ChemicalBook > CAS DataBase List > Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
- Product Name
- Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
- CAS No.
- 219649-07-7
- Chemical Name
- Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
- Synonyms
- Labetuzumab;Labetuzumab (anti-CEACAM5);Research Grade Labetuzumab;IMMU-14|||hMN-14|||IMMU-100;Research Grade Labetuzumab(DHC21001);Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer
- CBNumber
- CB73206493
- Formula Weight
- 0
- MOL File
- Mol file
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Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Property
- form
- Liquid
- color
- Colorless to light yellow
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Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Chemical Properties,Usage,Production
Uses
Treatment of colorectal cancer (humanized monoclonal antibody hMN-14 targeting CEA- positive cancers).
brand name
CEA-CIDE (Immunomedics).
in vivo
Labetuzumab (0.5 mg/rat; i.v.; single) inhibits tumor growth in vivo[1].
| Animal Model: | Female nu/nu mice (6 to 8-week-old; inject TT cells)[1]. |
| Dosage: | 0.5 mg/rat |
| Administration: | Intravenous injection; single (1 day post-tumor cell injection) |
| Result: | Significantly delaied growth of tumor, and led to 64%-70% inhibition of tumor size between days 32 and 60. |
Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Preparation Products And Raw materials
Raw materials
Preparation Products
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Immunoglobulin G,anti-(human carcinoembryonic antigen) (human-mouse monoclonal hMN-14 g-chain), disulfide withhuman-mouse monoclonal hMN-14 k-chain, dimer Suppliers
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