Abacavir 5’-Phosphate
- Product Name
- Abacavir 5’-Phosphate
- CAS No.
- 136470-77-4
- Chemical Name
- Abacavir 5’-Phosphate
- Synonyms
- Abacavir Impurity 13;Abacavir 5'-Phosphate;Abacavir 5’-Phosphate;(1S-cis)-Abacavir Monophosphate;[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate;((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)-;(1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester)
- CBNumber
- CB72502992
- Molecular Formula
- C14H19N6O4P
- Formula Weight
- 366.31
- MOL File
- 136470-77-4.mol
Abacavir 5’-Phosphate Property
- Melting point:
- 189-194°C (dec.)
- Boiling point:
- 749.3±70.0 °C(Predicted)
- Density
- 1.93±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Methanol, Water
- pka
- 1.91±0.10(Predicted)
- form
- Solid
- color
- White
N-Bromosuccinimide Price
- Product number
- A105020
- Product name
- Abacavir5’-Phosphate
- Packaging
- 1mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- A105020
- Product name
- Abacavir5’-Phosphate
- Packaging
- 10mg
- Price
- $625
- Updated
- 2021/12/16
- Product number
- NA16495
- Product name
- Abacavir 5'-phosphate
- Packaging
- 5mg
- Price
- $1051.1
- Updated
- 2021/12/16
- Product number
- 3389CC
- Product name
- Abacavir5'-phosphate
- Packaging
- 5mg
- Price
- $1468
- Updated
- 2021/12/16
- Product number
- NA16495
- Product name
- Abacavir 5'-phosphate
- Packaging
- 10mg
- Price
- $1911
- Updated
- 2021/12/16
Abacavir 5’-Phosphate Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Definition
ChEBI: Abacavir monophosphate is the organic phosphate that is the 5'-monophosphate of abacavir. It has a role as a metabolite. It is a member of 2,6-diaminopurines and an organic phosphate. It is functionally related to an abacavir.
Abacavir 5’-Phosphate Preparation Products And Raw materials
Raw materials
Preparation Products
Abacavir 5’-Phosphate Suppliers
- Tel
- --
- Fax
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- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71