ChemicalBook > CAS DataBase List > (R)-1-Boc-3-Aminopiperidine

(R)-1-Boc-3-Aminopiperidine

Product Name
(R)-1-Boc-3-Aminopiperidine
CAS No.
188111-79-7
Chemical Name
(R)-1-Boc-3-Aminopiperidine
Synonyms
tert-butyl (R)-3-aminopiperidine-1-carboxylate;(R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;tert-Butyl (3R)-3-aminopiperidine-1-carboxylate;(R)-3-AMINO-1-N-BOC-PIPERIDINE;LigliptinImpurity69;(R)-BOC-PIP(3-NH2) HCL;Linagliptin Impurity 69;Linagliptin Impurity 98;(R)-1-BOC-3-PIPERIDINAMINE;(R)-1-Boc-3-AMinopiperidin
CBNumber
CB7326716
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
188111-79-7.mol
More
Less

(R)-1-Boc-3-Aminopiperidine Property

alpha 
28.5 º (c=1, DMF)
Boiling point:
277.3±33.0 °C(Predicted)
Density 
1.041±0.06 g/cm3(Predicted)
refractive index 
1.4730
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
pka
10.35±0.20(Predicted)
form 
Liquid
color 
Colorless to pale yellow
optical activity
[α]/D -28.5±2°, c = 1 in DMF
Water Solubility 
Immiscible with water.
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChIKey
AKQXKEBCONUWCL-MRVPVSSYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
CAS DataBase Reference
188111-79-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
RIDADR 
UN2735
WGK Germany 
3
F 
10-34
HazardClass 
8
PackingGroup 
III
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
07858
Product name
(R)-(−)-3-Amino-1-Boc-piperidine
Purity
≥98.0% (TLC)
Packaging
1G-F
Price
$283
Updated
2024/03/01
Sigma-Aldrich
Product number
07858
Product name
(R)-(−)-3-Amino-1-Boc-piperidine
Purity
≥98.0% (TLC)
Packaging
1g
Price
$272
Updated
2023/01/07
Alfa Aesar
Product number
H26937
Product name
(R)-(-)-3-Amino-1-Boc-piperidine, 98%
Packaging
5g
Price
$392.65
Updated
2024/03/01
TRC
Product number
B692215
Product name
tert-Butyl(R)-3-Aminopiperidine-1-carboxylate
Packaging
1g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA10567
Product name
(3R)-3-Amino-N1-Boc-piperidine
Packaging
25g
Price
$200
Updated
2021/12/16
More
Less

(R)-1-Boc-3-Aminopiperidine Chemical Properties,Usage,Production

Chemical Properties

Yellow liquid

Uses

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

Uses

(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.

General Description

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

(R)-1-Boc-3-Aminopiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-1-Boc-3-Aminopiperidine Suppliers

Canada 1 China 296 Europe 3 France 2 Germany 8 India 6 Japan 3 Switzerland 2 United Kingdom 16 United States 60 Global 397
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
Reax Chemicals
Tel
--
Fax
--
Country
India
ProdList
4217
Advantage
58
Trignokem International.
Tel
--
Fax
--
Email
ignokem@gmail.com
Country
India
ProdList
233
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
Trignokem International
Tel
--
Fax
--
Email
info@trignokem.com
Country
India
ProdList
380
Advantage
50
More
Less

View Lastest Price from (R)-1-Boc-3-Aminopiperidine manufacturers

Xingtai Haoxun Import and Export Trade Co., Ltd.
Product
(R)-1-Boc-3-Aminopiperidine 188111-79-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10tons
Release date
2020-07-17
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
(R)-1-Boc-3-Aminopiperidine 188111-79-7
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-14
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
tert-butyl (3R)-3-aminopiperidine-1-carboxylate 188111-79-7
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10KG
Release date
2021-09-17

188111-79-7, (R)-1-Boc-3-AminopiperidineRelated Search:

Glycine Haloperidol 3-AMINOPIPERIDINE tert-Butyl carbazate N-Carbobenzyloxyglycine tert-Butanol 6-Aminocaproic acid ALTRENOGEST Tris(hydroxymethyl)aminomethane 8-Bromo-3-methyl-xanthine 2-Aminoacetophenone (R)-Boc-Nipecotic acid Diphenoxylate 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)- 1,1'-Diacetylferrocene (R)-1-Boc-3-Aminopiperidine-3-carboxylic acid (R)-1-N-BOC-3-METHYLAMINO PIPERIDINE Piperidine

  • tert-Butyl (3R)-3-aminopiperidine-1-carboxylate
  • (R)-3-Aminopiperidine, N1-BOC protected
  • (R)-1-t-Butyloxycarbonyl-3-aminopiperidine hydrochloride
  • (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate
  • (R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine
  • 1-TERT-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE
  • 1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester,(3R)-(9CI)
  • (R)-3-AMINO-N-BOC-PIPERIDINE
  • (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HCL
  • (R)-1-TERT-BUTYLOXYCARBONYL-3-AMINOPIPERIDINE HYDROCHLORIDE
  • (R)-1-BOC-3-PIPERIDINAMINE
  • (R)-1-BOC-3-AMNIOPIPERIDINE
  • (R)-1-BOC-3-AMINOPIPERIDINE
  • (R)-1-BOC-3-AMINOPIPERIDINE HCL
  • (R)-1-N-BOC-3-AMINO PIPERIDINE
  • (R)-N-BOC-3-AMINOPIPERIDINE
  • (R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE
  • TERT-BUTYL (R)-3-AMINO-1-PIPERIDINECARBOXYLATE
  • 2-Methyl-2-propanyl (3S)-3-amino-1-piperidinecarboxylate
  • (3R)-3-Aminopiperidine, N1-BOC protected
  • (3R)-3-Amino-N1-Boc-piperidine
  • (R)-1-Boc-3-aMinopiperidi...
  • (R)-1-Boc-3-AMinopiperidin
  • tert-Butyl (3R)-3-aminopiperidine-1-carboxylate, (3R)-3-Amino-1-(tert-butoxycarbonyl)piperidine
  • (R)-1-Boc-3-AMniopiperidine SynonyMs (R)-3-AMino-1-N-Boc-piperidine
  • (R)-tert-Butyl 3-aMinopiperidine-1-carboxylate, >95%
  • (R)-(-)-3-Amino-1-Boc-piperidine,98%
  • tert-butyl (R)-3-aminopiperidine-1-carboxylate
  • (R)-1-Boc-3-aminopiperidine,99%e.e.
  • 1-T-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE
  • 1-tert-butyloxycarbonyl-3-r-aminopiperidine
  • 1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER, (3R)-
  • (R)-BOC-PIP(3-NH2) HCL
  • (R)-3-AMINO-1-N-BOC-PIPERIDINE
  • (R)-3-AMINO-1-BOC-PIPERIDINE
  • (R)-3-AMINO-1-BOC-PIPERIDINE HYDROCHLORIDE
  • (R)-1-tert-butoxycarbonyl-3-aminoperidol
  • 3-aminopiperidine-1-carboxyL
  • Linagliptin Impurity 69
  • Linagliptin N-t-BOC Piperidine Impurity
  • Linagliptin Impurity 98
  • (R)-3-aminopiperidine-1-carboxylate
  • ert-butyl(3R)-3-aminopiperidine-1-carboxylate
  • (R)-1-Boc-3-Aminopiperidine USP/EP/BP
  • LigliptinImpurity69
  • (R)-tert-Butyl 3-amino-piperidin-1-carboxylate
  • 188111-79-7
  • 1152113-32-0
  • 1118-90-1
  • C10H21ClN2O2
  • CHIRAL CHEMICALS
  • Piperidines
  • Piperidine Series
  • pharmacetical
  • Piperidine
  • AMINOACID