ChemicalBook > CAS DataBase List > 1H-Benzimidazole-4-carboxylic acid

1H-Benzimidazole-4-carboxylic acid

Product Name
1H-Benzimidazole-4-carboxylic acid
CAS No.
46006-36-4
Chemical Name
1H-Benzimidazole-4-carboxylic acid
Synonyms
4-Carboxy-1H-benzimidazole;Benzimidazole-4-carboxylicacid;4-Benzimidazolecarboxylic acid;1H-BENZIMIDAZOLE-4-CARBOXYLIC ACID;1,3-Benzodiazole-4-carboxylic acid;1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID;benzimidazole-4-carboxylic acid HCl;1H-Benzimidazole-4-carboxylicacid97%;1H-benzo[d]imidazol-7-carboxylic acid;1H-1,3-benzodiazole-4-carboxylic acid
CBNumber
CB7164877
Molecular Formula
C8H6N2O2
Formula Weight
162.15
MOL File
46006-36-4.mol
More
Less

1H-Benzimidazole-4-carboxylic acid Property

Melting point:
>300 °C
Boiling point:
542.5±23.0 °C(Predicted)
Density 
1.506±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
0.17±0.10(Predicted)
Appearance
Off-white to light brown Solid
More
Less

Safety

Hazard Codes 
Xi,N
Risk Statements 
36-51
Safety Statements 
53-26-61
RIDADR 
UN 3077 9 / PGIII
HazardClass 
IRRITANT
HS Code 
29339980
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B197883
Product name
1H-Benzimidazole-4-carboxylicAcid
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
B197883
Product name
1H-Benzimidazole-4-carboxylicAcid
Packaging
500mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
027337
Product name
1H-Benzimidazole-4-carboxylic acid
Packaging
1g
Price
$79
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB05897
Product name
Benzimidazole-4-carboxylic acid
Packaging
1g
Price
$87.5
Updated
2021/12/16
AK Scientific
Product number
W6385
Product name
1H-Benzimidazole-7-carboxylicacid
Packaging
250mg
Price
$104
Updated
2021/12/16
More
Less

1H-Benzimidazole-4-carboxylic acid Chemical Properties,Usage,Production

Synthesis

64-18-6

603-81-6

46006-36-4

To a 4M hydrochloric acid (20 mL) solution of formic acid (0.75 mL, 20.0 mmol) was added 2,3-diaminobenzoic acid (1.00 g, 6.6 mmol). The reaction mixture was heated at reflux temperature for 2 h and subsequently cooled to room temperature. The resulting pink precipitate was separated by filtration and dissolved in hot methanol. Decolorization was carried out by adding activated carbon and stirring for 10 min. The suspension was filtered and the solvent was evaporated under reduced pressure to afford benzimidazole-7-carboxylic acid (0.542 g, 51% yield) as white crystals with a melting point of 266-268 °C. The structure of the product was analyzed by 1H NMR (300 MHz, DMSO-d6) δ 9.64 (s, 1H), 8.11 (dd, J = 8.2, 0.9 Hz, 1H), 8.07 (dd, J = 7.6, 0.9 Hz, 1H), 7.65 (dd, J = 8.2, 7.6 Hz, 1H) and 13C NMR (75 MHz, DMSO-d6 ) δ 265.2, 142.0, 132.3, 129.3, 127.6, 125.6, 119.7, 117.6 confirmed.

References

[1] Journal of Medicinal Chemistry, 2000, vol. 43, # 22, p. 4084 - 4097
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 14, p. 3933 - 3937
[3] Chemische Berichte, 1901, vol. 34, p. 905
[4] Patent: WO2018/42362, 2018, A1. Location in patent: Page/Page column 50

1H-Benzimidazole-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1H-Benzimidazole-4-carboxylic acid Suppliers

China 121 Europe 1 France 2 Germany 2 Hungary 1 India 4 Russia 1 United Kingdom 6 United States 23 Global 161
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Sphinx Scientific Laboratory, LLC
Tel
--
Fax
--
Email
sales@sphinxscientificlab.com
Country
United States
ProdList
3343
Advantage
50
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Anisyn, Inc.
Tel
--
Fax
--
Email
sales@anisyn.com
Country
United States
ProdList
863
Advantage
0
Synthonix
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
1423
Advantage
68
Focus Synthesis LLC
Tel
--
Fax
--
Email
acd@focussynthesis.com
Country
United States
ProdList
2487
Advantage
61
Parkway Scientific
Tel
--
Fax
--
Email
sales@parkwayscientific.com
Country
United States
ProdList
377
Advantage
46
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Aagile Labs Division of Tyger Scientific
Tel
--
Fax
--
Email
tygersci@yahoo.com
Country
United States
ProdList
6568
Advantage
68
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
More
Less

View Lastest Price from 1H-Benzimidazole-4-carboxylic acid manufacturers

Career Henan Chemical Co
Product
1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID 46006-36-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-03-23

46006-36-4, 1H-Benzimidazole-4-carboxylic acidRelated Search:

4-Benzothiazolamine (9CI) 1H-Benzimidazole-2-carboxaldehyde Benzocyclobutyl-1-carboxylic acid Azilsartan Trityl candesartan cilexetil Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Carboxylate 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID 2-ethoxy-3-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]-3h-benzoimidazole-4-carboxylic acid 1H-BENZIMIDAZOLE-2-CARBOXYLIC ACID HYDRATE 1H-Benzimidazole-6-carboxylicacid,1-methyl-(9CI) 2-PHENYL-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID Ethyl 1-methyl-1H-benzimidazole-5-carboxylate 2-PYRIDIN-4-YL-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID 4-Methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate 1-Methyl-1H-benzimidazole-5-carboxylic acid 2-Methylbenzimidazole-5-carboxylic acid 1H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID

  • Benzimidazole-4-carboxylicacid
  • 1H-Benzimidazole-4-carboxylic acid 97%
  • 1H-Benzimidazole-4-carboxylicacid(9CI)
  • 4-Benzimidazolecarboxylic acid
  • 4-Carboxy-1H-benzimidazole
  • 1H-benzo[d]iMidazole-7-carboxylic acid
  • 1H-1,3-benzodiazole-4-carboxylic acid
  • 1H-benzo[d]imidazol-7-carboxylic acid
  • 1H-Benzimidazole-4-carboxylicacid97%
  • 1H-BENZIMIDAZOLE-4-CARBOXYLIC ACID
  • 1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID
  • 1H-benzo[d]imidazole-4-carboxylic acid
  • 1,3-Benzodiazole-4-carboxylic acid
  • benzimidazole-4-carboxylic acid HCl
  • 46006-36-4
  • 46006-36-7
  • Benzoimidazole
  • Building Blocks
  • BENZIMIDAZOLE
  • pharmacetical
  • Carboxylic Acids
  • Imidazoles & Benzimidazoles
  • Carboxylic Acids
  • Imidazoles & Benzimidazoles