ChemicalBook > CAS DataBase List > 2-Amino-4-(trifluoromethyl)pyridine

2-Amino-4-(trifluoromethyl)pyridine

Product Name
2-Amino-4-(trifluoromethyl)pyridine
CAS No.
106447-97-6
Chemical Name
2-Amino-4-(trifluoromethyl)pyridine
Synonyms
4-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE;4-Trifluoromethyl-2-pyridinamine;2-AMino-4-tirfluoroMethylpyridine;-Amino-4-(trifluoromethyl)pyridine;4-Trifluoromethyl-pyridin-2-ylamine;2-AMINO-4-(TRIFLUOROMETHYL)PYRIDINE;2-PyridinaMine, 4-(trifluoroMethyl)-;2-Amino-4-trifluoromethylpyridine HCl;2-Amino-4-(trifluoromethyl)pyridine >2-Amino-4-(trifluoromethyl)pyridine 98%
CBNumber
CB7176955
Molecular Formula
C6H5F3N2
Formula Weight
162.11
MOL File
106447-97-6.mol
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2-Amino-4-(trifluoromethyl)pyridine Property

Melting point:
70-74 °C
Boiling point:
221.3±40.0 °C(Predicted)
Density 
1.368±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
4.55±0.11(Predicted)
form 
Powder, Solid or Crystalline
color 
White to pale brown
BRN 
7869677
InChI
InChI=1S/C6H5F3N2/c7-6(8,9)4-1-2-11-5(10)3-4/h1-3H,(H2,10,11)
InChIKey
RWGBXAQMUBGGKQ-UHFFFAOYSA-N
SMILES
C1(N)=NC=CC(C(F)(F)F)=C1
CAS DataBase Reference
106447-97-6(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi,C
Risk Statements 
25-36/37/38-43-34-22
Safety Statements 
26-36/37-45-36/37/39
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
Hazard Note 
Toxic
HazardClass 
IRRITANT
HazardClass 
6.1
PackingGroup 
II
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
660345
Product name
2-Amino-4-(trifluoromethyl)pyridine
Purity
97%
Packaging
100mg
Price
$161
Updated
2023/06/20
Sigma-Aldrich
Product number
660345
Product name
2-Amino-4-(trifluoromethyl)pyridine
Purity
97%
Packaging
500mg
Price
$244
Updated
2023/06/20
TCI Chemical
Product number
A2168
Product name
2-Amino-4-(trifluoromethyl)pyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$54
Updated
2025/07/31
TCI Chemical
Product number
A2168
Product name
2-Amino-4-(trifluoromethyl)pyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$162
Updated
2025/07/31
TCI Chemical
Product number
A2168
Product name
2-Amino-4-(trifluoromethyl)pyridine
Purity
>98.0%(GC)(T)
Packaging
200mg
Price
$18
Updated
2025/07/31
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2-Amino-4-(trifluoromethyl)pyridine Chemical Properties,Usage,Production

Uses

2-Amino-4-trifluoromethylpyridine is a 2-amino-substituted nitrogen-containing six-membered heterocyclic compound, which is used as an important pharmaceutical intermediate.

Synthesis

2-Amino-4-(trifluoromethyl)pyridine can be synthesized by chemical reaction of 2-fluoro-4-trifluoromethyl-pyridine, acetamidine hydrochloride, NaOH, H2O and dimethyl sulfoxide under certain conditions.

References

[1] Patent: US2010/234607, 2010, A1. Location in patent: Page/Page column 4

2-Amino-4-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-4-(trifluoromethyl)pyridine manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
4-(Trifluoromethyl)pyridin-2-amine 106447-97-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-28
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Amino-4-(trifluoromethyl)pyridine 106447-97-6
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28
Dideu Industries Group Limited
Product
2-Amino-4-(trifluoromethyl)pyridine 106447-97-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-26

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