Chondroitin 4-sulfate
- Product Name
- Chondroitin 4-sulfate
- CAS No.
- 24967-93-9
- Chemical Name
- Chondroitin 4-sulfate
- Synonyms
- turkadon;Chodroitin Sulfate;chondroitinasulfate;ChondroitinSulphateA;Chondroitine sulfate;CHONDROITIN SULFATE A;CHONDROITIN-4-SULFATE;chondroitinsulfatetypea;CSAChondroitin-4-sulfate;chondroitinsulfuricacida
- CBNumber
- CB7352434
- Molecular Formula
- (C14H19NO14SNa2)n
- Formula Weight
- 499.38
- MOL File
- Mol file
Chondroitin 4-sulfate Property
- alpha
- D -28 to -32°
- storage temp.
- 2-8°C
- solubility
- H2O: 0.1 g/mL, slightly hazy, faintly yellow
Safety
- WGK Germany
- 3
- F
- 3-10
- Toxicity
- mouse,LD,oral,> 15gm/kg (15000mg/kg),Zhonghua Yixue Zazhi. Chinese Medical Journal. Vol. 58, Pg. 739, 1978.
N-Bromosuccinimide Price
- Product number
- orb105119
- Product name
- Chondroitin 4-sulfate
- Purity
- >98%,Standard References Grade
- Packaging
- 20mg
- Price
- $569.5
- Updated
- 2021/12/16
- Product number
- DCL-038
- Product name
- Chondroitin4-sulfate
- Purity
- >98%,StandardReferencesGrade
- Packaging
- 20mg
- Price
- $280
- Updated
- 2021/12/16
Chondroitin 4-sulfate Chemical Properties,Usage,Production
Description
Chondroitin 4-sulfate is a natural polymer of a disaccharide consisting of glucuronic acid and N-acetyl glucosamine which is sulfated either in the 4 or 6 position. It is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA).
Chemical Properties
White or yellowish amorphous powder. Tasteless, odorless, hygroscopic, soluble in water, insoluble in organic solvents such as ethanol, acetone, ether, etc. Optical rotation -25°-+35°(c=1, H2O). There are characteristic absorption peaks at 725cm-1, 852cm-1 and 930cm-1 by infrared spectroscopy.
Uses
sodium chondroitin sulfate is described as a skin-conditioning agent, with possible anti-inflammatory properties. It can be found in such products as moisturizers and night skin care preparations. It is a derivative of natural mucopolysaccharides. Chondroitin 4-sulfate is an important structural component of cartilage and has been used as a dietary supplement to treat symptoms of joint discomfort.
Preparation
Chondroitin 4-sulfate can be extracted using the following method:
Weigh pig throat and nasal cartilage and put it into a solution of 20g/L (2%) sodium hydroxide, using a ratio of 5 times the weight of the cartilage.
Soak the cartilage in the sodium hydroxide solution and stir it intermittently.
Filter the solution when the leachate reaches 5.5°Be.
Extract the residue left on the filter by adding it to the sodium hydroxide solution again and combining the filtrate.
To remove impurities such as protein, hydrolyze the solution with crude trypsin at 50°C.
Filter the solution until it becomes clear.
Adjust the pH of the solution to 6.
Add ethanol to the solution until the alcohol content reaches 75%.
Let the solution stand overnight to allow precipitation.
Centrifuge the solution to separate the precipitate.
Wash the precipitate with absolute ethanol.
Dry the precipitate at 60°C to obtain crude chondroitin sulfate.
Definition
ChEBI: Chondroitin 4'-sulfate is a chondroitin sulfate in which the site of sulfation is carbon 4 of the N-acetylgalactosamine (GalNAc) sugar. It has a role as a mouse metabolite. It is a conjugate acid of a chondroitin 4'-sulfate anion.
References
1. Inhibition of Spiral Growth and Dissolution at the Brushite (010) Interface by Chondroitin 4-Sulfate. DOI:10.1021/acs.jpcb.8b11531
2. Evaluation of Chitosan-Based Films Containing Gelatin, Chondroitin 4-Sulfate and ZnO for Wound Healing. DOI:10.1007/s12010-017-2462-z
3. Expression and function of chondroitin 4‐sulfate and chondroitin 6‐sulfate in human glioma. DOI:10.1096/fj.201901621RRR
4. https://pubchem.ncbi.nlm.nih.gov/compound/70678540
Chondroitin 4-sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
Chondroitin 4-sulfate Suppliers
- Tel
- 13584088977
- Fax
- 025-52168336
- 2714748392@qq.com
- Country
- China
- ProdList
- 604
- Advantage
- 58
- Tel
- 13381511189 13381511189
- 2490902436@qq.com
- Country
- China
- ProdList
- 411
- Advantage
- 58
- Tel
- 15127018080
- 3119446261@qq.com
- Country
- China
- ProdList
- 478
- Advantage
- 58
- Tel
- Country
- China
- ProdList
- 42982
- Advantage
- 64
- Tel
- 021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7934
- Advantage
- 58
- Tel
- 27-81302488 18007166089
- Fax
- 027-81302088
- info@dkybpc.com
- Country
- China
- ProdList
- 2024
- Advantage
- 58
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9352
- Advantage
- 58
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15185
- Advantage
- 58
- Tel
- Fax
- -
- xg01_gj@163.com
- Country
- China
- ProdList
- 9503
- Advantage
- 50
- Tel
- 02781293128
- orders@biochemsafebuy.com
- Country
- China
- ProdList
- 9934
- Advantage
- 55
- Tel
- 021-36031160 13311776681
- 3338195766@QQ.com
- Country
- China
- ProdList
- 5175
- Advantage
- 55
- Tel
- 021-69955236-807 13918189704
- Fax
- 021-65211385
- chinaruji@chinaruji.com
- Country
- China
- ProdList
- 5176
- Advantage
- 55
- Tel
- +86-21-5877 1921
- Fax
- +86-21-5877 1925
- info@chemofchina.com
- Country
- China
- ProdList
- 9661
- Advantage
- 55
- Tel
- 18064670521
- Fax
- 0757-88210752
- 2355935187@ycphar.com
- Country
- China
- ProdList
- 4887
- Advantage
- 58
- Tel
- 0519-89885611 89885616 15312500313
- Fax
- +86(519)89885615
- luke.li@uvcs.cn.com
- Country
- China
- ProdList
- 475
- Advantage
- 58
- Tel
- 029-86629612 18202932191
- sales@pioneerbiotech.com
- Country
- China
- ProdList
- 337
- Advantage
- 55
- Tel
- 027-51831887 15337167856
- Fax
- 027-51837635 QQ1165326703
- hubeixinyuanshun@163.com
- Country
- China
- ProdList
- 10305
- Advantage
- 58
- Tel
- 0531-0531-82066716 15662658391
- Fax
- 0531-82066716
- 528732991@qq.com
- Country
- China
- ProdList
- 1022
- Advantage
- 58
- Tel
- 13849026065
- Fax
- 0371-55886196
- 2022168780qq@com
- Country
- China
- ProdList
- 59
- Advantage
- 58
- Tel
- 13437271305
- 2664022633@qq.com
- Country
- CHINA
- ProdList
- 269
- Advantage
- 58
- Tel
- 027-83232706 15871702139
- 3454407469@qq.com
- Country
- China
- ProdList
- 662
- Advantage
- 58
- Tel
- 15805159960
- 1211550495@qq.com
- Country
- China
- ProdList
- 1793
- Advantage
- 58
- Tel
- 0532-0532-66720179 15092119928
- cuiningning@bionutrichem.com
- Country
- China
- ProdList
- 109
- Advantage
- 58
- Tel
- 028-84552636 18084815636
- chensfsc@126.com
- Country
- China
- ProdList
- 1448
- Advantage
- 58
- Tel
- 025-+86-02585846866 +86-18094231287
- Fax
- 025-83144123
- eric@dasfbio.com
- Country
- China
- ProdList
- 1987
- Advantage
- 58
- Tel
- +8615255079626
- eric@witopchemical.com
- Country
- China
- ProdList
- 23556
- Advantage
- 58
- Tel
- +8618339805032
- alfa4@alfachem.cn
- Country
- China
- ProdList
- 12755
- Advantage
- 58
- Tel
- +8613367258412
- Fax
- 18062427325
- ada@ipurechemical.com
- Country
- China
- ProdList
- 10326
- Advantage
- 58
- Tel
- +86-29-89586680 +86-15129568250
- 1026@dideu.com
- Country
- China
- ProdList
- 28812
- Advantage
- 58
- Tel
- 571-88938639 +8617705817739
- Fax
- +86-571-88938652，+86-571- 88492614
- info@dycnchem.com
- Country
- CHINA
- ProdList
- 52867
- Advantage
- 58
- Tel
- 0917-3909592 13892490616
- Fax
- 09173909592
- gksales1@gk-bio.com
- Country
- China
- ProdList
- 9335
- Advantage
- 58
- Tel
- +86-029-89586680 +86-18192503167
- Fax
- +86-29-88380327
- 1026@dideu.com
- Country
- China
- ProdList
- 9177
- Advantage
- 58
- Tel
- +86-27-8439 4403 18971486879
- Fax
- +86-27-8439 4403
- sales@chemnorm.com
- Country
- CHINA
- ProdList
- 2935
- Advantage
- 58
- Tel
- +86-13806087780
- sale@simagchem.com
- Country
- China
- ProdList
- 17367
- Advantage
- 58
- Tel
- 0711-3812399 18062309155
- 156941107@qq.com
- Country
- China
- ProdList
- 2988
- Advantage
- 58
- Tel
- +86-592-6051114 +8618959220845
- sales@amoychem.com
- Country
- China
- ProdList
- 6387
- Advantage
- 58
- Tel
- 13012111162
- 2792365312@qq.com
- Country
- China
- ProdList
- 798
- Advantage
- 58
- Tel
- 027-87887055 18971192297
- Fax
- 027-87887055
- 2644074018@qq.com
- Country
- China
- ProdList
- 939
- Advantage
- 58
- Tel
- +86-023-61398051 +8613650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39916
- Advantage
- 58
- Tel
- 15332367321
- 2709392183@qq.com
- Country
- China
- ProdList
- 1068
- Advantage
- 58
- Tel
- 18613662662 15650537670
- 2708672464@qq.com
- Country
- China
- ProdList
- 1140
- Advantage
- 58
- Tel
- 021-38015121 15000105423
- chenjw@absin.cn
- Country
- China
- ProdList
- 24734
- Advantage
- 58
- Tel
- 15307151931
- Fax
- QQ-2355680
- 2355680@qq.com
- Country
- China
- ProdList
- 8229
- Advantage
- 58
- Tel
- 021-57450129 02157450129
- Fax
- 021-57450128
- 2789251452@qq.com
- Country
- China
- ProdList
- 7709
- Advantage
- 58
- Tel
- 29-86107037-8016 15891718909
- Fax
- 15891718909
- info@konochemical.com
- Country
- China
- ProdList
- 204
- Advantage
- 58
- Tel
- 029-029-81629930 18165286873
- rb@xarbkj.com
- Country
- China
- ProdList
- 329
- Advantage
- 58
- Tel
- 18971486879
- 279414929@qq.com
- Country
- CHINA
- ProdList
- 2925
- Advantage
- 58
- Tel
- 027-59506022 13419526507
- Fax
- 027-59506022
- 13419526507@163.com
- Country
- China
- ProdList
- 2936
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing1@energy-chemical.com
- Country
- China
- ProdList
- 44894
- Advantage
- 58
- Tel
- +8613063595538
- donboo@donboo.com
- Country
- China
- ProdList
- 9365
- Advantage
- 58
View Lastest Price from Chondroitin 4-sulfate manufacturers
- Product
- Chondroitin 4-sulfate 24967-93-9
- Price
- US $23.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 100000box
- Release date
- 2024-04-26
- Product
- Chondroitin sulfate 24967-93-9
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1t
- Release date
- 2023-07-11
- Product
- sodium chondroitin sulfate 24967-93-9
- Price
- US $33.00/Box
- Min. Order
- 1Box
- Purity
- 99.99%
- Supply Ability
- 10000000000
- Release date
- 2024-01-04