2,5-Bis(trifluoromethyl)nitrobenzene
- Product Name
- 2,5-Bis(trifluoromethyl)nitrobenzene
- CAS No.
- 320-88-7
- Chemical Name
- 2,5-Bis(trifluoromethyl)nitrobenzene
- Synonyms
- 2,5-DI(TRIFLUOROMETHYL)NITROBENZENE;2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE;2-NITRO-1,4-BIS(TRIFLUOROMETHYL)BENZENE;1-NITRO-2,5-BIS(TRIFLUOROMETHYL)BENZENE;1,4-BIS(TRIFLUOROMETHYL)-2-NITROBENZENE;2,5-Bis(trifluoromethyl)nitrobenzene97%;2,5-Bis(trifluoromethyl)nitrobenzene 97%;Benzene, 2-nitro-1,4-bis(trifluoromethyl)-;1-Nitro-2,5-bis(trifluoromethyl)benzene>2-Nitro-1,4-bis(trifluoromethyl)benzene,98%
- CBNumber
- CB7281886
- Molecular Formula
- C8H3F6NO2
- Formula Weight
- 259.11
- MOL File
- 320-88-7.mol
2,5-Bis(trifluoromethyl)nitrobenzene Property
- Boiling point:
- 70-75 °C (15 mmHg)
- Density
- 1.57
- refractive index
- 1.4235-1.4255
- Flash point:
- 77 °C
- storage temp.
- 2-8°C
- solubility
- Chloroform, Methanol
- form
- Liquid
- color
- Pale yellow to yellow
- Sensitive
- Light Sensitive
- CAS DataBase Reference
- 320-88-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38
- Safety Statements
- 37/39-26-60-37-23
- HazardClass
- TOXIC
- HS Code
- 29049090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B2546
- Product name
- 1-Nitro-2,5-bis(trifluoromethyl)benzene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $26
- Updated
- 2025/07/31
- Product number
- B2546
- Product name
- 1-Nitro-2,5-bis(trifluoromethyl)benzene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- B591783
- Product name
- 2,5-Bis(Trifluoromethyl)nitrobenzene
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- HCH0017778
- Product name
- 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $621.16
- Updated
- 2021/12/16
- Product number
- HCH0017778
- Product name
- 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $925.39
- Updated
- 2021/12/16
2,5-Bis(trifluoromethyl)nitrobenzene Chemical Properties,Usage,Production
Chemical Properties
clear yellow liquid
Uses
2,5-Bis(Trifluoromethyl)nitrobenzene can be prepared to be used as antifungal agents.
Synthesis
433-19-2
320-88-7
General Steps: Example 2: Using 2,3-difluorotoluene as raw material, adopting the same reaction conditions as in Example 1, but replacing 96 mass% sulfuric acid with fuming sulfuric acid with a sulfur trioxide concentration of 10 mass%, the reaction was stirred at 80° C. for 8 hours to obtain 2,5-bis(trifluoromethyl)nitrobenzene in a yield of 68.7%. Example 4: Using 2,3-difluorotoluene as raw material, the same reaction conditions as in Example 1 were used, but 96 mass% of sulfuric acid was replaced with fuming sulfuric acid having a sulfur trioxide concentration of 10 mass%, and 97 mass% of fuming nitric acid was replaced with 98 mass% of concentrated nitric acid, and the reaction was stirred at 80°C for 10 hours to obtain 2,5-bis(trifluoromethyl)nitrobenzene in a yield of 65.3%. Example 7 (Comparative Example): Using 2,3-difluorotoluene as raw material and the same reaction conditions as in Example 1, but replacing 96 mass% sulfuric acid with fuming sulfuric acid with a sulfur trioxide concentration of 24 mass%, 2,5-bis(trifluoromethyl)nitrobenzene was obtained in a yield of 32.5%.
References
[1] Patent: EP1468983, 2004, A1. Location in patent: Page 6
[2] Patent: EP1468983, 2004, A1. Location in patent: Page 5; 6
[3] Journal of the American Chemical Society, 1953, vol. 75, p. 4967
[4] Journal of Organic Chemistry, 1995, vol. 60, # 22, p. 7348 - 7350
[5] Patent: WO2011/150156, 2011, A2. Location in patent: Page/Page column 132
2,5-Bis(trifluoromethyl)nitrobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
2,5-Bis(trifluoromethyl)nitrobenzene Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
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- Fax
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- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
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- Fax
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- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
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View Lastest Price from 2,5-Bis(trifluoromethyl)nitrobenzene manufacturers
- Product
- 2,5-Bis(trifluoromethyl)nitrobenzene 320-88-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-09