ChemicalBook > CAS DataBase List > 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID

2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID

Product Name
2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
CAS No.
184416-84-0
Chemical Name
2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
Synonyms
2,3-Dichloroisonicotinic;2,3-Dichloroisonicotinicaci;2,3-dichloroisonicotic acid;2,3-DICHLOROISONICOTINIC ACID;2,3- twochlorineisonicotinic acid;2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID;4-Pyridinecarboxylic acid, 2,3-dichloro-;2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID ISO 9001：2015 REACH;2,3-Dichloropyridine-4-carboxylic acid, 4-Carboxy-2,3-dichloropyridine
CBNumber
CB1447059
Molecular Formula
C6H3Cl2NO2
Formula Weight
192
MOL File
184416-84-0.mol
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2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Property

Melting point:
187°
Boiling point:
413.6±40.0 °C(Predicted)
Density 
1.612±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
1.46±0.28(Predicted)
form 
Solid
Appearance
Yellow to brown Solid
CAS DataBase Reference
184416-84-0
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
724076
Product name
2,3-Dichloropyridine-4-carboxylic acid
Purity
97%
Packaging
1g
Price
$54
Updated
2022/05/15
TRC
Product number
D438463
Product name
2,3-DichloroisonicotinicAcid
Packaging
100mg
Price
$75
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
Y14236
Product name
2,3-Dichloroisonicotinicacid
Purity
98%
Packaging
1g
Price
$8
Updated
2021/12/16
Apolloscientific
Product number
OR2859
Product name
2,3-Dichloroisonicotinicacid
Packaging
250mg
Price
$15
Updated
2021/12/16
Apolloscientific
Product number
OR2859
Product name
2,3-Dichloroisonicotinicacid
Packaging
1g
Price
$16
Updated
2021/12/16
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2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

2402-77-9

124-38-9

184416-84-0

The general procedure for the synthesis of 2,3-dichloropyridine-4-carboxylic acid from 2,3-dichloropyridine and carbon dioxide was as follows: a hexane solution (31 mL, 50 mmol) of 1.6 M nBuLi was added slowly and dropwise to an anhydrous THF (100 mL) solution of diisopropylamine (7.0 mL, 50 mmol) at -25 °C under inert atmosphere. Subsequently, the reaction mixture was cooled to -78 °C and 2,3-dichloropyridine was added. The reaction mixture was kept stirred at -78 °C for 3 h. It was then poured into solid carbon dioxide and aged for 18 h at room temperature. After the reaction was completed, the mixture was diluted with water (100 mL), washed with ether (3 x 40 mL), then cooled to 0°C and acidified with concentrated HCl (about 5 mL). The acidified mixture was extracted with ether (3 x 50 mL), the organic extracts were combined, dried with anhydrous Na2SO4, filtered and concentrated to give 2,3-dichloropyridine-4-carboxylic acid as a white solid (7.7 g, 80% yield). The product was characterized by 1H NMR (d6-DMSO, 400 MHz): δ 8.49 (d, J = 5.0 Hz, 1H), 7.72 (d, J = 5.0 Hz, 1H).

References

[1] European Journal of Organic Chemistry, 2001, # 7, p. 1371 - 1376
[2] Patent: WO2009/85980, 2009, A1. Location in patent: Page/Page column 46

2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID Suppliers

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View Lastest Price from 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID manufacturers

PNP Biotech Co. Ltd
Product
2,3-Dichloroisonicotinic acid 184416-84-0
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2023-07-12
Dideu Industries Group Limited
Product
2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 184416-84-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-03
Career Henan Chemical Co
Product
2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 184416-84-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kGS
Release date
2018-12-14

184416-84-0, 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACIDRelated Search:

5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid,5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID,5,6-Dichloropyridine-3-carboxylic acid, 98+% 2,6-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 2,4-Dichloropyridine-3-carboxylic acid 3,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID,3,6-dichloropyridine-2-carboxylic acid clopyralid,DICHLOROPYRIDINE ACID [3,6-DICHLOROPYRIDINE-2-CARBOXYLIC ACID ] 2,5-DICHLOROPYRIDINE-3-CARBOXYLIC ACID 3,5-DICHLOROPYRIDINE-2-CARBOXYLIC ACID 3-Amino-2,6-dichloro-isonicotinic acid ethyl ester 2,5-DICHLOROISONICOTINIC ACID / 2,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID,2,5-Dichloropyridine-4-carboxylic acid ,97%,2,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID,2,4-DICHLOROPYRIDINE-5-CARBOXYLIC ACID 2-BROMO-3,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID 3,5-Dichloropyridine-4-carboxylic acid methyl ester, Methyl 3,5-dichloroisonicotinate 2,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID 2,6-Dichloropyridine-4-carboxylic acid methyl ester 4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER 3-Amino-2,6-dichloropyridine-4-carboxylic acid methyl ester Clopyralid (2-hydroxyethyl)ammonium 3,5-Dichloroisonicotinic acid(3,5-Dichloropyridine-4-carboxylic acid),3,5-DICHLOROPYRIDINE-4-CARBOXYLIC ACID

  • 2,3-Dichloroisonicotinic
  • 2,3-DICHLOROISONICOTINIC ACID
  • 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID
  • 2,3-dichloroisonicotic acid
  • 2,3-Dichloropyridine-4-carboxylic acid, 4-Carboxy-2,3-dichloropyridine
  • 2,3- twochlorineisonicotinic acid
  • 4-Pyridinecarboxylic acid, 2,3-dichloro-
  • 2,3-Dichloroisonicotinicaci
  • 2,3-DICHLOROPYRIDINE-4-CARBOXYLIC ACID ISO 9001：2015 REACH
  • 184416-84-0
  • Pyridines
  • intermediate