Chloramine-T

ChemicalBook > CAS DataBase List > Chloramine-T

Product Name: Chloramine-T
CAS No.: 127-65-1
Chemical Name: Chloramine-T
Synonyms: CHLORAMINE T;Tosylchloramide sodium;SodiuM chloro(tosyl)aMide;halamid;chlorazan;MI 9;NF X;anexol;GANSIL;clorina
CBNumber: CB7344990
Molecular Formula: C7H7ClNNaO2S
Formula Weight: 227.64
MOL File: 127-65-1.mol

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Chloramine-T Property

Melting point:: 167-170 °C(lit.)
Density: 1.401[at 20℃]
vapor pressure: 0Pa at 25℃
storage temp.: Sealed in dry,2-8°C
solubility: H₂O: >100 mg/mL
pka: 0.39[at 20 ℃]
form: Solid
color: White to off-white
Water Solubility: 150g/L at 25℃
Stability:: Stable. Incompatible with strong oxidizing agents. May decompose violently if heated above 130 C. May decompose on exposure to air.
InChI: InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1
InChIKey: VDQQXEISLMTGAB-UHFFFAOYSA-N
SMILES: S(=O)(=O)(N(Cl)[Na])C1C=CC(C)=CC=1
LogP: -1.3 at 20℃
CAS DataBase Reference: 127-65-1(CAS DataBase Reference)
EPA Substance Registry System: Chloramine T (127-65-1)

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Safety

Hazard Codes: C,Xn
Risk Statements: 22-31-34-42
Safety Statements: 22-26-36/37/39-45-7-1/2
RIDADR: UN 3263 8/PG 3
WGK Germany: 2
HazardClass: 8
PackingGroup: III
HS Code: 29242990
Hazardous Substances Data: 127-65-1(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S470155
Product name: AKTIVIN
Purity: AldrichCPR
Packaging: 1G
Price: $179
Updated: 2024/03/01

Matrix Scientific

Product number: 099856
Product name: Sodium chloro(tosyl)amide
Purity: 95+%
Packaging: 100g
Price: $285
Updated: 2021/12/16

ChemScene

Product number: CS-4435
Product name: Chloramine-T
Purity: ≥98.0%
Packaging: 500mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-4435
Product name: Chloramine-T
Purity: ≥98.0%
Packaging: 1g
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 099856
Product name: Sodium chloro(tosyl)amide
Purity: 95+%
Packaging: 25g
Price: $118
Updated: 2021/12/16

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Chloramine-T Chemical Properties,Usage,Production

Description

The sodium salt of p-toluenesulfochloramide, commonly known as chloramine-T, exerts strong oxidizing action in both acidic and alkaline media and thus has been widely used for the oxidimetric determination of a large number of inorganic and organic substances. Oxidation of some aldehydes by chloramine-T has been reported to occur quantitatively in an alkaline solution, giving the corresponding acid as the end product. Both direct and indirect methods have been carried out to estimate aldehydes by chloramine-T. Chloramine-T (CAT) is also commonly used in radiolabeling bioactive molecules by halogenation. CAT is used to release radioactive elemental iodine by oxidation of its salts. Unfortunately, CAT is a strong oxidizing agent and can cause significant damage to peptides and proteins. This may lower the yield of the iodination reaction and may produce undesirable side products[1-2].

Chemical Properties

white or yellow powder with a chlorine-like odour

Uses

antiseptic, disinfestant, antiproliferative

Uses

This disinfectant is for external use only, it can exterminate bacteria, viruses, fungi, spore. The action principle is that chlorine can sterilize slowly and lastingly, and also can dissolve necrotic tissue, chlorine come from hypochlorous acid which is produced by Chloramine-T solution. Apply to disinfect drinking water container,food,all kind of tableware, fruits and vegetables,and cleaning wound, mucous membrane.

Uses

sterilizer, antiseptic, disinfectant, and chemical reagent in the medical and pharmaceutical fields.

Definition

ChEBI: An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.

Flammability and Explosibility

Not classified

Safety Profile

Poison by parenteral and intravenous routes. Human mutagenic data reported. When heated to decomposition it emits toxic fumes of Cl-, SOx, Na2O, and NOx. See also SULFONATES and CHLORIDES.

Synthesis

Chloramine-T is prepared in 75 – 95 % yield by passing chlorine into a sodium hydroxide solution of p-toluenesulfonamide. It is a strong electrolyte in acid solution and a good oxidizing agent in base. It is fairly soluble in water, and practically insoluble in benzene, chloroform, and ether. The compound reacts readily with mustard gas to yield a harmless crystalline sulfimide; chloramine-T derivatives are being studied as protective agents against poison gas.

References

[1] M. C. Agrawal, S. P. Mushran. "Mechanism of Oxidation of some Aliphatic Aldehydes by Chloramine-T." Zeitschrift für Naturforschung B 20 1 (1972): 401–404.
[2] B M Tashtoush. "Chloramine-T in radiolabeling techniques. IV. Penta-O-acetyl-N-chloro-N-methylglucamine as an oxidizing agent in radiolabelling techniques." Analytical biochemistry 288 1 (2001): 16–21.

Chloramine-T Preparation Products And Raw materials

Raw materials

Sodium hypochlorite Saccharin Water Tosyl chloride

Preparation Products

Hydrazinium hydroxide solution o-Chlorobenzenesulfonamide Hydrazine hydrate 5-Bromo-2-methoxypyrimidine Dimethylcarbamoyl chloride HYDRAZINE Methylhydrazine 4-Amino-6-chlorobenzene-1,3-disulfonamide

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View Lastest Price from Chloramine-T manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Chloramine-T 127-65-1
Price: US $40.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/Week
Release date: 2024-05-08

Hebei Weibang Biotechnology Co., Ltd

Product: Chloramine-T 127-65-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-31

Hebei Weibang Biotechnology Co., Ltd

Product: Chloramine-T 127-65-1
Price: US $1.00/PCS
Min. Order: 1PCS
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-28

127-65-1, Chloramine-TRelated Search:

Sodium chlorite Sodium bicarbonate Sodium citrate Sodium chloride Sodium acetate 4-Chlorobenzenesulfonyl chloride Sodium sulfate p-Toluenesulfonamide Sodium p-toluenesulfonate Tosyl chloride 4-Methylbenzenesulfonhydrazide 4-Nitrobenzenesulfonyl chloride N-Acetylsulfanilyl chloride Sodium hydroxide 4-Methoxybenzenesulfonyl chloride Sodium benzoate 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Difluorochloromethane

chlorazan

chlorazene

chlorosol

chlorozone

chlorseptol

clorina

clorosan

desinfect

gyneclorina

halamid

heliogen

kloramin

kloramine-t

mannolite

monochloraminet

multichlor

N-Chloro-4-methylben-zenesulfonamide

n-chloro-4-methylbenzenesulfonamidesodiumsalt

n-chloro-4-methyl-benzenesulfonamidsodiumsalt

n-chloro-4-methylbenzylsulfonamidesodiumsalt

N-Chloro-4-tolunesulfonamide,sodiumsalt

n-chloro-p-toluenesulfonamidesodium

n-chloro-p-toluenesulfonamidsodiumsalt

n-chlorotoluenesulfonamidesodiumsalt

sodiumchloraminet

sodiumn-chloro-p-toluenesulfonamide

sodiump-toluenesulfonylchloramide

sodiumtosylchloramide

tampules

tochlorine

tolamine

tosylchloramide

Tosylchloramide sodium

TN-Chloro-4-toluenesulfonaMide sodiuM salt(HALAMID)

BenzenesulfonaMide,N-chloro-4-Methyl-, sodiuM salt (1:1)

P-TOLUENESULFONCHLORAMIDE SODIUM SALT

SODIUM-P-TOLUENESULFONCHLORAMIDE

N-CHLORO-4-METHYL-BENZENESULFONAMIDE SODIUM

N-CHLORO-4-TOLUENESULFONAMIDE, SODIUM SALT

N-CHLORO-P-TOLUENESULPHONAMIDE, SODIUM SALT

N-CHLORO-P-TOLUENESULFONAMIDE SODIUM SALT

MONOCHLORAMINE REAGENT

MIANINE

Chloramine T (Tosyl Chloramide Sodium Salt)

(n-chloro-p-toluenesulfonamido)sodium

acti-chlore

aktivin

anexol

Benzenesulfonamide,N-chloro-4-methyl-,sodiumsalt

N-Chloro-4-methylbenzenesulfonamide,sodiumsalthydrate

IODO-BEADS(R)

GYNECHLORINA

EUCLORINA

GANSIL

CHLORAZONE

CHLORAMINE T

CHLORAMINE T POLYMER BOUND

CHLORAMINE T SODIUM