ChemicalBook > CAS DataBase List > 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride

Product Name
2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride
CAS No.
42036-65-7
Chemical Name
2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride
Synonyms
NSC 12467;NSC 620461;Tramadol EP Impurity E;Tramadol Impurity E HCl;Tramadol EP Impurity E HCl;TraMadol Related CoMpound B;TraMadol Hydrochloride IMpurity-E(EP);Tramadol stg-I mannich HCL EP imp-E RC-B;2-(DIMETHYLAMINOMETHYL) CYCLOHEXANONE HCL;2-(Dimethylaminomethyl)-1-cyclohexanoneHCl
CBNumber
CB7214624
Molecular Formula
C9H18ClNO
Formula Weight
191.7
MOL File
42036-65-7.mol
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2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Property

Melting point:
147-151 °C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Crystalline Powder
color 
White
Water Solubility 
soluble
InChI
InChI=1S/C9H17NO.ClH/c1-10(2)7-8-5-3-4-6-9(8)11;/h8H,3-7H2,1-2H3;1H
InChIKey
CLVHTSWMNNSUSH-UHFFFAOYSA-N
SMILES
C1(CN(C)C)CCCCC1=O.Cl
CAS DataBase Reference
42036-65-7(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29223900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S935484
Product name
2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE
Purity
Aldrich
Packaging
50mg
Price
$179
Updated
2024/03/01
Sigma-Aldrich
Product number
1672621
Product name
2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1210
Updated
2024/03/01
TRC
Product number
B585445
Product name
2-(Bismethyl)aminomethylcyclohexanoneHydrochloride
Packaging
2.5g
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD149699
Product name
2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride
Packaging
1g
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD149699
Product name
2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride
Packaging
2g
Price
$300
Updated
2021/12/16
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2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

An impurity found in Tramadol (T712500).

Synthesis

0.982 g (1.03 mL, 10.0 mmol) cyclohexanone, 0.360 g (12.0 mmol) paraformaldehyde, 0.816 g (10.0 mmol) dimethylammonium chloride and 4 mL ethanol are filled in a 25 mL round bottom flask with reflux condenser and magnetic stir bar. 2 drops of conc. hydrochloric acid is added, and the mixture is heated under stirring for 4 hours under reflux. The hot solution is filtered in a round bottom flask, and the solvent is evaporated by the rotary evaporator. The residue is dissolved in 2 mL ethanol under heating. At room temperature, 20 mL acetone is added to the solution. For complete crystallization, the solution is stored overnight in the freezer compartment. The crystallized crude product 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride is sucked off over a Buechner funnel and dried in the desiccator over silica gel.

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Suppliers

Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58

42036-65-7, 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochlorideRelated Search:


  • 2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE
  • 2-(DIMETHYLAMINOMETHYL)-CYCLOHEXAN-1-ONE HCL
  • 2-(DIMETHYLAMINOMETHYL) CYCLOHEXANONE HCL
  • 2-[(DIMETHYLAMINO)METHYL]CYCLOHEXANONE HYDROCHLORIDE
  • 2-(N,N-DIMETHYLAMINOMETHYL)CYCLOHEXANONE HCL
  • 2-(Dimethylaminomethyl)-1-cyclohexanone, hydrochloride salt
  • 2-(Dimethylamino)methyl cyclhexanone hydrochloride
  • 2-(Dimethylaminomethyl)-1-cyclohexanoneHCl
  • Tramadol EP Impurity E
  • Tramadol Impurity 5(Tramadol EP Impurity E)
  • 2-dimethylaminomethyl cyclohexanon hydrochloride
  • Tramadol Impurity E HCl
  • 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride 98%
  • 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride,98%
  • 2-Dimethyl Amino Methyl Cyclohexanone.HCL (Menich Base)
  • Tramadol Related Compound B (25 mg) (2-(dimethylaminomethyl)-1-cyclohexanone hydrochloride)
  • 2-(DiMethylaMinoMethyl)-1-cyclohexanone hydrochlor
  • 2-(DiMethylaMinoMethyl)-1-cyclohexanone hydrochloride, 98% 1GR
  • 2-(BisMethyl)aMinoMethylcyclohexanone Hydrochloride
  • DiMethyl((2-oxocyclohexyl)Methyl)aMMoniuM Chloride
  • NSC 12467
  • NSC 620461
  • Cyclohexanone, 2-[(diMethylaMino)Methyl]-, hydrochloride
  • TraMadol Hydrochloride IMpurity-E(EP)
  • TraMadol Related CoMpound B
  • Tramadol EP Impurity E HCl
  • 2 - DIMETHYL - METHYL - 1 CYCLOHEXANONE HYDROCHLORIDE
  • Tramadol stg-I mannich HCL EP imp-E RC-B
  • Tramadol EP Impurity E/ Tramadol Related Compound B
  • Tramadol Related Compound B (2-(dimethylaminomethyl)-1-cyclohexanone hydrochloride) (1672621)
  • Tramadol Related Compound B as Hydrochloride
  • Tramadol USP Related Compound B as Hydrochloride
  • Tramadol Hydrochloride EP Impurity E as Hydrochloride
  • Tramadol EP Impurity E HCl (Tramadol USP Related Compound B)
  • Tramadol Hydrochloride Impurity E as Hydrochloride
  • Tramadol Related Compound B (25 mg) (2-[(Dimethylamino)methyl]cyclohexanone hydrochloride)
  • 42036-65-7
  • C9H17NOClH
  • C9H17NOHCl
  • Aminomethyl's
  • Ring Systems