N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

Product Name: N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
CAS No.: 16357-59-8
Chemical Name: N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
Synonyms: EEDQ;2-ETHOXY-1-ETHOXYCARBONYL-1,2-DIHYDROQUINOLINE;ethyl 2-ethoxyquinoline-1(2H)-carboxylate;ethyl 2-ethoxy-1,2-dihydroquinoline-1-carboxylate;2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester;EEDQ extrapure;2-Ethoxy-1-ethoxycar;LABOTEST-BB LT00440890;EEDQ (1-ETHOXY-CARBONYL-2-ETHOXY-1,2;ETHYL 2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECA
CBNumber: CB7436031
Molecular Formula: C14H17NO3
Formula Weight: 247.29
MOL File: 16357-59-8.mol

More

Less

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Property

Melting point:: 62-67 °C(lit.)
Boiling point:: 125-128 °C (0.1 mmHg)
Density: 1.1173 (rough estimate)
refractive index: 1.5300 (estimate)
Flash point:: 125-128°C/0.1mm
storage temp.: 2-8°C
solubility: Chlorofrom (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka: -1.27±0.40(Predicted)
form: Crystalline Powder
color: White to beige
Water Solubility: insoluble
Sensitive: Moisture Sensitive
Merck: 14,3518
BRN: 533048
CAS DataBase Reference: 16357-59-8(CAS DataBase Reference)
EPA Substance Registry System: 1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester (16357-59-8)

More

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 38-36/37/38-20/21/22
Safety Statements: 22-24/25-36/37/39-26-36
WGK Germany: 3
RTECS: VB2010000
F: 9-21
TSCA: Yes
HS Code: 29334990
Toxicity: mouse,LD50,intraperitoneal,32mg/kg (32mg/kg),Journal of Medicinal Chemistry. Vol. 14, Pg. 49, 1971.

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 149837
Product name: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
Purity: ≥99%
Packaging: 5g
Price: $21.84
Updated: 2024/03/01

Sigma-Aldrich

Product number: 149837
Product name: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
Purity: ≥99%
Packaging: 25g
Price: $70.6
Updated: 2024/03/01

TCI Chemical

Product number: E0363
Product name: 1-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $29
Updated: 2024/03/01

Alfa Aesar

Product number: A13724
Product name: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 99%
Packaging: 10g
Price: $32.2
Updated: 2024/03/01

Alfa Aesar

Product number: A13724
Product name: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 99%
Packaging: 50g
Price: $90.65
Updated: 2024/03/01

More

Less

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Chemical Properties,Usage,Production

Chemical Properties

White to pale yellow solid

Uses

Peptide condensing agent with little or no racemization. Amidation coupling reagent.

Uses

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is an irreversible membrane-bound receptor antagonist. It is used in synthetic chemistry, discovery, process R&D. It also acts as coupling reagents.

Uses

In the synthesis of peptides.

Purification Methods

Dissolve EEDQ ~180g in CHCl3, evaporate to dryness in a vacuum. Add dry Et2O (20mL) and a white solid separates on standing. Set aside for a few hours, collect the solid, wash it thoroughly with cold Et2O and dry it in a vacuum (~140g, m 63.5-65o). A further crop of solid (~25g) is obtained from the filtrate on standing overnight. [Fieser & Fieser Reagents for Organic Synthesis 2 191 1969, Belleau et al. J Am Chem Soc 90 823 1968 and 90 1651 1968, Beilstein 21/3 V 28.]

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Preparation Products And Raw materials

Raw materials

Quinoline N,N-Dimethylformamide Potassium hydroxide Ethyl chloroformate Boron trifluoride diethyl etherate Diethyl ether Dichloromethane Magnesium sulfate

Preparation Products

More

Less

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Suppliers

Americas 1 Austria 1 Belgium 3 China 253 Europe 3 Germany 8 India 13 Japan 12 South Korea 1 Switzerland 4 The Netherlands 1 United Kingdom 16 United States 51 Global 367

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-68311833 13962195826
Fax: 0512-68417696
Email: wuhao@highfine.com
Country: China
ProdList: 499
Advantage: 75

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Beijing Donghualituo Techonlogy Development Co.,Ltd.

Tel: 010-88425576
Fax: (+86)-10-88425546
Email: sales@dhltchem.com
Country: China
ProdList: 793
Advantage: 59

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

More

Less

View Lastest Price from N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline manufacturers

Watson Biotechnology Co.,Ltd

Product: EEDQ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline 16357-59-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20MT
Release date: 2024-08-22

WUHAN FORTUNA CHEMICAL CO., LTD

Product: N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline 16357-59-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2022-11-10

Henan Aochuang Chemical Co.,Ltd.

Product: N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline 16357-59-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-26

16357-59-8, N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinolineRelated Search:

DIETHOXYMETHANE Ethanol Ethoxyquin Ethyl acetate Ethoxyamine hydrochloride Ethylparaben Ethyl acrylate Ethyl pyruvate Ethyl formate ISOXADIFEN-ETHYL N-PHENYLCARBAMIC ACID METHYL ESTER N-METHYL-N-PHENYLURETHANE ethyl dimethylcarbamate Isobutyl 1,2-dihydro-2-isobutoxy-1-quinoline-carboxylate N,N,2-Trimethylbenzenamine PHENYLURETHANE N-Methylformanilide ethyl (hydroxymethyl)-carbamate

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline≥ 99% (HPLC)

Ethyl 2-ethoxy-1,2-dihydro-1-quinolinecarboxylate for synthesis

EEDQ~N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

ethyl N-(2-ethoxy-1,2-dihydroquinoline)carboxylate

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline ,98%

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, 99+% 100GR

ETHYL 2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECA

ethyl 2-ethoxyquinoline-1(2H)-carboxylate

2-Ethoxy-1-ethoxycarbonyl-1.2-dihydroquinoline 1g [16357-59-8]

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline,N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, EEDQ, Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate

EEDQ, 97+% (2-ETHOXY-1-ETHOXYCARBONYL-1, 2-DIHYDROQUINOLINE)

2-Ethoxy-1-ethoxycar

2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester

ethyl 2-ethoxy-1,2-dihydroquinoline-1-carboxylate

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline >=99%

- ethoxy - 1-2 ethoxy carbonyl - 1, 2 - dihydro quinoline

2-ethoxy-1(2h)-quinolinecarboxylicaciethylester

1,2-Dihydro-2-ethoxy-1-(ethoxycarbonyl)quinoline, Ethyl 2-ethoxyquinoline-1(2H)-carboxylate, EEDQ

Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate 97+%

EEDQ (1-ETHOXY-CARBONYL-2-ETHOXY-1,2

EEDQ, 99+%, (2-ETHOXY-1-ETHOXYCARBONYL-1 ,2-DIHYDROQUINOLINE)

N-ETHOXYCARBONYL-2-ETHOXY-1,2-DIHYDROQUINOLINE 99% ( EEDQ)

Eedq(2-Ethoxy-1-Ethoxycarbonyl-1,2-Dihydroquinoline)

1,2-Dihydro-2-ethoxy-1-quinolinecarboxylicacidester

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, 99+%

1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester

ethoxycarbonyl-2-ethoxy-1-2-dlhdroquinoline

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (EEDQ)

EEDQ extrapure

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, EEDQ, Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate

Ethyl 2-ethoxy-1(2H)-quinolinecarboxylate

Ethyl 2-ethoxy-2H-quinoline-1-carboxylate

N-Carbethoxy-2-ethoxy-1,2-dihydroquinoline

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline ,98.3%

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline（EEDQ）

1,2-Dihydro-2-ethoxy-1-quinolinecarboxylic acid ethyl ester

LABOTEST-BB LT00440890

ETHYL 1,2-DIHYDRO-2-ETHOXY-1-QUINOLINECARBOXYLATE

ETHYL 1,2-DIHYDRO-2-ETHOXYQUINOLINE-1-CARBOXYLATE

ETHYL 2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECARBOXYLATE

EEDQ

2-ETHOXY-1(2H)-QUINOLINECARBOXYLIC ACID ETHYL ESTER

2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECARBOXYLIC ACID ETHYL ESTER

2-ETHOXY-1-ETHOXYCARBONYL-1,2-DIHYDROQUINOLINE

1-ETHOXYCARBONYL-2-ETHOXY-1,2-DIHYDROQUINOLINE

2-Ethoxy-N-(ethoxycarbonyl)-1,2-dihydroquinoline

EEDQ, 99+%, (2-ETHOXY-1-ETHOXYCARBONYL-1 ,2-DIHYDROQUINO

N-ETHOXYCARBONYL-2-ETHOXY-1,2-DIHYDROQUINOLINE

1-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline&gt

EEDQ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline,99%

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline USP/EP/BP

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline 16357-59-8

16357-59-8

C11H17ON3

Condensation & Active Esterification

Coupling Reactions (Peptide Synthesis)

Peptide Synthesis

Others