2-Amino-4-nitro anisidine Property

Melting point:

117-119 °C(lit.)

Boiling point:

337.07°C (rough estimate)

Density 

1.2068

vapor pressure 

0.04Pa

refractive index 

1.6010 (estimate)

Flash point:

119℃

solubility 

382mg/L in organic solvents at 20 ℃

pka

2.42±0.10(Predicted)

Colour Index 

37130

Water Solubility 

Slightly soluble. <0.01 g/100 mL at 19.5 ºC

BRN 

879620

Stability:

Stable, but may be moisture sensitive. Incompatible with water, acids, strong oxidizing agents, acid chlorides, acid anhydrides, chloroformates, liquid anisidine.

LogP

1.16 at 23℃

CAS DataBase Reference

99-59-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2-methoxy-5-nitro-(99-59-2)

IARC

3 (Vol. 27, Sup 7) 1987

EPA Substance Registry System

2-Methoxy-5-nitroaniline (99-59-2)

Safety

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-45-36/37

WGK Germany 

2

RTECS 

BZ7175000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

2922290090

Hazardous Substances Data

99-59-2(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H311Toxic in contact with skin

H332Harmful if inhaled

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P405Store locked up.

2-Amino-4-nitro anisidine Chemical Properties,Usage,Production

Chemical Properties

orange to brown powder

Chemical Properties

5-Nitro-o-anisidine is an orange-red crystalline compound.

Uses

2-Methoxy-5-nitroaniline was used in the synthesis of 5-(9-acridinylamino)-p-anisidines via reaction with 9-anilinoacridines. It was also used in the synthesis of disazo disperse dyes containing nitro and methoxy groups, used for the dyeing of polyester fibre.

Definition

ChEBI: 2-methoxy-5-nitroaniline is a member of 4-nitroanisoles and a substituted aniline.

General Description

Orange-red needles or orange powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Amino-4-nitro anisidine is incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides and chloroformates .

Fire Hazard

Flash point data for 2-Amino-4-nitro anisidine are not available. 2-Amino-4-nitro anisidine is probably combustible.

Flammability and Explosibility

Non flammable

Safety Profile

Suspected carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS OF AROMATIC HYDROCARBONS.

Potential Exposure

5-Nitro-o-anisidine is a chemical intermediate in the production of C.I. Pigment red 23, which is used as a colorant for commodities, such as printing inks, interior latex paints; lacquers, rubber, plastics, floor coverings; paper coating; and textiles. It is also used with other C.I. coupling components to produce various hues of red, brown, yellow, and violet on cotton, silk, acetate and nylon.

Shipping

UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides; acid anhydrides; chloroformates.

Waste Disposal

Incineration (982℃, 2.0 seconds minimum) with scrubbing for nitrogen oxides abatement.