ChemicalBook > CAS DataBase List > (R)-1-Boc-3-Aminopiperidine
(R)-1-Boc-3-Aminopiperidine
- Product Name
- (R)-1-Boc-3-Aminopiperidine
- CAS No.
- 188111-79-7
- Chemical Name
- (R)-1-Boc-3-Aminopiperidine
- Synonyms
- tert-butyl (R)-3-aminopiperidine-1-carboxylate;(R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;tert-Butyl (3R)-3-aminopiperidine-1-carboxylate;(R)-3-AMINO-1-N-BOC-PIPERIDINE;LigliptinImpurity69;(R)-BOC-PIP(3-NH2) HCL;Linagliptin Impurity 69;Linagliptin Impurity 98;(R)-1-BOC-3-PIPERIDINAMINE;(R)-1-Boc-3-AMinopiperidin
- CBNumber
- CB7326716
- Molecular Formula
- C10H20N2O2
- Formula Weight
- 200.28
- MOL File
- 188111-79-7.mol
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(R)-1-Boc-3-Aminopiperidine Property
- alpha
- 28.5 º (c=1, DMF)
- Boiling point:
- 277.3±33.0 °C(Predicted)
- Density
- 1.041±0.06 g/cm3(Predicted)
- refractive index
- 1.4730
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
- pka
- 10.35±0.20(Predicted)
- form
- Liquid
- color
- Colorless to pale yellow
- optical activity
- [α]/D -28.5±2°, c = 1 in DMF
- Water Solubility
- Immiscible with water.
- Sensitive
- Moisture Sensitive
- InChI
- InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
- InChIKey
- AKQXKEBCONUWCL-MRVPVSSYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
- CAS DataBase Reference
- 188111-79-7(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- RIDADR
- UN2735
- WGK Germany
- 3
- F
- 10-34
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29333990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 07858
- Product name
- (R)-(−)-3-Amino-1-Boc-piperidine
- Purity
- ≥98.0% (TLC)
- Packaging
- 1G-F
- Price
- $283
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 07858
- Product name
- (R)-(−)-3-Amino-1-Boc-piperidine
- Purity
- ≥98.0% (TLC)
- Packaging
- 1g
- Price
- $272
- Updated
- 2023/01/07
Alfa Aesar
- Product number
- H26937
- Product name
- (R)-(-)-3-Amino-1-Boc-piperidine, 98%
- Packaging
- 5g
- Price
- $392.65
- Updated
- 2024/03/01
TRC
- Product number
- B692215
- Product name
- tert-Butyl(R)-3-Aminopiperidine-1-carboxylate
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA10567
- Product name
- (3R)-3-Amino-N1-Boc-piperidine
- Packaging
- 25g
- Price
- $200
- Updated
- 2021/12/16
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(R)-1-Boc-3-Aminopiperidine Chemical Properties,Usage,Production
Chemical Properties
Yellow liquid
Uses
(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.
Uses
(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.
General Description
(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.
(R)-1-Boc-3-Aminopiperidine Preparation Products And Raw materials
Raw materials
Preparation Products
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(R)-1-Boc-3-Aminopiperidine Suppliers
- Tel
- --
- Fax
- --
- christof.senn@cslabs.ch
- Country
- Switzerland
- ProdList
- 502
- Advantage
- 58
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
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View Lastest Price from (R)-1-Boc-3-Aminopiperidine manufacturers
Xingtai Haoxun Import and Export Trade Co., Ltd.
- Product
- (R)-1-Boc-3-Aminopiperidine 188111-79-7
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2020-07-17
Hong Kong Tiansheng New Material Trading Co., Ltd
- Product
- (R)-1-Boc-3-Aminopiperidine 188111-79-7
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2021-09-14
Hong Kong Tiansheng New Material Trading Co., Ltd
- Product
- tert-butyl (3R)-3-aminopiperidine-1-carboxylate 188111-79-7
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10KG
- Release date
- 2021-09-17
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