2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
- Product Name
- 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
- CAS No.
- 184416-84-0
- Chemical Name
- 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
- Synonyms
- 2,3-Dichloroisonicotinic;2,3-Dichloroisonicotinicaci;2,3-dichloroisonicotic acid;2,3-DICHLOROISONICOTINIC ACID;2,3- twochlorineisonicotinic acid;2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID;4-Pyridinecarboxylic acid, 2,3-dichloro-;2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID ISO 9001：2015 REACH;2,3-Dichloropyridine-4-carboxylic acid, 4-Carboxy-2,3-dichloropyridine
- CBNumber
- CB1447059
- Molecular Formula
- C6H3Cl2NO2
- Formula Weight
- 192
- MOL File
- 184416-84-0.mol
2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Property
- Melting point:
- 187°
- Boiling point:
- 413.6±40.0 °C(Predicted)
- Density
- 1.612±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 1.46±0.28(Predicted)
- form
- Solid
- Appearance
- Yellow to brown Solid
- CAS DataBase Reference
- 184416-84-0
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 724076
- Product name
- 2,3-Dichloropyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $54
- Updated
- 2022/05/15
- Product number
- D438463
- Product name
- 2,3-DichloroisonicotinicAcid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FD142844
- Product name
- 2,3-Dichloroisonicotinic acid
- Packaging
- 2g
- Price
- $88
- Updated
- 2021/12/16
- Product number
- J98465
- Product name
- 2,3-Dichloroisonicotinicacid
- Packaging
- 10g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 045193
- Product name
- 2,3-Dichloroisonicotinic acid
- Purity
- >95%
- Packaging
- 5g
- Price
- $100
- Updated
- 2021/12/16
2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
2402-77-9
124-38-9
184416-84-0
The general procedure for the synthesis of 2,3-dichloropyridine-4-carboxylic acid from 2,3-dichloropyridine and carbon dioxide was as follows: a hexane solution (31 mL, 50 mmol) of 1.6 M nBuLi was added slowly and dropwise to an anhydrous THF (100 mL) solution of diisopropylamine (7.0 mL, 50 mmol) at -25 °C under inert atmosphere. Subsequently, the reaction mixture was cooled to -78 °C and 2,3-dichloropyridine was added. The reaction mixture was kept stirred at -78 °C for 3 h. It was then poured into solid carbon dioxide and aged for 18 h at room temperature. After the reaction was completed, the mixture was diluted with water (100 mL), washed with ether (3 x 40 mL), then cooled to 0°C and acidified with concentrated HCl (about 5 mL). The acidified mixture was extracted with ether (3 x 50 mL), the organic extracts were combined, dried with anhydrous Na2SO4, filtered and concentrated to give 2,3-dichloropyridine-4-carboxylic acid as a white solid (7.7 g, 80% yield). The product was characterized by 1H NMR (d6-DMSO, 400 MHz): δ 8.49 (d, J = 5.0 Hz, 1H), 7.72 (d, J = 5.0 Hz, 1H).
References
[1] European Journal of Organic Chemistry, 2001, # 7, p. 1371 - 1376
[2] Patent: WO2009/85980, 2009, A1. Location in patent: Page/Page column 46
2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID manufacturers
- Product
- 2,3-Dichloroisonicotinic acid 184416-84-0
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-07-12
- Product
- 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 184416-84-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-03
- Product
- 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 184416-84-0
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kGS
- Release date
- 2018-12-14