SC-51322

Product Name: SC-51322
CAS No.: 146032-79-3
Chemical Name: SC-51322
Synonyms: SC-51322;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[3-[(2-FuranylMethyl) thio]-1-oxopropyl]hydrazide;8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacidhydrazide;Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide
CBNumber: CB7235197
Molecular Formula: C22H20ClN3O4S
Formula Weight: 457.93
MOL File: Mol file

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SC-51322 Property

Melting point:: 112-114°C
RTECS: HQ4002000
storage temp.: Store at +4°C
solubility: DMSO: ≥10mg/mL
form: powder
color: white to off-white

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HazardClass: 6.1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PZ0132
Product name: SC-51322
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $40.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: PZ0132
Product name: SC-51322
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $404
Updated: 2024/03/01

Alfa Aesar

Product number: J67002
Product name: SC-51322, 98%
Packaging: 5mg
Price: $125
Updated: 2021/12/16

Cayman Chemical

Product number: 10010744
Product name: SC-51322
Purity: ≥98%
Packaging: 1mg
Price: $20
Updated: 2024/03/01

Cayman Chemical

Product number: 10010744
Product name: SC-51322
Purity: ≥98%
Packaging: 5mg
Price: $85
Updated: 2024/03/01

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SC-51322 Chemical Properties,Usage,Production

Description

The prostaglandin E₂ (PGE₂) receptor (EP₁) is involved in triggering PGE₂-mediated pain as well as neuronal survival and growth. SC-51322 is a selective EP₁ antagonist that inhibits PGE₂ signaling in a guinea pig ileum muscle strip assay with a pA₂ value of 8.1 and demonstrates analgesic activity in a mouse writhing assay with an ED₅₀ value of 0.9 mg/kg. It is pharmacologically similar to SC-51089, but does not release hydrazine, a known carcinogen to rats, as does SC-51089. SC-51322 potentiates the vasorelaxation of human pulmonary vein induced by PGE₂ with an EC₅₀ value of 7.75 μM.

Chemical Properties

Off-White Solid

Uses

A selective E-prostanoid receptor subtype 1 (EP1) receptor antagonist which shows antihypertensive effects.

storage

Store at -20°C

SC-51322 Preparation Products And Raw materials

Raw materials

Preparation Products

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SC-51322 Suppliers

Canada 1 China 27 India 1 United Kingdom 1 United States 8 Global 38

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146032-79-3, SC-51322Related Search:

13,14-DIHYDROPROSTAGLANDIN E1 PROSTAGLANDIN F1ALPHA Latanoprost Misoprostol Acid PROSTAGLANDIN D2 Sulprostone PROSTAGLANDIN B1 Fluprostenol Prostaglandin F2a PROSTAGLANDIN A1 PROSTAGLANDIN B2 SC-51089 U-75302 L-161,982 6(R)-(4-CARBOXYPHENYLTHIO)-5(S)-HYDROXY-7(E),9(E),11(Z),14(Z)-EICOSATETRAENOIC ACID 11BETA-PROSTAGL AND IN F2ALPHA LEUKOTRIENE B4 DIMETHYL AMIDE LEUKOTRIENE D4

SC-51322

8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacidhydrazide

8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[3-[(2-FuranylMethyl) thio]-1-oxopropyl]hydrazide

Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide

146032-79-3

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