Cyclobutanone

Description References

Product Name: Cyclobutanone
CAS No.: 1191-95-3
Chemical Name: Cyclobutanone
Synonyms: CBON;obutanone;CYCLOBUTANONE;Oxocyclobutane;1-Oxocyclobutane;Cyclobutanone 98%;Cyclobutanone, 98+%;OS-7558Cyclobutanone;cyclobutanone(SALTDATA: FREE);Cyclobutanone, 98%, stabilized
CBNumber: CB7231982
Molecular Formula: C4H6O
Formula Weight: 70.09
MOL File: 1191-95-3.mol

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Cyclobutanone Property

Melting point:: -50.9 °C
Boiling point:: 99 °C (lit.)
Density: 0.938 g/mL at 25 °C (lit.)
refractive index: n20/D 1.421(lit.)
Flash point:: 50 °F
storage temp.: 2-8°C
solubility: soluble in Dichloromethane
form: Liquid
Specific Gravity: 0.938
color: Clear colorless to slightly yellow
Water Solubility: INSOLUBLE
BRN: 1560289
Stability:: Volatile
InChIKey: SHQSVMDWKBRBGB-UHFFFAOYSA-N
CAS DataBase Reference: 1191-95-3(CAS DataBase Reference)
EPA Substance Registry System: Cyclobutanone (1191-95-3)

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Safety

Hazard Codes: F,F+
Risk Statements: 10-11
Safety Statements: 23-24/25-9-33-29-16-7/9
RIDADR: UN 1224 3/PG 3
WGK Germany: 3
TSCA: Yes
HazardClass: 3
PackingGroup: II
HS Code: 29142900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C96001
Product name: Cyclobutanone
Purity: 99%
Packaging: 1g
Price: $33.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: C96001
Product name: Cyclobutanone
Purity: 99%
Packaging: 5g
Price: $159
Updated: 2024/03/01

TCI Chemical

Product number: C1913
Product name: Cyclobutanone (stabilized with Na2CO3)
Purity: >97.0%(GC)
Packaging: 1g
Price: $55
Updated: 2024/03/01

TCI Chemical

Product number: C1913
Product name: Cyclobutanone (stabilized with Na2CO3)
Purity: >97.0%(GC)
Packaging: 5g
Price: $180
Updated: 2024/03/01

Alfa Aesar

Product number: A13068
Product name: Cyclobutanone, 98%, stab. with ca 0.01% BHT
Packaging: 1g
Price: $74.65
Updated: 2024/03/01

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Cyclobutanone Chemical Properties,Usage,Production

Description

Cyclobutanone is an organic compound with a four-membered cyclic ketone. It is used in preparation of cyclobutane derivatives, as a starting material for aminocyclobutanecarboxylic acid through sulfonyloxiranes, to prepare dihydro-furan-2-one in presence of polystyrene-bound phenylselenic acid as catalyst. It is also involved in the photochemical synthesis of nucleoside analogues such as bicyclic nucleosides and isonucleosides. Furthermore, it is used to synthesis fatty acid, 2-oxo-cyclobutane undecanoic acid, which is used in the development of an enzyme-linked immunosorbent assy for the detection of irradiated foods.

References

[1] https://en.wikipedia.org/wiki/Cyclobutanone
[2] https://www.alfa.com/de/catalog/A13068/
[3] https://www.scbt.com/scbt/de/product/2-oxo-cyclobutane-undecanoic-acid-169263-77-8/;jsessionid=Ay2KMCxORq9y-EC6YoYnGGtCnymUGxQi5Lpd-YuCZoW22Re8Xf4w!-2072765631

Chemical Properties

Clear colourless to slightly yellow liquid

Uses

Cyclobutanone is used in preparation of cyclobutane derivatives. It is used as a starting material for aminocyclobutanecarboxylic acid through sulfonyloxiranes. It is also used to prepare dihydro-furan-2-one in presence of polystyrene-bound phenylselenic acid as catalyst. Further, it is involved in the photochemical synthesis of nucleoside analogues such as bicyclic nucleosides and isonucleosides.

Preparation

The Russian chemist Nikolai Kischner first prepared cyclobutanone in 1905. He synthesized cyclobutanone in a low yield from cyclobutanecarboxylic acid in several reaction steps.
Another synthesis of cyclobutanone involves lithium-catalyzed rearrangement of oxaspiropentane, which is formed by epoxidation of the easily accessible methylenecyclopropane.

Purification Methods

Treat cyclobutanone with dilute aqueous KMnO4, dry it with molecular sieves and fractionally distil it. Purify it via the semicarbazone, then regenerate the ketone, dry it (CaSO4), and distil it in a stainless steel spinning-band (or Vigreux, p 11) column. Alternatively, purify it by preparative gas chromatography using a Carbowax 20-M column at 80o. (This treatment also removes acetone). The oxime has m 84-85o (from pet ether) and the semicarbazone has m 212-212-5o (220-221o from MeOH or H2O, Buchanan et al. J Am Chem Soc 64 2701 1942). [Salaun Org Synth 57 36 1977, Fitzer & Quabeck Synthesis 299 1987, Beilstein 7 IV 3.]

Cyclobutanone Preparation Products And Raw materials

Raw materials

Preparation Products

Miewenjuzhi 2-chloro-2-trichloroethyl-3，3-dimethyl cyclobutenone Fenpropathrin Cyfluthrin CYCLOBUTYLHYDRAZINE

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Cyclobutanone Suppliers

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View Lastest Price from Cyclobutanone manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: Cyclobutanone 1191-95-3
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-19

Hangzhou ICH Biofarm Co., Ltd

Product: Cyclobutanone 1191-95-3
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 99.0%min
Supply Ability: 200kg
Release date: 2023-07-03

Zhuozhou Wenxi import and Export Co., Ltd

Product: Cyclobutanone 1191-95-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

1191-95-3, CyclobutanoneRelated Search:

2-Butanone oxime 4-Methyl-2-pentanone Cyclopentanone Sulfolane Cyclobutanol Cyclobutanecarbonyl chloride Cyclobutylamine CYCLOBUTYL-ACETIC ACID Cyclobutanecarboxylic acid Cyclobutanemethanol Cyclobutanecarbonitrile Cycloheptanone (3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one 2-Azetidinone tert-Butyl 3-oxoazetidine-1-carboxylate 3-BENZHYDRYL-CYCLOBUTANONE (3R,4S)-1-Benzoyl-3-(1-ethoxyethoxy)-4-phenyl-2-azetidinone TETRAMETHYL-1,3-CYCLOBUTANEDIONE

CBON

CYCLOBUTANONE

Cyclobutanone, 98+%

Cyclobutanone 98%

Cyclobutanone, 98%, stab. with ca 0.01% BHT

Oxocyclobutane

Cyclobutanone (stabilized with Na2CO3)

Cyclobutanone, 98%, stabilized

OS-7558Cyclobutanone

Cyclobutanone, Stab. With ca 0.01% Bht

cyclobutanone(SALTDATA: FREE)

1-Oxocyclobutane

CYCLOBUTANONE FOR SYNTHESIS 1 ML

CYCLOBUTANONE FOR SYNTHESIS 5 ML

Cyclobutanone, stabilized with &ap:0.01% BHT

obutanone

Cyclobutanone - stabilise 0.01 % BHT

Cyclobutanone (stabilized with Na2CO3)&gt

Cyclobutanone(For export only)

Cyclobutanone, stab. with 0.1% BHT

Cyclobutanone (6CI, 8CI, 9CI, ACI)

1191-95-3

C4H60

Ketones

Organic Building Blocks

C3 to C6

Carbonyl Compounds

Building Blocks

Cyclobutanes & Cyclobutenes

Simple 4-Membered Ring Compounds

C3 to C6

Carbonyl Compounds

Ketones

ketone

Carbonyl Compounds

Pharmaceutical Intermediates

cyclic compounds

bc0001

1191-95-3