHYDE ISO 9001：2015 REACH
  • 72990-37-5
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyridines
  • Building Blocks
  • Heterocycle-Pyridine series
  • pharmacetical
  • Pyridines