ChemicalBook > CAS DataBase List > Glycitein

Glycitein

Product Name
Glycitein
CAS No.
40957-83-3
Chemical Name
Glycitein
Synonyms
Gycitein;GLYCITEIN;GLYCETEIN; Glicetein;Glycitein-RM;Glycitein(SH);Glycitein, >=98%;Glycitein (15 mg);Glycitein USP/EP/BP;GLYCITEIN,FROMSOYBEAN
CBNumber
CB7253674
Molecular Formula
C16H12O5
Formula Weight
284.26
MOL File
40957-83-3.mol
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Glycitein Property

Melting point:
>300°C
Boiling point:
547.4±50.0 °C(Predicted)
Density 
1.420±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly), DMSO (Slightly)
pka
7.03±0.20(Predicted)
form 
Solid
color 
Light Brown
biological source
synthetic (organic)
InChI
InChI=1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
InChIKey
DXYUAIFZCFRPTH-UHFFFAOYSA-N
SMILES
C1OC2=CC(O)=C(OC)C=C2C(=O)C=1C1=CC=C(O)C=C1
LogP
2.570 (est)
CAS DataBase Reference
40957-83-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

H331Toxic if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89692
Product name
Glycitein
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$316
Updated
2024/03/01
Sigma-Aldrich
Product number
43534
Product name
Glycitein
Purity
analytical standard
Packaging
10mg
Price
$323
Updated
2024/03/01
Sigma-Aldrich
Product number
1295844
Product name
Glycitein
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
15mg
Price
$1110
Updated
2024/03/01
Cayman Chemical
Product number
14162
Product name
Glycitein
Purity
≥98%
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
14162
Product name
Glycitein
Purity
≥98%
Packaging
10mg
Price
$92
Updated
2024/03/01
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Glycitein Chemical Properties,Usage,Production

Description

Glycitein is an O-methylated isoflavone that comprises 5-10% of the total isoflavones in soy food products. This phytoestrogen is reported to have weak estrogenic activity, displacing estradiol binding at the estrogen receptor in vitro with an IC50 value of 3.94 μM. It suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor. It has also been used to attenuate proliferation (10 μM) of aortic smooth muscle cells related to atherosclerotic vascular change in stroke-prone hypertensive rats and to protect against beta amyloid (Aβ)-induced toxicity and oxidative stress (100 μg/ml) in C. elegans expressing human Aβ.

Chemical Properties

Pale Orange Solid

Uses

Glycitein may be used as a reference standard in the determination of glycitein in hydrolyzed dry soya extracts using reversed-phase high-performance liquid chromatography (RP-HPLC).

Uses

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Uses

The compund shows an anti-cancer activity, plasma cholesterol reduction, reduction in postmenopausal bone loss

Definition

ChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis.

General Description

Glycitein is an isoflavone found in soy food products.

Biochem/physiol Actions

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein Preparation Products And Raw materials

Raw materials

Preparation Products

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Glycitein Suppliers

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View Lastest Price from Glycitein manufacturers

Henan Fengda Chemical Co., Ltd
Product
Glycitein 40957-83-3
Price
US $8.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-29
Shanghai Standard Technology Co., Ltd.
Product
Glycitein 40957-83-3
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-31
Zhuozhou Wenxi import and Export Co., Ltd
Product
Glycitein 40957-83-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

40957-83-3, GlyciteinRelated Search:

Methoxydiethylborane Riboflavin 5'-Monophosphate Sodium Salt Triclosan Anisole p-Anisidine Solvent Red 43 Emodin Chrysin Curcumin (Trifluoromethoxy)benzene 1-Hydroxyethylidene-1,1-diphosphonic acid Theaflavin Riboflavin GLYCITEIN 7,4'-DIMETHYL ETHER Tectorigenin Tectoridin WISTIN Glycitin

  • GLYCETEIN
  • GLYCITEIN
  • 4',7-DIHYDROXY-6-METHOXYISOFLAVONE
  • 4,7-DIHYDROXY-6-METHOXYISOFLAVONE
  • 7,4'-DIHYDROXY-6-METHOXYISOFLAVONE
  • Glicetein
  • 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-
  • 7-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-4-one
  • Glycitein, >=98%
  • Glycitein, 98%, from soybean
  • 4μ,7-Dihydroxy-6-methoxyisoflavone, Glycetein
  • 3-(4-Hydroxyphenyl)-6-methoxy-7-hydroxy-4H-1-benzopyran-4-one
  • Glycitein,4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein
  • Glycitein (15 mg)
  • GLYCITEIN,FROMSOYBEAN
  • Glycitein USP/EP/BP
  • Gycitein
  • Glycitein, ≥97% (HPLC)
  • Glycitein (P) (Compendial Traceable)
  • 4',7- Dihydroxy -6-methoxy Isoflavone (or ) GLYCITIN
  • 7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
  • GLYCITEIN (Compendial Traceable)
  • Glycitein(SH)
  • Glycitein-RM
  • Coumarin Impurity 9 (Coumarin 30)
  • Glycitein, 10 mM in DMSO
  • 40957-83-3
  • 40957-83-0
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Biochemicals and Reagents
  • BioChemical
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • The group of Daidzin
  • inhibitor
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Iso-Flavones