ChemicalBook > CAS DataBase List > ATTAPULGITE

ATTAPULGITE

Product Name
ATTAPULGITE
CAS No.
12174-11-7
Chemical Name
ATTAPULGITE
Synonyms
Palygorskite;attagel50;Attapulgitee;FULLERS EARTH;x250;rvm-fg;zeogel;DILUEX;Attagel;Permagel
CBNumber
CB7382453
Molecular Formula
2Al.3Mg.6O3Si
Formula Weight
583.377
MOL File
12174-11-7.mol
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ATTAPULGITE Property

Density 
2.2 g/cm3
color 
White or gray monoclinic or orthorhombic crystals
Dielectric constant
1.8(Ambient)
Stability:
Stable.
IARC
2B (Vol. 68) 1997, 3 (Vol. 68) 1997
EPA Substance Registry System
Attapulgite (12174-11-7)
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Safety

Hazardous Substances Data
12174-11-7(Hazardous Substances Data)
Toxicity
TCLo ihl-rat: 10 mg/m3/6H/13W-I:ETA BJIMAG 44,749,87
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A790568
Product name
Attapulgite
Packaging
500mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA64950
Product name
Attapulgite
Packaging
2g
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA64950
Product name
Attapulgite
Packaging
5G
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA64950
Product name
Attapulgite
Packaging
10g
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA64950
Product name
Attapulgite
Packaging
25g
Price
$500
Updated
2021/12/16
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ATTAPULGITE Chemical Properties,Usage,Production

Chemical Properties

solid

Chemical Properties

Attapulgite occurs as a light cream colored, very fine powder. Particle size ranges depend on the grade and manufacturer.

Uses

Excipient.

Uses

Worldwide attapulgite production in 1983 was estimated at about 1.1 million tons, of which 84% came from the United States. The primary use of attapulgite is as an animal waste absorbent (cat litter). Other important uses of attapulgite in the United States are as a component of drilling muds, as oil and grease absorbents, and in fertilizer and pesticide formulations.

Definition

A hydrated aluminum-magnesium silicate, the chief ingredient of fuller’s earth.

Production Methods

Attapulgite occurs naturally as the mineral palygorskite.

Hazard

Possible carcinogen.

Pharmaceutical Applications

Attapulgite is widely used as an adsorbent in solid dosage forms. Colloidal clays (such as attapulgite) absorb considerable amounts of water to form gels and in concentrations of 2–5% w/v usually form oil-in-water emulsions. Activated attapulgite, which is attapulgite that has been carefully heated to increase its absorptive capacity, is used therapeutically as an adjunct in the management of diarrhea.

Safety Profile

Suspected carcinogen with experimental neoplastigenic and tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

Safety

Attapulgite is widely used in pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material. It is not absorbed following oral administration. In oral preparations, activated attapulgite up to 9 g is used in daily divided doses as an adjunct in the management of diarrhea.

storage

Attapulgite can adsorb water. It should be stored in an airtight container in a cool, dry, location.

Incompatibilities

Attapulgite may decrease the bioavailability of some drugs such as loperamide and riboflavin. Oxidation of hydrocortisone is increased in the presence of attapulgite.

Regulatory Status

Included in nonparenteral medicines licensed in a number of countries worldwide including the UK and USA.

ATTAPULGITE Preparation Products And Raw materials

Raw materials

Preparation Products

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ATTAPULGITE Suppliers

J & K SCIENTIFIC LTD.
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View Lastest Price from ATTAPULGITE manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
ATTAPULGITE 12174-11-7
Price
US $10.70/kg
Min. Order
10kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Hebei Weibang Biotechnology Co., Ltd
Product
ATTAPULGITE 12174-11-7
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10mt
Release date
2021-01-22
Career Henan Chemical Co
Product
ATTAPULGITE 12174-11-7
Price
US $1.00-2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,10kg,100kg
Release date
2019-08-07

12174-11-7, ATTAPULGITERelated Search:


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