ChemicalBook > CAS DataBase List > Cycloleucine
Cycloleucine
- Product Name
- Cycloleucine
- CAS No.
- 52-52-8
- Chemical Name
- Cycloleucine
- Synonyms
- x201;X 201;cb1639;CYCLEU;CB 1639;nsc1026;wr14997;NSC 1026;WR 14997;wr14,997
- CBNumber
- CB7376009
- Molecular Formula
- C6H11NO2
- Formula Weight
- 129.16
- MOL File
- 52-52-8.mol
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Cycloleucine Property
- Melting point:
- 320 °C (dec.) (lit.)
- Boiling point:
- 239.22°C (rough estimate)
- Density
- 1.1426 (rough estimate)
- refractive index
- 1.4827 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO: < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)
- pka
- 2.38±0.20(Predicted)
- form
- Crystalline Flakes or Powder
- color
- White to beige
- Water Solubility
- 5 g/100 mL
- Merck
- 14,2734
- BRN
- 636626
- CAS DataBase Reference
- 52-52-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Cyclopentanecarboxylic acid, 1-amino-(52-52-8)
- EPA Substance Registry System
- Cyclopentanecarboxylic acid, 1-amino- (52-52-8)
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Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22
- Safety Statements
- 22-24/25
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- GY2625000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29224999
- Hazardous Substances Data
- 52-52-8(Hazardous Substances Data)
- Toxicity
- LD50 oral in rat: 290mg/kg
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- A48105
- Product name
- Cycloleucine
- Purity
- 97%
- Packaging
- 10g
- Price
- $190.8
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- A48105
- Product name
- Cycloleucine
- Purity
- 97%
- Packaging
- 5g
- Price
- $203
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A1063
- Product name
- 1-Aminocyclopentanecarboxylic Acid
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $36
- Updated
- 2024/03/01
TCI Chemical
- Product number
- A1063
- Product name
- 1-Aminocyclopentanecarboxylic Acid
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $102
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- B22179
- Product name
- 1-Aminocyclopentanecarboxylic acid, 97+%
- Packaging
- 1g
- Price
- $30.65
- Updated
- 2024/03/01
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Cycloleucine Chemical Properties,Usage,Production
Chemical Properties
WHITE TO BEIGE CRYSTALLINE FLAKES OR POWDER
Uses
NMDA receptor antagonist, inhibits nucleic acid methylation; adrenergic agonist
Uses
Cycloleucine can be used as a building block to synthesize:
- Phosphonylmethylaminocyclopentane-1-carboxylic acid by reacting with paraformaldehyde and diethylphosphite via Kabachnik-Field′s reaction.
- Benzo[b]thiophene-2-carboxylic acid {1-[1-(R)-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethylcarbamoyl]cyclopentyl}-amide, (MEN14268) as potential tachykinin NK2 receptor antagonist.
Uses
Cycloleucine is a synthetic amino acid used in numerous biochemical transport studies
Definition
ChEBI: A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
General Description
Cycloleucine is a nonmetabolizable amino acid widely used as a building block in peptide synthesis.
Purification Methods
Any Cl -or other anions are removed by stirring with a strong cation exchange resin (Amberlite IR-120), filtering, and washing with distilled H2O until the filtrate is free from the anion. The resin is then stirred overnight with 6N NH4OH, filtered, the filtrate is decolourised (charcoal) and evaporated to dryness in a vacuum. The residue is recrystallised from H2O/EtOH. Also crystallise it from aqueous EtOH. The hydrochloride has m 222-224o(dec). [Neelakantan & Hartung J Org Chem 23 967 1958, Connors & Ross J Chem Soc 2119 1960. O’Donnell et al. Synthesis 127 1984, Beilstein 14 IV 974.]
Cycloleucine Preparation Products And Raw materials
Raw materials
Preparation Products
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Cycloleucine Suppliers
- Tel
- --
- Fax
- --
- info@acros.com
- Country
- Belgium
- ProdList
- 6772
- Advantage
- 81
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View Lastest Price from Cycloleucine manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- Cycloleucine 52-52-8
- Price
- US $30.00-0.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-26
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Cycloleucine 52-52-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Cycloleucine 52-52-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
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