ChemicalBook > CAS DataBase List > (R)-1-Boc-3-Aminopiperidine

(R)-1-Boc-3-Aminopiperidine

Product Name
(R)-1-Boc-3-Aminopiperidine
CAS No.
188111-79-7
Chemical Name
(R)-1-Boc-3-Aminopiperidine
Synonyms
tert-butyl (R)-3-aminopiperidine-1-carboxylate;(R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;tert-Butyl (3R)-3-aminopiperidine-1-carboxylate;(R)-3-AMINO-1-N-BOC-PIPERIDINE;LigliptinImpurity69;(R)-BOC-PIP(3-NH2) HCL;Linagliptin Impurity 69;Linagliptin Impurity 98;(R)-1-BOC-3-PIPERIDINAMINE;(R)-1-Boc-3-AMinopiperidin
CBNumber
CB7326716
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
188111-79-7.mol
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(R)-1-Boc-3-Aminopiperidine Property

alpha 
28.5 º (c=1, DMF)
Boiling point:
277.3±33.0 °C(Predicted)
Density 
1.041±0.06 g/cm3(Predicted)
refractive index 
1.4730
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
pka
10.35±0.20(Predicted)
form 
Liquid
color 
Colorless to pale yellow
optical activity
[α]/D -28.5±2°, c = 1 in DMF
Water Solubility 
Immiscible with water.
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChIKey
AKQXKEBCONUWCL-MRVPVSSYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
CAS DataBase Reference
188111-79-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
RIDADR 
UN2735
WGK Germany 
3
F 
10-34
HazardClass 
8
PackingGroup 
III
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
07858
Product name
(R)-(−)-3-Amino-1-Boc-piperidine
Purity
≥98.0% (TLC)
Packaging
1G-F
Price
$283
Updated
2024/03/01
Sigma-Aldrich
Product number
07858
Product name
(R)-(−)-3-Amino-1-Boc-piperidine
Purity
≥98.0% (TLC)
Packaging
1g
Price
$272
Updated
2023/01/07
Alfa Aesar
Product number
H26937
Product name
(R)-(-)-3-Amino-1-Boc-piperidine, 98%
Packaging
5g
Price
$392.65
Updated
2024/03/01
TRC
Product number
B692215
Product name
tert-Butyl(R)-3-Aminopiperidine-1-carboxylate
Packaging
1g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA10567
Product name
(3R)-3-Amino-N1-Boc-piperidine
Packaging
25g
Price
$200
Updated
2021/12/16
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(R)-1-Boc-3-Aminopiperidine Chemical Properties,Usage,Production

Chemical Properties

Yellow liquid

Uses

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

Uses

(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.

General Description

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

(R)-1-Boc-3-Aminopiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-Boc-3-Aminopiperidine Suppliers

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View Lastest Price from (R)-1-Boc-3-Aminopiperidine manufacturers

Xingtai Haoxun Import and Export Trade Co., Ltd.
Product
(R)-1-Boc-3-Aminopiperidine 188111-79-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10tons
Release date
2020-07-17
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
(R)-1-Boc-3-Aminopiperidine 188111-79-7
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-14
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
tert-butyl (3R)-3-aminopiperidine-1-carboxylate 188111-79-7
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10KG
Release date
2021-09-17

188111-79-7, (R)-1-Boc-3-AminopiperidineRelated Search:

Glycine Haloperidol 3-AMINOPIPERIDINE tert-Butyl carbazate N-Carbobenzyloxyglycine tert-Butanol 6-Aminocaproic acid ALTRENOGEST Tris(hydroxymethyl)aminomethane 8-Bromo-3-methyl-xanthine 2-Aminoacetophenone (R)-Boc-Nipecotic acid Diphenoxylate 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)- 1,1'-Diacetylferrocene (R)-1-Boc-3-Aminopiperidine-3-carboxylic acid (R)-1-N-BOC-3-METHYLAMINO PIPERIDINE Piperidine

  • tert-Butyl (3R)-3-aminopiperidine-1-carboxylate
  • (R)-3-Aminopiperidine, N1-BOC protected
  • (R)-1-t-Butyloxycarbonyl-3-aminopiperidine hydrochloride
  • (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate
  • (R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine
  • 1-TERT-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE
  • 1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester,(3R)-(9CI)
  • (R)-3-AMINO-N-BOC-PIPERIDINE
  • (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HCL
  • (R)-1-TERT-BUTYLOXYCARBONYL-3-AMINOPIPERIDINE HYDROCHLORIDE
  • (R)-1-BOC-3-PIPERIDINAMINE
  • (R)-1-BOC-3-AMNIOPIPERIDINE
  • (R)-1-BOC-3-AMINOPIPERIDINE
  • (R)-1-BOC-3-AMINOPIPERIDINE HCL
  • (R)-1-N-BOC-3-AMINO PIPERIDINE
  • (R)-N-BOC-3-AMINOPIPERIDINE
  • (R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE
  • TERT-BUTYL (R)-3-AMINO-1-PIPERIDINECARBOXYLATE
  • 2-Methyl-2-propanyl (3S)-3-amino-1-piperidinecarboxylate
  • (3R)-3-Aminopiperidine, N1-BOC protected
  • (3R)-3-Amino-N1-Boc-piperidine
  • (R)-1-Boc-3-aMinopiperidi...
  • (R)-1-Boc-3-AMinopiperidin
  • tert-Butyl (3R)-3-aminopiperidine-1-carboxylate, (3R)-3-Amino-1-(tert-butoxycarbonyl)piperidine
  • (R)-1-Boc-3-AMniopiperidine SynonyMs (R)-3-AMino-1-N-Boc-piperidine
  • (R)-tert-Butyl 3-aMinopiperidine-1-carboxylate, >95%
  • (R)-(-)-3-Amino-1-Boc-piperidine,98%
  • tert-butyl (R)-3-aminopiperidine-1-carboxylate
  • (R)-1-Boc-3-aminopiperidine,99%e.e.
  • 1-T-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE
  • 1-tert-butyloxycarbonyl-3-r-aminopiperidine
  • 1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER, (3R)-
  • (R)-BOC-PIP(3-NH2) HCL
  • (R)-3-AMINO-1-N-BOC-PIPERIDINE
  • (R)-3-AMINO-1-BOC-PIPERIDINE
  • (R)-3-AMINO-1-BOC-PIPERIDINE HYDROCHLORIDE
  • (R)-1-tert-butoxycarbonyl-3-aminoperidol
  • 3-aminopiperidine-1-carboxyL
  • Linagliptin Impurity 69
  • Linagliptin N-t-BOC Piperidine Impurity
  • Linagliptin Impurity 98
  • (R)-3-aminopiperidine-1-carboxylate
  • ert-butyl(3R)-3-aminopiperidine-1-carboxylate
  • (R)-1-Boc-3-Aminopiperidine USP/EP/BP
  • LigliptinImpurity69
  • (R)-tert-Butyl 3-amino-piperidin-1-carboxylate
  • 188111-79-7
  • 1152113-32-0
  • 1118-90-1
  • C10H21ClN2O2
  • CHIRAL CHEMICALS
  • Piperidines
  • Piperidine Series
  • pharmacetical
  • Piperidine
  • AMINOACID