ChemicalBook > CAS DataBase List > 3-Bromo-5-hydroxypyridine

3-Bromo-5-hydroxypyridine

Product Name
3-Bromo-5-hydroxypyridine
CAS No.
74115-13-2
Chemical Name
3-Bromo-5-hydroxypyridine
Synonyms
5-BROMO-3-PYRIDINOL;5-Bromopyridine-3-ol;3-Bromo-5-pyridinol;5-BROMO-PYRIDIN-3-OL;3-Pyridinol, 5-bromo-;3-Hydro-5-broMo-pyridin;3-BROMO-5-HYDROXYPYRIDINE;5-BROMO-3-HYDROXYPYRIDINE;3-Hydroxy-5-bromopyridine;3-Bromo-5-hydroxypyridine95%
CBNumber
CB7423057
Molecular Formula
C5H4BrNO
Formula Weight
174
MOL File
74115-13-2.mol
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3-Bromo-5-hydroxypyridine Property

Melting point:
166-170 °C
Boiling point:
343.7±22.0 °C(Predicted)
Density 
1.788±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
8.37±0.10(Predicted)
form 
Crystalline Powder
color 
White to tan
Water Solubility 
Slightly soluble in water. Soluble in chloroform and ethyl acetate.
InChI
InChI=1S/C5H4BrNO/c6-4-1-5(8)3-7-2-4/h1-3,8H
InChIKey
VNYBIBSZZDAEOK-UHFFFAOYSA-N
SMILES
C1=NC=C(Br)C=C1O
CAS DataBase Reference
74115-13-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22-20/21/22
Safety Statements 
26-36/37/39-37-36-22
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
691836
Product name
3-Bromo-5-hydroxypyridine
Purity
97%
Packaging
1g
Price
$71.1
Updated
2023/06/20
TCI Chemical
Product number
B3969
Product name
3-Bromo-5-hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
B3969
Product name
3-Bromo-5-hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$108
Updated
2024/03/01
Alfa Aesar
Product number
H27256
Product name
3-Bromo-5-hydroxypyridine, 95%
Packaging
1g
Price
$0
Updated
2021/12/16
Oakwood
Product number
033254
Product name
5-Bromopyridin-3-ol
Packaging
1g
Price
$10
Updated
2021/12/16
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3-Bromo-5-hydroxypyridine Chemical Properties,Usage,Production

Description

3-bromo-5-hydroxypyridine is an important industrial raw material widely used in medicine, pesticides, dyes, and other industries. Since the pyridine ring has biological activity and plays an irreplaceable role in synthesising drugs that cannot be replaced by other groups or functional groups, it is a hot area in pharmaceutical research. The hydroxyl and bromine atoms in the structure of 3-bromo-5-hydroxypyridine have diverse chemical reactivity. The alcohol hydroxyl unit in its structure can undergo nucleophilic substitution reactions with common alkyl halides under alkaline conditions to obtain corresponding ether derivatives.

Chemical Properties

Light yellow needles

Uses

5-Bromo-3-methoxypyridine was refluxed with 20 mL (57%) of hydrogen bromide for 24 hours. The reaction was quenched with saturated sodium bicarbonate solution and the base mixture was extracted with 3 × 50 mL of dichloromethane. The organic fractions were pooled, dried (magnesium sulfate), filtered, and evaporated to give a white solid (3 g, >95% purity) identified as 3-bromo-5-hydroxypyridine by thin layer chromatography.

3-Bromo-5-hydroxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Bromo-5-hydroxypyridine manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
3-Bromo-5-hydroxypyridine 74115-13-2
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2024-03-19
Shanghai UCHEM Inc.
Product
3-Bromo-5-hydroxypyridine 74115-13-2
Price
US $31.00-230.00/g
Min. Order
25g
Purity
0.99
Supply Ability
25kg
Release date
2023-12-20
Suzhou Nordica Biopharma CO.,LTD
Product
5-bromopyridin-3-ol 74115-13-2
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
0.99
Supply Ability
1 tons
Release date
2024-11-15

74115-13-2, 3-Bromo-5-hydroxypyridineRelated Search:


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  • pharmacetical
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Building Blocks
  • Halogenated
  • Chemical Amines
  • Aromatics
  • Heterocycles
  • Boronic Acid
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  • Halogenated Heterocycles
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